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DK0410236T3 - Fremgangsmåde til fremstilling af caratenoidpræparater - Google Patents

Fremgangsmåde til fremstilling af caratenoidpræparater

Info

Publication number
DK0410236T3
DK0410236T3 DK90113500.4T DK90113500T DK0410236T3 DK 0410236 T3 DK0410236 T3 DK 0410236T3 DK 90113500 T DK90113500 T DK 90113500T DK 0410236 T3 DK0410236 T3 DK 0410236T3
Authority
DK
Denmark
Prior art keywords
caratenoid
preparations
preparation
carotenoid
emulsified
Prior art date
Application number
DK90113500.4T
Other languages
English (en)
Inventor
Ernst Cathrein
Hermann Stein
Hansj Stoller
Klaus Viardot
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4241388&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0410236(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of DK0410236T3 publication Critical patent/DK0410236T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/24Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/40Colouring or decolouring of foods
    • A23L5/42Addition of dyes or pigments, e.g. in combination with optical brighteners
    • A23L5/43Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
    • A23L5/44Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives using carotenoids or xanthophylls
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/01Hydrocarbons
    • A61K31/015Hydrocarbons carbocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • A61K9/1623Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09BORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00Dyes of natural origin prepared from natural sources, e.g. vegetable sources

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Nutrition Science (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK90113500.4T 1989-07-25 1990-07-14 Fremgangsmåde til fremstilling af caratenoidpræparater DK0410236T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH277889 1989-07-25

Publications (1)

Publication Number Publication Date
DK0410236T3 true DK0410236T3 (da) 1993-12-13

Family

ID=4241388

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90113500.4T DK0410236T3 (da) 1989-07-25 1990-07-14 Fremgangsmåde til fremstilling af caratenoidpræparater

Country Status (6)

