DK0619837T3 - Fremgangsmåde til opnåelse af glycosyltransferaser - Google Patents
Fremgangsmåde til opnåelse af glycosyltransferaserInfo
- Publication number
- DK0619837T3 DK0619837T3 DK93901223T DK93901223T DK0619837T3 DK 0619837 T3 DK0619837 T3 DK 0619837T3 DK 93901223 T DK93901223 T DK 93901223T DK 93901223 T DK93901223 T DK 93901223T DK 0619837 T3 DK0619837 T3 DK 0619837T3
- Authority
- DK
- Denmark
- Prior art keywords
- immobilized
- glycosyltransferase
- acceptor moiety
- complex
- obtaining
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/815—Enzyme separation or purification by sorption
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/810,858 US5874261A (en) | 1988-09-02 | 1991-12-20 | Method for the purification of glycosyltransferases |
PCT/US1992/010891 WO1993013198A1 (en) | 1991-12-20 | 1992-12-21 | A method for obtaining glycosyltransferases |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0619837T3 true DK0619837T3 (da) | 2001-12-03 |
Family
ID=25204895
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93901223T DK0619837T3 (da) | 1991-12-20 | 1992-12-21 | Fremgangsmåde til opnåelse af glycosyltransferaser |
Country Status (14)
Country | Link |
---|---|
US (1) | US5874261A (da) |
EP (1) | EP0619837B1 (da) |
JP (1) | JPH07502412A (da) |
AT (1) | ATE207117T1 (da) |
AU (1) | AU685387B2 (da) |
CA (1) | CA2126213A1 (da) |
DE (1) | DE69232138T2 (da) |
DK (1) | DK0619837T3 (da) |
ES (1) | ES2162619T3 (da) |
FI (1) | FI942916A (da) |
NO (1) | NO942317D0 (da) |
PT (1) | PT619837E (da) |
RU (1) | RU94034735A (da) |
WO (1) | WO1993013198A1 (da) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0481038B1 (en) | 1990-04-16 | 2002-10-02 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
KR920702721A (ko) * | 1990-04-16 | 1992-10-06 | 원본미기재 | 사카라이드 조성물, 그의 합성 방법 및 장치 |
US6518051B1 (en) | 1991-04-11 | 2003-02-11 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
US5665561A (en) * | 1994-06-06 | 1997-09-09 | The Rockefeller University | Modulators of pneumococcal adherence to pulmonary and vascular cells and diagnostic and therapeutic applications |
US5545553A (en) * | 1994-09-26 | 1996-08-13 | The Rockefeller University | Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them |
US6096725A (en) * | 1997-07-02 | 2000-08-01 | Neose Technologies, Inc. | Methods of using αGal oligosaccharides as immune system targeting agents |
AU1585999A (en) | 1997-11-12 | 1999-05-31 | Neurotherapeutics | Methods for the detection and treatment of disease using a glycosyltransferase |
US20040204381A1 (en) * | 1997-11-12 | 2004-10-14 | Moskal Joseph R | Detection and treatment of glyco-enzyme-related disease |
US20030143662A1 (en) * | 1998-06-16 | 2003-07-31 | Cummings Richard D. | Glycosulfopeptide inhibitors of leukocyte rolling and methods of use thereof |
US7223845B2 (en) | 1998-06-16 | 2007-05-29 | The Board Of Regents Of The University Of Oklahoma | Synthetic glycosulfopeptides and methods of synthesis thereof |
WO1999065712A2 (en) | 1998-06-16 | 1999-12-23 | The Board Of Regents Of The University Of Oklahoma | Glycosulfopeptides and methods of synthesis and use thereof |
US20030235884A1 (en) * | 1999-06-15 | 2003-12-25 | Cummings Richard D. | Polynucleotides encoding core 1 beta3-galactosyl transferase and methods of use thereof |
US6492152B1 (en) | 1999-06-15 | 2002-12-10 | The Board Of Regents Of The University Of Oklahoma | Core 1 β3-galactosyl transferases and methods of use thereof |
US20030059915A1 (en) * | 1999-06-15 | 2003-03-27 | Canfield William M. | Core 1 beta3-galactosyl transferases and methods of use thereof |
