DE69324910D1 - Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten - Google Patents

Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten

Info

Publication number: DE69324910D1
Authority: DE; Germany
Prior art keywords: angiotensin; receptor antagonists; triazolopyrimidine derivatives; derivatives; treatment
Prior art date: 1992-02-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69324910T

Other languages

English (en)

Other versions

DE69324910T2 (de

Inventor

Nicole Bru-Magniez

Timur Guengoer

Jean-Marie Teulon

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

UNION PHARMA SCIENT APPL

UPSA SAS

Original Assignee

UNION PHARMA SCIENT APPL

UPSA SAS

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-24

Filing date

1993-02-18

Publication date

1999-06-17

1992-02-24 Priority claimed from FR9202109A external-priority patent/FR2687676B1/fr

1993-02-18 Application filed by UNION PHARMA SCIENT APPL, UPSA SAS filed Critical UNION PHARMA SCIENT APPL

1999-06-17 Application granted granted Critical

1999-06-17 Publication of DE69324910D1 publication Critical patent/DE69324910D1/de

1999-10-21 Publication of DE69324910T2 publication Critical patent/DE69324910T2/de

2013-02-19 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

DE69324910T 1992-02-24 1993-02-18 Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten Expired - Lifetime DE69324910T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9202109A FR2687676B1 (fr)	1992-02-24	1992-02-24	Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.
FR9205417A FR2687677B1 (fr)	1992-02-24	1992-04-30	Nouveaux derives de polyazaindenes antagonistes des recepteurs a l'angiotensine ii ; leurs procedes de preparation, compositions pharmaceutiques les contenant.
PCT/FR1993/000161 WO1993017024A1 (fr)	1992-02-24	1993-02-18	Derives de triazolopyrimidines antagonistes des recepteurs a l'angiotensine ii

Publications (2)

Publication Number	Publication Date
DE69324910D1 true DE69324910D1 (de)	1999-06-17
DE69324910T2 DE69324910T2 (de)	1999-10-21

Family

ID=26229283

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69324910T Expired - Lifetime DE69324910T2 (de)	1992-02-24	1993-02-18	Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten

Country Status (19)

Country	Link
EP (2)	EP0628046B1 (de)
JP (2)	JPH07504177A (de)
KR (2)	KR100272922B1 (de)
AT (1)	ATE179979T1 (de)
AU (2)	AU668544B2 (de)
CA (2)	CA2128876C (de)
CZ (2)	CZ282075B6 (de)
DE (1)	DE69324910T2 (de)
EE (2)	EE03046B1 (de)
ES (1)	ES2133390T3 (de)
FI (2)	FI943808A (de)
FR (1)	FR2687677B1 (de)
HU (2)	HUT70953A (de)
MD (2)	MD553G2 (de)
NZ (2)	NZ249509A (de)
RU (1)	RU2116308C1 (de)
SK (2)	SK99894A3 (de)
TW (2)	TW221438B (de)
WO (2)	WO1993017024A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5389632A (en) *	1992-02-24	1995-02-14	Laboratoires Upsa	Pyrazolopyrimidine derivatives which are angiotensin II receptor antagonists
IT1263804B (it) *	1993-01-22	1996-09-03	Luso Farmaco Inst	Derivati pirimidinonici fusi con eterocicli azotati ad attivita' a ii antagonista
US5571813A (en) *	1993-06-10	1996-11-05	Beiersdorf-Lilly Gmbh	Fused pyrimidine compounds and their use as pharmaceuticals
US20080188494A1 (en) *	2005-04-25	2008-08-07	Basf Aktiengesellschaft	Use Of 5-Alkyl-6-Phenylalkyl-7-Aminoazolopyrimidines, Novel Azolopyrimidines, Processes For Their Preparation And Compositions Comprising Them
WO2008003753A1 (en) *	2006-07-07	2008-01-10	Biovitrum Ab (Publ)	Pyrazolo [1,5-a] pyrimidine analogs for use as inhibitors of stearoyl-coa desaturase (scd) activity
DE102006039255A1 (de) *	2006-08-17	2008-02-21	Bayer Cropscience Ag	Insektizide heterocyclische Carbonsäurederivate
UY32409A (es) *	2009-01-30	2010-08-31	Takeda Pharmaceutical	Compuesto de anillo fusionado y su uso
JP2013538838A (ja)	2010-09-27	2013-10-17	プロクシマゲンリミテッド	７−ヒドロキシ−ピラゾロ［１，５−ａ］ピリミジン化合物およびｃｃｒ２レセプターアンタゴニストとしてのその使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL94390A (en) *	1989-05-30	1996-03-31	Merck & Co Inc	The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
EP0522038A4 (en) *	1990-03-30	1993-05-26	Merck & Co. Inc.	Substituted pyrimidines, pyrimidinones and pyridopyrimidines
FR2678618B1 (fr) *	1991-07-05	1993-11-05	Upsa Laboratoires	Nouveaux derives de triazolo pyrimidine antagonistes des recepteurs a l'angiotensine ii; leurs procedes de preparation, compositions pharmaceutiques les contenant.