Country Link
US (1) US5364563A (da)
EP (1) EP0410236B1 (da)
JP (1) JP2572877B2 (da)
AT (1) ATE96312T1 (da)
DE (1) DE59003205D1 (da)
DK (1) DK0410236T3 (da)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
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DE4329446A1 (de) * 1993-09-01 1995-03-02 Basf Ag Verfahren zur Herstellung von feinteiligen Farb- oder Wirkstoffzubereitungen
DE4424085A1 (de) * 1994-07-11 1996-01-18 Basf Ag Kaltwasserdispergierbare Zubereitungen fettlöslicher Wirkstoffe
EP0718284B1 (en) * 1994-12-21 1999-08-18 F. Hoffmann-La Roche Ag Carotenoid ketones and esters
JP3555640B2 (ja) * 1996-05-10 2004-08-18 ライオン株式会社 天然カロチノイドを包含した多芯型構造のマイクロカプセル並びに錠剤、食品用及び医薬品用配合剤
ATE262316T1 (de) * 1996-05-14 2004-04-15 Dsm Ip Assets Bv Herstellungsverfahren für carotenoid- zusammensetzungen
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DE19653410A1 (de) 1996-12-20 1998-06-25 Basf Ag Verwendung von Carotinoid-Solubilisaten zum Färben von Lebensmitteln und pharmazeutischen Zubereitungen
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DE19831865A1 (de) 1998-07-16 2000-01-20 Basf Ag Verwendung von Schwefel-organischen Verbindungen als Mittel zur bathochromen Verschiebung der UV/Vis-Absorptionsbande von Carotinoiden
DE19838636A1 (de) 1998-08-26 2000-03-02 Basf Ag Carotinoid-Formulierungen, enthaltend ein Gemisch aus beta-Carotin, Lycopin und Lutein
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US6582721B1 (en) 1999-09-17 2003-06-24 Alcon, Inc. Stable carotene-xanthophyll beadlet compositions and methods of use
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DE10042833A1 (de) * 2000-08-30 2002-03-14 Basf Ag Feste Zubereitungen mit einer Multi-Kern Struktur
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DE10104494A1 (de) 2001-01-31 2002-08-01 Basf Ag Verfahren zur Herstellung von Trockenpulvern eines oder mehrerer Carotinoide
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ES2195758B1 (es) 2001-12-31 2005-03-01 Antibioticos, S.A.U. Procedimiento mejorado de produccion de licopeno mediante la fermentacion de cepas seleccionadas de blakeslea trispora, formulaciones y usos del licopeno obtenido.
US6663900B2 (en) * 2002-02-01 2003-12-16 Kemin Foods, Lc Microcapsules having high carotenoid content
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US20050009788A1 (en) * 2002-07-29 2005-01-13 Lockwood Samuel Fournier Carotenoid ester analogs or derivatives for controlling connexin 43 expression
US20050004235A1 (en) * 2002-07-29 2005-01-06 Lockwood Samuel Fournier Carotenoid analogs or derivatives for the inhibition and amelioration of liver disease
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JPWO2004087645A1 (ja) * 2003-03-28 2006-06-29 株式会社クラレ カロテノイド乳化液の製造方法
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JP5142988B2 (ja) * 2005-05-23 2013-02-13 ファレス ファーマシューティカル リサーチ エヌ.ブイ. 直接溶解
EP1901733B1 (en) * 2005-05-23 2016-04-06 President and Fellows of Harvard College Huperzine for use in the treatment of neuropathic pain
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MX2009008019A (es) * 2007-02-23 2009-08-07 Basf Se Uso de nanoparticulas carotenoides dispersibles en agua como moduladores de sabor, moduladores de sabor que contiene nanoparticulas carotenoides dispersibles en agua y metodo para modulacion de sabor.
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CL2008003484A1 (es) * 2007-11-23 2010-01-11 Basf Se Procedimiento para la preparacion de soluciones de carotenoides en un aceite apropiado para comestibles que comprende proporcionara una suspension de carotenoides en aceite; ii. calentar continuamente; iii. enfriar la solucion con una solucion mas fria del carotenoides en un aceite apropiado para comestible.
WO2009068432A1 (de) 2007-11-29 2009-06-04 Basf Se Pulverförmige carotinoidzubereitung für die färbung von getränken
EP2343986B2 (de) 2008-10-07 2021-04-21 Basf Se Gebrauchfertige, stabile emulsion
ES2621184T3 (es) 2009-03-30 2017-07-03 Basf Se Suspensión estable, lista para su uso, de partículas de beta-caroteno parcialmente amorfas
EP2601221A1 (de) 2010-08-05 2013-06-12 Basf Se Stabilisator
US20120157547A1 (en) 2010-12-21 2012-06-21 Ricardo Montoya-Olvera Compositions and applications of carotenoids of improved absorption and bioavailability
KR20140077967A (ko) 2011-11-18 2014-06-24 후지필름 가부시키가이샤 카로티노이드 함유 조성물 및 그 제조 방법
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CN104274428B (zh) * 2013-07-09 2016-04-13 浙江新维普添加剂有限公司 油分散性类胡萝卜素制剂的制备方法
CN103756360B (zh) * 2014-01-15 2016-03-02 山东星光生物科技有限公司 玉米黄色素微粉的制备方法
JP6954917B2 (ja) * 2016-03-24 2021-10-27 ビーエイエスエフ・ソシエタス・エウロパエアBasf Se 多相活性物質調製物
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CN111838648B (zh) * 2020-06-16 2023-04-25 嘉必优生物技术(武汉)股份有限公司 一种生产纳米级类胡萝卜素乳液的装置及方法
CN114276285B (zh) * 2021-12-28 2024-06-04 大连医诺生物股份有限公司 一种类胡萝卜素制剂、其制备方法及应用
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CN118525919A (zh) 2023-02-22 2024-08-23 浙江可明生物医药有限公司 类胡萝卜素制剂的制备方法

Family Cites Families (8)

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US2861891A (en) * 1956-12-13 1958-11-25 Hoffmann La Roche Water dispersible carotenoid compositions and process of making the same
DE1211911B (de) * 1959-09-08 1966-03-03 Hoffmann La Roche Verfahren zur Herstellung eines insbesondere zum Faerben von Lebens- und Futtermitteln geeigneten Carotinoidpraeparates
US3110598A (en) * 1959-09-08 1963-11-12 Hoffmann La Roche Process of making a carotenoid preparation
DE2943267A1 (de) * 1979-10-26 1981-05-07 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinstverteilten carotinoiden
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DE3610191A1 (de) * 1986-03-26 1987-10-01 Basf Ag Verfahren zur herstellung von feinteiligen, wasserdispergierbaren carotinoid-praeparationen
DE3611229A1 (de) * 1986-04-04 1987-10-08 Basf Ag Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinoidpraeparaten
DE3702030A1 (de) * 1987-01-24 1988-08-04 Basf Ag Pulverfoermige, wasserdispergierbare carotinoid-zubereitungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
JPH0366615A (ja) 1991-03-22
EP0410236A3 (en) 1991-07-03
EP0410236B1 (de) 1993-10-27
US5364563A (en) 1994-11-15
DE59003205D1 (de) 1993-12-02
ATE96312T1 (de) 1993-11-15
EP0410236A2 (de) 1991-01-30
JP2572877B2 (ja) 1997-01-16

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