AU1431101A (en) | 1999-10-04 | 2001-05-10 | University Of Maryland Biotechnology Institute | Novel adjuvant comprising a lipopolysaccharide antagonist |
US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
US7214660B2 (en) | 2001-10-10 | 2007-05-08 | Neose Technologies, Inc. | Erythropoietin: remodeling and glycoconjugation of erythropoietin |
WO2004099231A2 (en) | 2003-04-09 | 2004-11-18 | Neose Technologies, Inc. | Glycopegylation methods and proteins/peptides produced by the methods |
AU2003201619A1 (en) * | 2002-01-18 | 2003-07-30 | Biotie Therapies Corporation | Novel binding epitopes for helicobacter pylori and use thereof |
US7309600B2 (en) | 2003-02-12 | 2007-12-18 | University Of Iowa Research Foundation | Haemophilus influenzae sialyltransferase and methods of use thereof |
WO2005012484A2 (en) | 2003-07-25 | 2005-02-10 | Neose Technologies, Inc. | Antibody-toxin conjugates |
US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
US7893041B2 (en) | 2003-12-05 | 2011-02-22 | Children's Hospital Medical Center | Oligosaccharide compositions and use thereof in the treatment of infection |
HUE026826T2 (en) | 2004-10-29 | 2016-07-28 | Ratiopharm Gmbh | Modeling and glycopegylation of fibroblast growth factor (FGF) |
EP1858543B1 (en) | 2005-01-10 | 2013-11-27 | BioGeneriX AG | Glycopegylated granulocyte colony stimulating factor |
TWI264608B (en) * | 2005-04-08 | 2006-10-21 | Delta Electronics Inc | Light tunnel module |
WO2006121569A2 (en) | 2005-04-08 | 2006-11-16 | Neose Technologies, Inc. | Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants |
US20070105755A1 (en) | 2005-10-26 | 2007-05-10 | Neose Technologies, Inc. | One pot desialylation and glycopegylation of therapeutic peptides |
US20090048440A1 (en) | 2005-11-03 | 2009-02-19 | Neose Technologies, Inc. | Nucleotide Sugar Purification Using Membranes |
US20080280818A1 (en) | 2006-07-21 | 2008-11-13 | Neose Technologies, Inc. | Glycosylation of peptides via o-linked glycosylation sequences |
JP2010505874A (ja) | 2006-10-03 | 2010-02-25 | ノヴォ ノルディスク アー/エス | ポリペプチドコンジュゲートの精製方法 |
ES2406267T3 (es) | 2007-04-03 | 2013-06-06 | Biogenerix Ag | Métodos de tratamiento usando G-CSF glicopegilado |
MX2009013259A (es) | 2007-06-12 | 2010-01-25 | Novo Nordisk As | Proceso mejorado para la produccion de azucares de nucleotidos. |
CN103497246B (zh) | 2008-02-27 | 2016-08-10 | 诺沃—诺迪斯克有限公司 | 缀合的因子viii分子 |
WO2010120682A1 (en) | 2009-04-13 | 2010-10-21 | Morrow Ardythe L | Milk oligosaccharide compositions and use thereof in treating infection in animals |
UA110325C2 (en) | 2009-07-03 | 2015-12-25 | Australian Biomedical Company Pty Ltd | Medicinal carbohydrates for treating respiratory conditions |
ES2651067T3 (es) | 2009-07-06 | 2018-01-24 | Children's Hospital Medical Center | Inhibición de la inflamación con oligosacáridos de la leche |
ES2671555T3 (es) | 2011-06-07 | 2018-06-07 | Hero Ag | Obtención de oligosacáridos mediante un proceso biotecnológico |
RU2624241C1 (ru) * | 2016-03-25 | 2017-07-03 | Акционерное Общество "ГенТерра" | Твердофазный носитель для иммобилизации и/или хранения биологических образцов, содержащих нуклеиновые кислоты |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4184917A (en) * | 1974-04-01 | 1980-01-22 | Sandoz Ltd. | Process for producing a structurally modified interferon |
US4219571A (en) * | 1978-06-15 | 1980-08-26 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Process for producing a sweetener |
US4261976A (en) * | 1978-10-03 | 1981-04-14 | The Massachusetts General Hospital | Method and glycoprotein composition for inhibition of growth of transformed cells and tumors |
