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DK0628077T3 - Humaniserede antistoffer, som er rettet mod A33-antigen - Google Patents

Humaniserede antistoffer, som er rettet mod A33-antigen

Info

Publication number
DK0628077T3
DK0628077T3 DK94902059T DK94902059T DK0628077T3 DK 0628077 T3 DK0628077 T3 DK 0628077T3 DK 94902059 T DK94902059 T DK 94902059T DK 94902059 T DK94902059 T DK 94902059T DK 0628077 T3 DK0628077 T3 DK 0628077T3
Authority
DK
Denmark
Prior art keywords
antigen
directed against
humanized antibodies
antibodies directed
antibody
Prior art date
Application number
DK94902059T
Other languages
English (en)
Inventor
David John King
John Robert Adair
Raymond John Owens
Original Assignee
Celltech Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929225853A external-priority patent/GB9225853D0/en
Priority claimed from GB939315249A external-priority patent/GB9315249D0/en
Application filed by Celltech Therapeutics Ltd filed Critical Celltech Therapeutics Ltd
Application granted granted Critical
Publication of DK0628077T3 publication Critical patent/DK0628077T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK94902059T 1992-12-10 1993-12-10 Humaniserede antistoffer, som er rettet mod A33-antigen DK0628077T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929225853A GB9225853D0 (en) 1992-12-10 1992-12-10 Antigen-binding proteins
GB939315249A GB9315249D0 (en) 1993-07-22 1993-07-22 Antigen-binding proteins
PCT/GB1993/002529 WO1994013805A1 (en) 1992-12-10 1993-12-10 Humanised antibodies directed against a33 antigen

Publications (1)

Publication Number Publication Date
DK0628077T3 true DK0628077T3 (da) 2002-07-01

Family

ID=26302139

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94902059T DK0628077T3 (da) 1992-12-10 1993-12-10 Humaniserede antistoffer, som er rettet mod A33-antigen

Country Status (12)

Country Link
EP (1) EP0628077B1 (da)
JP (1) JPH07504334A (da)
AT (1) ATE214734T1 (da)
AU (1) AU675268B2 (da)
CA (1) CA2128544A1 (da)
DE (1) DE69331735T2 (da)
DK (1) DK0628077T3 (da)
ES (1) ES2173910T3 (da)
GB (1) GB2278357B (da)
NZ (1) NZ258618A (da)
PT (1) PT628077E (da)
WO (1) WO1994013805A1 (da)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5851526A (en) * 1985-04-19 1998-12-22 Ludwig Institute For Cancer Research Methods of treating colon cancer utilizing tumor-specific antibodies
US6190640B1 (en) * 1985-04-19 2001-02-20 Ludwig Institute For Cancer Research Method for treating neoplasia using humanized antibodies which bind to antigen A33
GB9215541D0 (en) 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
GB9215540D0 (en) * 1992-07-22 1992-09-02 Celltech Ltd Protein expression system
US6307026B1 (en) * 1992-12-10 2001-10-23 Celltech Limited Humanized antibodies directed against A33 antigen
CA2126819A1 (en) * 1993-07-09 1995-01-10 Richard P. Mccabe Kit and method for pretargeting
GB9424449D0 (en) * 1994-12-02 1995-01-18 Wellcome Found Antibodies
US5712374A (en) * 1995-06-07 1998-01-27 American Cyanamid Company Method for the preparation of substantiallly monomeric calicheamicin derivative/carrier conjugates
US5712369A (en) * 1995-08-24 1998-01-27 Ludwig Institute For Cancer Research Isolated protein which binds to A33 antibody, and peptides corresponding to portions of the protein
AU6537798A (en) * 1997-03-14 1998-10-12 Denise Casentini-Borocz Targeted cytolysis of cancer cells
AU1102401A (en) * 1999-10-22 2001-05-08 Ludwig Institute For Cancer Research Methods for reducing the effects of cancers that express a33 antigen using a33 antigen specific immunoglobulin products
DE60126602T2 (de) 2000-04-21 2007-11-22 Fuso Pharmaceutical Industries, Ltd. Neue collectine
BR0213303A (pt) * 2001-10-15 2005-06-07 Immunomedics Inc Proteìnas de ligação de alvejamento direto
US7579187B2 (en) * 2004-09-06 2009-08-25 Kyoma Hakko Kirin Co., Ltd. Anti-A33 antibody
EP2937360A1 (en) 2005-06-17 2015-10-28 Merck Sharp & Dohme Corp. Ilt3 binding molecules and uses therefor
EP2041180B8 (en) * 2006-06-19 2014-03-05 Liquidating Trust Ilt3 binding molecules and uses therefor
EP3564386B1 (en) 2016-12-27 2021-12-08 Chugai Seiyaku Kabushiki Kaisha Method for evaluating immunogenicity of test substance
CA3076611A1 (en) * 2017-09-23 2019-03-28 Memorial Sloan Kettering Cancer Center A33 antibody compositions and methods of using the same in radioimmunotherapy
CN110540591A (zh) * 2019-08-09 2019-12-06 无锡傲锐东源生物科技有限公司 一种抗糖蛋白A33（Glycoprotein A33）单克隆抗体及其免疫检测应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091542A (en) * 1990-03-09 1992-02-25 Hybritech Incorporated Tris-maleimido compounds as intermediates in trifunctional antibody synthesis
GB9012995D0 (en) * 1990-06-11 1990-08-01 Celltech Ltd Multivalent antigen-binding proteins
GB9014932D0 (en) * 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
GB9112536D0 (en) * 1991-06-11 1991-07-31 Celltech Ltd Chemical compounds

Also Published As

Publication number Publication date
EP0628077A1 (en) 1994-12-14
GB2278357B (en) 1997-03-05
EP0628077B1 (en) 2002-03-20
PT628077E (pt) 2002-07-31
ES2173910T3 (es) 2002-11-01
AU5656894A (en) 1994-07-04
DE69331735D1 (de) 2002-04-25
CA2128544A1 (en) 1994-06-23
ATE214734T1 (de) 2002-04-15
DE69331735T2 (de) 2002-09-26
JPH07504334A (ja) 1995-05-18
GB2278357A (en) 1994-11-30
WO1994013805A1 (en) 1994-06-23
AU675268B2 (en) 1997-01-30
GB9415880D0 (en) 1994-09-28
NZ258618A (en) 1997-02-24

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