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DE69324442D1 - Arznei Zusammensetzungen, die ein Arzneimittel, ein quervernetztes Polymer, ein Öl, und ein grenzflächenaktives Mittel enthalten - Google Patents

Arznei Zusammensetzungen, die ein Arzneimittel, ein quervernetztes Polymer, ein Öl, und ein grenzflächenaktives Mittel enthalten

Info

Publication number
DE69324442D1
DE69324442D1 DE69324442T DE69324442T DE69324442D1 DE 69324442 D1 DE69324442 D1 DE 69324442D1 DE 69324442 T DE69324442 T DE 69324442T DE 69324442 T DE69324442 T DE 69324442T DE 69324442 D1 DE69324442 D1 DE 69324442D1
Authority
DE
Germany
Prior art keywords
drug
linked polymer
oil
cross
surfactant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69324442T
Other languages
English (en)
Other versions
DE69324442T2 (de
Inventor
Fabio Carli
Daniela Lombardi
Pierandrea Esposito
Luca Dobetti
Luigi Boltri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Vectorpharma International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma International SpA filed Critical Vectorpharma International SpA
Publication of DE69324442D1 publication Critical patent/DE69324442D1/de
Application granted granted Critical
Publication of DE69324442T2 publication Critical patent/DE69324442T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
DE69324442T 1992-11-13 1993-11-11 Arznei Zusammensetzungen, die ein Arzneimittel, ein quervernetztes Polymer, ein Öl, und ein grenzflächenaktives Mittel enthalten Expired - Lifetime DE69324442T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI922603A IT1256386B (it) 1992-11-13 1992-11-13 Composizioni farmaceutiche comprendenti un farmaco,una sostanza polimerica reticolata,un olio ed un agente tensioattivo

Publications (2)

Publication Number Publication Date
DE69324442D1 true DE69324442D1 (de) 1999-05-20
DE69324442T2 DE69324442T2 (de) 1999-08-05

Family

ID=11364286

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69324442T Expired - Lifetime DE69324442T2 (de) 1992-11-13 1993-11-11 Arznei Zusammensetzungen, die ein Arzneimittel, ein quervernetztes Polymer, ein Öl, und ein grenzflächenaktives Mittel enthalten

Country Status (7)