JPS5836959B2 (ja) * | 1980-08-21 | 1983-08-12 | 三井製糖株式会社 | 固定化α−グルコシルトランスフエラ−ゼによるパラチノ−スの製造法 |
JPS58870A (ja) * | 1981-06-20 | 1983-01-06 | Hayashibara Biochem Lab Inc | 飲食物及びその製造方法 |
FR2509313A1 (fr) * | 1981-07-08 | 1983-01-14 | Choay Sa | Derives de 3-fucosyl-n-acetyl lactosamine, leur preparation et leurs applications biologiques |
JPS58149697A (ja) * | 1982-02-27 | 1983-09-06 | Dainippon Ink & Chem Inc | β−1,3グリコシルステビオシドの製造方法 |
US4569909A (en) * | 1982-06-03 | 1986-02-11 | Seitetsu Kagaku Co., Ltd. | Process for preparing uridine diphosphate-N-acetylgalactosamine |
US4770994A (en) * | 1982-07-30 | 1988-09-13 | Abbott Laboratories | Determination of carbohydrate acceptors |
US4557927A (en) * | 1983-03-10 | 1985-12-10 | Kabushiki Kaisha Hoyashibara | Food products and process for producing same |
GB8316790D0 (en) * | 1983-06-21 | 1983-07-27 | Tate & Lyle Plc | Chemical process |
DE3446380C1 (de) * | 1984-12-19 | 1986-05-22 | Pfeifer & Langen, 5000 Köln | Suessungsmittel,Verfahren zur Herstellung und Verwendung desselben |
SE451849B (sv) * | 1985-12-11 | 1987-11-02 | Svenska Sockerfabriks Ab | Sett att syntetisera glykosidiska bindningar samt anvendning av pa detta sett erhallna produkter |
NL8701616A (nl) * | 1987-07-09 | 1989-02-01 | Stamicarbon | Fructosyltransferase en bereiding van fructose-oligomeren daarmee. |
SE466403B (sv) * | 1988-03-24 | 1992-02-10 | Kurt G I Nilsson | Saett att syntetisera oligosackarider |
EP0356048A3 (en) * | 1988-08-05 | 1990-11-14 | Uop | Novel cylodextrin glycosyltransferases |
DK626488D0 (da) * | 1988-11-10 | 1988-11-10 | Torben Falck Oerntoft | Fremgangsmaade til udtagning af en sekretproeve via en legemsaabning og til praeparation af proeven med henblik paa kvantitativ bestemmelse af molekylaere strukturer og enzymaktivitet i proeven samt proeveudtagningsindretning til brug derved |
EP0481038B1 (en) * | 1990-04-16 | 2002-10-02 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
-
1991
- 1991-12-20 US US07/810,858 patent/US5874261A/en not_active Expired - Fee Related
-
1992
- 1992-12-21 JP JP5511742A patent/JPH07502412A/ja active Pending
- 1992-12-21 RU RU94034735/13A patent/RU94034735A/ru unknown
- 1992-12-21 AT AT93901223T patent/ATE207117T1/de not_active IP Right Cessation
- 1992-12-21 EP EP93901223A patent/EP0619837B1/en not_active Expired - Lifetime
- 1992-12-21 AU AU33236/93A patent/AU685387B2/en not_active Ceased
- 1992-12-21 DE DE69232138T patent/DE69232138T2/de not_active Expired - Fee Related
- 1992-12-21 ES ES93901223T patent/ES2162619T3/es not_active Expired - Lifetime
- 1992-12-21 CA CA002126213A patent/CA2126213A1/en not_active Abandoned
- 1992-12-21 WO PCT/US1992/010891 patent/WO1993013198A1/en active IP Right Grant
- 1992-12-21 PT PT93901223T patent/PT619837E/pt unknown
- 1992-12-21 DK DK93901223T patent/DK0619837T3/da active
-
1994
- 1994-06-17 NO NO942317A patent/NO942317D0/no unknown
- 1994-06-17 FI FI942916A patent/FI942916A/fi unknown
Also Published As
Publication number | Publication date |
---|---|
AU3323693A (en) | 1993-07-28 |
CA2126213A1 (en) | 1993-06-24 |
PT619837E (pt) | 2002-03-28 |
FI942916A0 (fi) | 1994-06-17 |
ES2162619T3 (es) | 2002-01-01 |
ATE207117T1 (de) | 2001-11-15 |
EP0619837A1 (en) | 1994-10-19 |
EP0619837A4 (en) | 1995-11-15 |
RU94034735A (ru) | 1996-07-20 |
US5874261A (en) | 1999-02-23 |
NO942317L (da) | 1994-08-09 |
DE69232138D1 (de) | 2001-11-22 |
NO942317D0 (no) | 1994-06-17 |
AU685387B2 (en) | 1998-01-22 |
JPH07502412A (ja) | 1995-03-16 |
EP0619837B1 (en) | 2001-10-17 |
DE69232138T2 (de) | 2002-06-06 |
FI942916A (fi) | 1994-06-17 |
WO1993013198A1 (en) | 1993-07-08 |
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