DK0393607T3 - Phenylcarboxylsyrederivater med en heteroring - Google Patents

Phenylcarboxylsyrederivater med en heteroring

Info

Publication number: DK0393607T3
Authority: DK; Denmark
Prior art keywords: heterocycle; acid derivatives; phenylcarboxylic acid; phenylcarboxylic; derivatives
Prior art date: 1989-04-19

Application number

DK90107302.3T

Other languages

English (en)

Inventor

Setsuro Fujii

Hiroyuki Kawamura

Shinichi Watanabe

Original Assignee

Otsuka Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-19

Filing date

1990-04-18

Publication date

1996-03-18

1990-04-18 Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd

1996-03-18 Application granted granted Critical

1996-03-18 Publication of DK0393607T3 publication Critical patent/DK0393607T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
- C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Diabetes (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Hematology (AREA)
Obesity (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Emergency Medicine (AREA)
Endocrinology (AREA)
Child & Adolescent Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Pyrrole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DK90107302.3T 1989-04-19 1990-04-18 Phenylcarboxylsyrederivater med en heteroring DK0393607T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP10143989		1989-04-19
JP3083990		1990-02-09

Publications (1)

Publication Number	Publication Date
DK0393607T3 true DK0393607T3 (da)	1996-03-18

Family

ID=26369254

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90107302.3T DK0393607T3 (da)	1989-04-19	1990-04-18	Phenylcarboxylsyrederivater med en heteroring

Country Status (7)

Country	Link
US (1)	US5145865A (da)
EP (1)	EP0393607B1 (da)
JP (1)	JP2657324B2 (da)
DE (1)	DE69025418T2 (da)
DK (1)	DK0393607T3 (da)
ES (1)	ES2087097T3 (da)
HU (1)	HU211654A9 (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
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DE4104870A1 (de) *	1991-02-17	1992-08-27	Bayer Ag	Verwendung von 3,(4)-substituierten pyrrolidinen als katalysatoren fuer das polyisocyanatpolyadditionsverfahren, verfahren zu ihrer herstellung sowie verfahren zur herstellung von polyurethan(harnstoff)en
CA2112129C (en) *	1992-04-30	1997-10-07	Shingo Yano	Oxazolidine derivative and pharmaceutically acceptable salt thereof
DE69327092T2 (de) *	1992-09-11	2000-05-25	Taiho Pharmaceutical Co. Ltd., Tokio/Tokyo	Optisch aktives 1-phenylpyrrolidonderivat und dessen herstellung
EP0716741B1 (en) *	1993-09-03	1997-12-10	Shell Internationale Researchmaatschappij B.V.	A method and apparatus for determining the concentration of a component present in a fluid stream in dispersed form
US5472958A (en) *	1994-08-29	1995-12-05	Abbott Laboratories	2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function
US5939439A (en) *	1996-12-30	1999-08-17	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
US6093737A (en) *	1996-12-30	2000-07-25	Merck & Co., Inc.	Inhibitors of farnesyl-protein transferase
US6127390A (en) *	1997-10-02	2000-10-03	Merck & Co., Inc.	Inhibitors of prenyl-protein transferase
JPH11113594A (ja)	1997-10-20	1999-04-27	Taiho Yakuhin Kogyo Kk	光学活性な１−（４−ｔ−ブチルフェニル）−５−オキソ−３−ピロリジンカルボン酸および／またはその鏡像対掌体エステルの製造方法
DK0916656T3 (da) *	1997-11-14	2004-01-05	Schering Ag	Fremgangsmåde til fremstilling af pyrrolidinoderivater
ATE311877T1 (de) *	1998-02-24	2005-12-15	Taiho Pharmaceutical Co Ltd	Lp(a)-mindernde mittel und inhibitoren der apoprotein (a) produktion
JP4467801B2 (ja) *	1998-10-27	2010-05-26	サントリーホールディングス株式会社	解糖系代謝調節剤の製造法
EP1318988A2 (en) *	2000-09-11	2003-06-18	Sepracor, Inc.	Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission)
US7067549B2 (en)	2001-12-31	2006-06-27	Actelion Pharmaceuticals Ag	Pyrrolidone carboxamides
MXPA04006458A (es) *	2001-12-31	2004-10-04	Actelion Pharmaceuticals Ltd	Pirrolidoncarboxamidas.
TWI286132B (en)	2002-09-20	2007-09-01	Hoffmann La Roche	4-pyrrolidino-phenyl-benzyl ether derivatives
US7148362B2 (en)	2003-09-18	2006-12-12	Hoffmann-La Roche Inc.	Process for the preparation of enantiopure pyrrolidin-2-one derivatives
WO2007061458A2 (en)	2005-11-23	2007-05-31	Epix Delaware, Inc.	S1p receptor modulating compounds and use thereof
US7919519B2 (en)	2005-11-23	2011-04-05	Epix Pharmaceuticals Inc.	S1P receptor modulating compounds and use thereof
AR060050A1 (es) *	2006-03-21	2008-05-21	Epix Delaware Inc	Compuestos moduladores del receptor de s1p y uso de los mismos
ATE505454T1 (de) *	2007-09-20	2011-04-15	Amgen Inc	1-(4-(4-benzylbenzamid)-benzyl)-azetidin-3- carboxylsäurederivate und entsprechende verbindungen als s1p-rezeptor-modulatoren zur behandlung von immunerkrankungen
KR20110022620A (ko)	2008-05-30	2011-03-07	다케다 야쿠힌 고교 가부시키가이샤	복소환 화합물
KR102296703B1 (ko)	2017-03-20	2021-09-01	포르마 세라퓨틱스 인크.	피루베이트 키나제 (pkr) 활성화제로서의 피롤로피롤 조성물
WO2020061255A1 (en)	2018-09-19	2020-03-26	Forma Therapeutics, Inc.	Activating pyruvate kinase r
WO2020061378A1 (en)	2018-09-19	2020-03-26	Forma Therapeutics, Inc.	Treating sickle cell disease with a pyruvate kinase r activating compound
US12128035B2 (en)	2021-03-19	2024-10-29	Novo Nordisk Health Care Ag	Activating pyruvate kinase R
CN115215787A (zh) *	2021-04-19	2022-10-21	中国科学院上海药物研究所	生长抑素受体5拮抗剂及其用途