Country Link
US (1) US6107276A (de)
EP (1) EP0598337B1 (de)
AT (1) ATE178787T1 (de)
DE (1) DE69324442T2 (de)
ES (1) ES2132162T3 (de)
GR (1) GR3030732T3 (de)
IT (1) IT1256386B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL115445A (en) * 1994-10-17 1999-08-17 Akzo Nobel Nv Solid pharmaceutical compositions comprising low dosage active ingredient oil and excipient capable of binding water and their preparation
NL1003503C2 (nl) * 1996-07-04 1998-01-07 Negma Steba International Dev Farmaceutische samenstelling voor orale toediening.
HUP9603364A2 (hu) * 1996-12-06 1998-12-28 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Ipriflavont tartalmazó csonthiány pótlására szolgáló gyógyászati készítmény és eljárás előállítására
AR012627A1 (es) 1997-04-29 2000-11-08 Sherman Bernard Charles Pre-concentrado de emulsion que comprende una ciclosporina y monoglicerido acetilado
NZ314702A (en) * 1997-04-29 1998-07-28 Bernard Charles Sherman Pharmaceutical composition comprising a cyclosporin in a solvent system of acetylated monoglycerides and a surfactant and optionally a hydrophilic solvent
IT1293835B1 (it) * 1997-08-08 1999-03-10 Foscama Biomed Chim Farma Composizioni farmaceutiche orali in forma solida a cessione modulata contenenti nicorandil e procedimento per la loro preparazione
US6063762A (en) * 1997-12-05 2000-05-16 Chong Kun Dang Corp. Cyclosporin-containing microemulsion preconcentrate composition
IL145140A0 (en) * 1999-03-24 2002-06-30 Fmc Corp Improved aqueous solubility pharmaceutical formulations
NZ530701A (en) * 1999-06-04 2005-09-30 Alza Corp Implantable gel compositions comprising compressed particles including the active agent in a bioerodible gel
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
DE10046541A1 (de) * 2000-09-19 2002-03-28 Knoll Ag Mechanisch stabile darreichungsformen, enthaltend Ubichinone
US6300377B1 (en) * 2001-02-22 2001-10-09 Raj K. Chopra Coenzyme Q products exhibiting high dissolution qualities
WO2003007928A1 (fr) * 2001-07-17 2003-01-30 Idemitsu Kosan Co., Ltd. Medicaments prophylactiques contre l'ascite pour la volaille
FR2832065B1 (fr) * 2001-11-13 2004-11-05 Besins Int Belgique Composition pharmaceutique a base de progesterone micronisee son procede de preparation et ses utilisations
JP4780522B2 (ja) * 2003-11-14 2011-09-28 味の素株式会社 フェニルアラニン誘導体の固体分散体または固体分散体医薬製剤
US20070196396A1 (en) * 2004-02-11 2007-08-23 Rubicon Research Private Limited Controlled release pharmaceutical compositions with improved bioavailability
KR20170123724A (ko) 2006-03-28 2017-11-08 자블린 파머슈티칼스 인코포레이티드 저 투여량의 디클로페낙 및 베타-사이클로덱스트린 제형
WO2009040776A1 (en) 2007-09-27 2009-04-02 Wockhardt Research Centre Self-emulsifying pharmaceutical compositions of rhein or diacerein
SG10202010355PA (en) * 2010-03-12 2020-11-27 Berg Llc Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof
IE20100799A1 (en) * 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
EA201490047A1 (ru) 2011-06-17 2014-08-29 Берг Ллк Ингаляционные фармацевтические композиции
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US9687475B1 (en) 2016-03-24 2017-06-27 Ezra Pharma Llc Extended release pharmaceutical formulations with controlled impurity levels
US9675585B1 (en) 2016-03-24 2017-06-13 Ezra Pharma Extended release pharmaceutical formulations
US10286077B2 (en) 2016-04-01 2019-05-14 Therapeuticsmd, Inc. Steroid hormone compositions in medium chain oils
JP2019513709A (ja) 2016-04-01 2019-05-30 セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. ステロイドホルモン薬学的組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3224619A1 (de) * 1981-07-14 1983-05-19 Freund Industrial Co., Ltd., Tokyo Orale pharmazeutische zusammensetzung
DE3270785D1 (en) * 1981-10-29 1986-05-28 Bayer Ag Process for preparing solid fast-releasing drug formulations of dihydropyridines
GB8403359D0 (en) * 1984-02-08 1984-03-14 Erba Farmitalia Pharmaceutical compositions
DE3524572A1 (de) * 1985-07-10 1987-01-15 Thomae Gmbh Dr K Feste arzneimittelformen zur peroralen anwendung enthaltend 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin und verfahren zu ihrer herstellung
DE69129918T2 (de) * 1990-03-23 1999-02-04 Yoshitomi Pharmaceutical Industries, Ltd., Osaka Ein in Wasser schwerlösliches Arzneimittel enthaltende pharmazeutische Zubereitung

Also Published As

Publication number Publication date
EP0598337A3 (de) 1995-06-14
ES2132162T3 (es) 1999-08-16
US6107276A (en) 2000-08-22
EP0598337A2 (de) 1994-05-25
ITMI922603A1 (it) 1994-05-13
ATE178787T1 (de) 1999-04-15
GR3030732T3 (en) 1999-11-30
DE69324442T2 (de) 1999-08-05
IT1256386B (it) 1995-12-04
ITMI922603A0 (it) 1992-11-13
EP0598337B1 (de) 1999-04-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: EURAND INTERNATIONAL S.P.A., MAILAND/MILANO, IT