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DK0420042T3 - Solid pharmaceutical forms with high verapamil content - Google Patents

Solid pharmaceutical forms with high verapamil content

Info

Publication number
DK0420042T3
DK0420042T3 DK90118101.6T DK90118101T DK0420042T3 DK 0420042 T3 DK0420042 T3 DK 0420042T3 DK 90118101 T DK90118101 T DK 90118101T DK 0420042 T3 DK0420042 T3 DK 0420042T3
Authority
DK
Denmark
Prior art keywords
solid pharmaceutical
pharmaceutical forms
verapamil
content
verapamil content
Prior art date
Application number
DK90118101.6T
Other languages
Danish (da)
Inventor
Thomas Dr Moest
Helmut Dr Fricke
Ernst Dr Flaig
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Application granted granted Critical
Publication of DK0420042T3 publication Critical patent/DK0420042T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

A solid pharmaceutical form with a verapamil content of at least 90 % by weight is produced by granulation at 30 to 50 DEG C with a little water, drying and, where appropriate, conventional tabletting or by pelleting, where the granules obtained as described are, after cooling, moistened once again and compacted and dried in a granulating mixer at 30 to 55 DEG C.
DK90118101.6T 1989-09-28 1990-09-20 Solid pharmaceutical forms with high verapamil content DK0420042T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3932378A DE3932378A1 (en) 1989-09-28 1989-09-28 SOLID MEDICAL FORM WITH A HIGH VERAPAMIL CONTENT

Publications (1)

Publication Number Publication Date
DK0420042T3 true DK0420042T3 (en) 1992-10-05

Family

ID=6390380

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90118101.6T DK0420042T3 (en) 1989-09-28 1990-09-20 Solid pharmaceutical forms with high verapamil content

Country Status (8)

Country Link
EP (1) EP0420042B1 (en)
JP (1) JP3100615B2 (en)
AT (1) ATE78159T1 (en)
CA (1) CA2026384C (en)
DE (2) DE3932378A1 (en)
DK (1) DK0420042T3 (en)
ES (1) ES2043210T3 (en)
GR (1) GR3005754T3 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993013756A1 (en) * 1992-01-10 1993-07-22 Obschestvo S Ogranichennoy Otvetstvennostyu Meditsinsky Nauchno-Proizvodstvennoy Komplex 'biotiki' Granulated pharmaceutical composition and method of obtaining it

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3113901A1 (en) * 1981-04-07 1982-10-28 Basf Ag, 6700 Ludwigshafen ACTIVE SUBSTANCE PREPARATION FOR ORAL APPLICATION
LU86099A1 (en) * 1985-09-30 1987-04-02 Pharlyse EXTENDED RELEASE GALENIC FORMS OF VERAPAMIL, THEIR MANUFACTURE AND THE MEDICINAL PRODUCTS CONTAINING THEM
IT1227336B (en) * 1987-09-11 1991-04-08 Squibb & Sons Inc PHARMACEUTICAL COMPOSITION CONTAINING A HIGH MEDICATION LOAD AND PROCEDURE FOR ITS PREPARATION

Also Published As

Publication number Publication date
JP3100615B2 (en) 2000-10-16
EP0420042A3 (en) 1991-04-24
ATE78159T1 (en) 1992-08-15
EP0420042B1 (en) 1992-07-15
DE3932378A1 (en) 1991-04-11
JPH03167122A (en) 1991-07-19
ES2043210T3 (en) 1993-12-16
EP0420042A2 (en) 1991-04-03
GR3005754T3 (en) 1993-06-07
CA2026384C (en) 2002-04-09
CA2026384A1 (en) 1991-03-29
DE59000209D1 (en) 1992-08-20

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