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* Cited by examiner, † Cited by third party
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DE2460689C3 (de) *	1974-12-20	1980-06-26	Klinge Pharma Gmbh & Co, 8000 Muenchen	13-disubstituierte Propanol-(2)-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
US4109013A (en) *	1974-12-20	1978-08-22	Klinge Pharma Gmbh & Co.	Substituted propanol-(2) derivatives of hydroxamic acids and the use thereof as hypolipemic drugs
DE3718765A1 (de) *	1986-06-11	1987-12-17	Nippon Shinyaku Co Ltd	Benzoesaeurederivate

1990
- 1990-04-18 EP EP90107302A patent/EP0393607B1/en not_active Expired - Lifetime
- 1990-04-18 JP JP2103834A patent/JP2657324B2/ja not_active Expired - Fee Related
- 1990-04-18 ES ES90107302T patent/ES2087097T3/es not_active Expired - Lifetime
- 1990-04-18 DK DK90107302.3T patent/DK0393607T3/da active
- 1990-04-18 DE DE69025418T patent/DE69025418T2/de not_active Expired - Fee Related
- 1990-04-19 US US07/511,344 patent/US5145865A/en not_active Expired - Lifetime
1995
- 1995-06-30 HU HU95P/P00723P patent/HU211654A9/hu unknown

Also Published As

Publication number	Publication date
DE69025418D1 (de)	1996-03-28
JP2657324B2 (ja)	1997-09-24
US5145865A (en)	1992-09-08
EP0393607A2 (en)	1990-10-24
DE69025418T2 (de)	1996-11-14
JPH03275666A (ja)	1991-12-06
ES2087097T3 (es)	1996-07-16
EP0393607A3 (en)	1992-01-22
HU211654A9 (en)	1995-12-28
EP0393607B1 (en)	1996-02-21

Publication	Publication Date	Title
DK0393607T3 (da)	1996-03-18	Phenylcarboxylsyrederivater med en heteroring
DK286389A (da)	1989-12-14	Aminosyrederivater
DE10075034I1 (de)	2001-05-23	Insulinderivate
DK96889D0 (da)	1989-02-28	Aminosyrederivater
HU9902539D0 (en)	1999-10-28	Enantiomere cyclopentene derivatives
DK351789A (da)	1990-01-19	Furanderivater
DE68925161D1 (de)	1996-02-01	Alkylavermectin-Derivate
DE68926763D1 (de)	1996-08-08	Eingedickte Formmassen
DE68927948D1 (de)	1997-05-15	Trehalosderivate
DK491389A (da)	1990-04-07	Substituerede 9h-purinderivater
DK19789D0 (da)	1989-01-17	Dehydrocholcalciferolderivater
DE68927657D1 (de)	1997-02-27	Butynylaminderivate
DK301789D0 (da)	1989-06-19	Neplanocin-derivater
DK300887A (da)	1987-12-14	Dihydropyridinderivater
DK486089D0 (da)	1989-10-03	Pyranobenzoxadiazolderivater
DK10190D0 (da)	1990-01-12	1,1-dioxo-cephem-4-carbothiolsyrederivater
NO894592D0 (no)	1989-11-17	Pyrrolidon-2-karboksylsyre-derivater med psykotropisk virkning.
KR900700568A (ko)	1990-08-16	2,3-디플루오로벤조산 유도체
FR2594306B1 (fr)	1988-08-05	Bracelet non extensible a charnieres apparentes
DK160389A (da)	1989-10-05	Aryldionderivater
DK350989A (da)	1990-01-16	Tiazolderivater
DK670589A (da)	1990-06-30	Carboxylsyrederivater
ATA155589A (de)	1994-02-15	Mitomycinphosphat-derivate
DK324489D0 (da)	1989-06-29	Substituerede azacyclohexylderivater
DK538689A (da)	1990-05-01	Penicillansyrederivater