1992
- 1992-04-30 FR FR9205417A patent/FR2687677B1/fr not_active Expired - Lifetime
1993
- 1993-02-18 AU AU36358/93A patent/AU668544B2/en not_active Expired
- 1993-02-18 HU HU9402429A patent/HUT70953A/hu unknown
- 1993-02-18 SK SK998-94A patent/SK99894A3/sk unknown
- 1993-02-18 JP JP5514580A patent/JPH07504177A/ja active Pending
- 1993-02-18 WO PCT/FR1993/000161 patent/WO1993017024A1/fr active IP Right Grant
- 1993-02-18 EP EP93905402A patent/EP0628046B1/de not_active Expired - Lifetime
- 1993-02-18 RU RU94040854A patent/RU2116308C1/ru active
- 1993-02-18 HU HU9402430A patent/HU220392B/hu unknown
- 1993-02-18 EP EP93905401A patent/EP0628045A1/de not_active Ceased
- 1993-02-18 AU AU36357/93A patent/AU668139B2/en not_active Expired
- 1993-02-18 NZ NZ249509A patent/NZ249509A/en not_active IP Right Cessation
- 1993-02-18 CA CA002128876A patent/CA2128876C/en not_active Expired - Lifetime
- 1993-02-18 CZ CZ942044A patent/CZ282075B6/cs not_active IP Right Cessation
- 1993-02-18 CA CA002128871A patent/CA2128871A1/en not_active Abandoned
- 1993-02-18 ES ES93905402T patent/ES2133390T3/es not_active Expired - Lifetime
- 1993-02-18 DE DE69324910T patent/DE69324910T2/de not_active Expired - Lifetime
- 1993-02-18 NZ NZ249508A patent/NZ249508A/en not_active IP Right Cessation
- 1993-02-18 KR KR1019940702948A patent/KR100272922B1/ko not_active IP Right Cessation
- 1993-02-18 CZ CZ942045A patent/CZ204594A3/cs unknown
- 1993-02-18 SK SK997-94A patent/SK280343B6/sk not_active IP Right Cessation
- 1993-02-18 JP JP51458193A patent/JP3372040B2/ja not_active Expired - Lifetime
- 1993-02-18 WO PCT/FR1993/000160 patent/WO1993017023A1/fr not_active Application Discontinuation
- 1993-02-18 AT AT93905402T patent/ATE179979T1/de active
- 1993-02-24 TW TW082101329A patent/TW221438B/zh not_active IP Right Cessation
- 1993-02-24 TW TW082101333A patent/TW222275B/zh not_active IP Right Cessation
1994
- 1994-08-19 FI FI943808A patent/FI943808A/fi not_active Application Discontinuation
- 1994-08-19 FI FI943807A patent/FI943807A/fi not_active Application Discontinuation
- 1994-08-24 KR KR1019940702947A patent/KR950700302A/ko not_active Application Discontinuation
- 1994-11-22 EE EE9400441A patent/EE03046B1/xx unknown
- 1994-11-22 EE EE9400440A patent/EE03045B1/xx unknown
- 1994-12-30 MD MD95-0085A patent/MD553G2/ro active IP Right Grant
- 1994-12-30 MD MD95-0112A patent/MD554G2/ro active IP Right Grant

