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DK0483320T3 - Prolonged-release pharmaceutical compositions for oral administration and methods for their preparation - Google Patents

Prolonged-release pharmaceutical compositions for oral administration and methods for their preparation

Info

Publication number
DK0483320T3
DK0483320T3 DK91909171.0T DK91909171T DK0483320T3 DK 0483320 T3 DK0483320 T3 DK 0483320T3 DK 91909171 T DK91909171 T DK 91909171T DK 0483320 T3 DK0483320 T3 DK 0483320T3
Authority
DK
Denmark
Prior art keywords
prolonged
preparation
methods
pharmaceutical compositions
oral administration
Prior art date
Application number
DK91909171.0T
Other languages
Danish (da)
Inventor
Jean Pol Remol
Original Assignee
Europharmaceuticals Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Europharmaceuticals Sa filed Critical Europharmaceuticals Sa
Application granted granted Critical
Publication of DK0483320T3 publication Critical patent/DK0483320T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A pharmaceutical composition based on slow release granules designed to be orally administered. The composition includes a pharmacologically active substance and a pharmacologically acceptable excipient providing slow, even and stable release of said pharmacologically active substance after administration thereof. The excipient includes at least one mixture of low-viscosity ethylcellulose and high-viscosity ethylcellulose and the active substance is granulated with an alcoholic solution of the low-viscosity ethylcellulose, the weight ratio between the low- and high-viscosity ethylcellulose being from 1:5 to 1:20.
DK91909171.0T 1990-05-17 1991-05-16 Prolonged-release pharmaceutical compositions for oral administration and methods for their preparation DK0483320T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE9000524A BE1004243A3 (en) 1990-05-17 1990-05-17 Pharmaceutical sustained release type intended for oral administration and method of preparation.

Publications (1)

Publication Number Publication Date
DK0483320T3 true DK0483320T3 (en) 1995-01-30

Family

ID=3884799

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91909171.0T DK0483320T3 (en) 1990-05-17 1991-05-16 Prolonged-release pharmaceutical compositions for oral administration and methods for their preparation

Country Status (7)

Country Link
EP (1) EP0483320B1 (en)
AT (1) ATE110564T1 (en)
BE (1) BE1004243A3 (en)
DE (1) DE69103724T2 (en)
DK (1) DK0483320T3 (en)
ES (1) ES2064104T3 (en)
WO (1) WO1991017743A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4333190C2 (en) * 1993-09-29 1996-05-30 Korsatko Werner Univ Prof Dr E Bite-coated tablet with delayed release of active ingredient
US5679125A (en) * 1994-07-07 1997-10-21 Nikon Corporation Method for producing silica glass for use with light in a vacuum ultraviolet wavelength range
SI9500173B (en) * 1995-05-19 2002-02-28 Lek, Three-phase pharmaceutical form with constant and controlled release of amorphous active ingredient for single daily application
SE0200539D0 (en) * 2002-02-25 2002-02-25 Metcon Medicin Ab Granulation process and starch granulate

Also Published As

Publication number Publication date
ATE110564T1 (en) 1994-09-15
EP0483320B1 (en) 1994-08-31
EP0483320A1 (en) 1992-05-06
ES2064104T3 (en) 1995-01-16
DE69103724T2 (en) 1995-04-06
DE69103724D1 (en) 1994-10-06
WO1991017743A1 (en) 1991-11-28
BE1004243A3 (en) 1992-10-20

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