Also Published As

Publication number	Publication date
FI943808A0 (fi)	1994-08-19
RU94040854A (ru)	1996-08-10
CA2128876A1 (en)	1993-09-02
DE69324910T2 (de)	1999-10-21
EP0628046A1 (de)	1994-12-14
JPH07504177A (ja)	1995-05-11
AU668544B2 (en)	1996-05-09
WO1993017024A1 (fr)	1993-09-02
AU3635793A (en)	1993-09-13
FI943808A (fi)	1994-10-24
FR2687677B1 (fr)	1996-10-11
WO1993017023A1 (fr)	1993-09-02
CZ204594A3 (en)	1994-12-15
CZ282075B6 (cs)	1997-05-14
SK99794A3 (en)	1995-04-12
FR2687677A1 (fr)	1993-08-27
ES2133390T3 (es)	1999-09-16
EE03045B1 (et)	1997-10-15
SK99894A3 (en)	1995-04-12
HU9402430D0 (en)	1994-10-28
MD554G2 (ro)	1997-01-31
KR950700302A (ko)	1995-01-16
HU9402429D0 (en)	1994-10-28
MD554F1 (en)	1996-05-31
CA2128876C (en)	2004-02-03
AU668139B2 (en)	1996-04-26
EE03046B1 (et)	1997-10-15
HUT70949A (en)	1995-11-28
ATE179979T1 (de)	1999-05-15
MD553G2 (ro)	1996-12-31
RU2116308C1 (ru)	1998-07-27
HU220392B (hu)	2002-01-28
SK280343B6 (sk)	1999-12-10
CA2128871A1 (en)	1993-09-02
HUT70953A (en)	1995-11-28
NZ249508A (en)	1996-07-26
AU3635893A (en)	1993-09-13
FI943807A0 (fi)	1994-08-19
TW221438B (de)	1994-03-01
KR950700303A (ko)	1995-01-16
CZ204494A3 (en)	1994-12-15
NZ249509A (en)	1996-06-25
EP0628045A1 (de)	1994-12-14
JP3372040B2 (ja)	2003-01-27
JPH07504178A (ja)	1995-05-11
KR100272922B1 (ko)	2001-02-01
EP0628046B1 (de)	1999-05-12
FI943807A (fi)	1994-10-24
MD553F1 (en)	1996-05-31
TW222275B (de)	1994-04-11

Publication	Publication Date	Title
NL300006I1 (nl)	2000-07-03	Imidazolylalkeenzuurderivaten.
NO872863L (no)	1988-01-12	Analogifremgangsmte for fremstilling av terapeutiske imidazoler som blokkerer angiotensin-ii-reseptorer.
ES2062403T3 (es)	1994-12-16	5-((tetrazolil)-alquenil)-imidazoles sustituidos.
LV12047A (lv)	1998-05-20	Kondenseti pirimidina atvasinajumi un to lietosana par angiotenzina II antagonistiem
CA2072233A1 (en)	1993-01-06	Triazolopyrimidine derivatives which are angiotensin ii receptor antagonists; processes for preparing them and pharmaceutical compositions containing them
ATE119524T1 (de)	1995-03-15	Substituierte n-(imidazolyl)alkyl-alanin- derivate.
DE69324910D1 (de)	1999-06-17	Triazolopyrimidinderivate als angiotensin-ii rezeptor antagonisten
FI943730A (fi)	1994-08-12	Menetelmä angiotensiini-II-antagonistina aktiivisen 3-(2'-N-bentsoyylisulfonamido-bifen-4-yyli)metyyli-5,7-dimetyyli-2-etyyli-3H-imidatso/4,5-b/pyridiinin valmistamiseksi

Legal Events

Date	Code	Title	Description
2000-06-08	8364	No opposition during term of opposition
2013-02-19	R071	Expiry of right	Ref document number: 628046 Country of ref document: EP

Date

Code

Title

Description

2000-06-08

8364

No opposition during term of opposition

2013-02-19

R071

Expiry of right

Ref document number: 628046

Country of ref document: EP