DE69320542D1 - Pyrrolothienopyrazin-Verbindungen als 5HT3-Rezeptoren-Antagonisten - Google Patents

Pyrrolothienopyrazin-Verbindungen als 5HT3-Rezeptoren-Antagonisten

Info

Publication number: DE69320542D1
Authority: DE; Germany
Prior art keywords: compounds; pyrrolothienopyrazine; receptor antagonists; medicaments; image
Prior art date: 1992-06-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE69320542T

Other languages

English (en)

Other versions

DE69320542T2 (de

Inventor

Sylvain Rault

Jean-Charles Lancelot

Vincente Juan-Carlos Pilo

Max Robba

Beatrice Guardiola-Lemaitre

Pierre Renard

Gerard Adam

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

ADIR SARL

Original Assignee

ADIR SARL

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-06-05

Filing date

1993-06-03

Publication date

1998-10-01

1993-06-03 Application filed by ADIR SARL filed Critical ADIR SARL

1998-10-01 Application granted granted Critical

1998-10-01 Publication of DE69320542D1 publication Critical patent/DE69320542D1/de

1999-04-29 Publication of DE69320542T2 publication Critical patent/DE69320542T2/de

2013-06-04 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
General Health & Medical Sciences (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Neurology (AREA)
Public Health (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Pain & Pain Management (AREA)
Anesthesiology (AREA)
Otolaryngology (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DE69320542T 1992-06-05 1993-06-03 Pyrrolothienopyrazin-Verbindungen als 5HT3-Rezeptoren-Antagonisten Expired - Fee Related DE69320542T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9206800A FR2691967B1 (fr)	1992-06-05	1992-06-05	Nouveaux composes pyrrolothienopyraziniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number	Publication Date
DE69320542D1 true DE69320542D1 (de)	1998-10-01
DE69320542T2 DE69320542T2 (de)	1999-04-29

Family

ID=9430449

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69320542T Expired - Fee Related DE69320542T2 (de)	1992-06-05	1993-06-03	Pyrrolothienopyrazin-Verbindungen als 5HT3-Rezeptoren-Antagonisten

Country Status (11)

Country	Link
EP (1)	EP0573360B1 (de)
JP (1)	JPH0794460B2 (de)
AT (1)	ATE170187T1 (de)
AU (1)	AU659738B2 (de)
CA (1)	CA2097779A1 (de)
DE (1)	DE69320542T2 (de)
DK (1)	DK0573360T3 (de)
ES (1)	ES2123038T3 (de)
FR (1)	FR2691967B1 (de)
NZ (1)	NZ247791A (de)
ZA (1)	ZA933942B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US10040802B2 (en)	2015-03-12	2018-08-07	Merck Sharp & Dohme Corp.	Thienopyrazine inhibitors of IRAK4 activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4997433A (en) *	1990-01-16	1991-03-05	Marlowe Goble E	Endosteal fixation stud and system
FR2659332B1 (fr) *	1990-03-08	1994-04-29	Adit Et Cie	Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2660310B1 (fr) *	1990-03-27	1992-06-05	Adir	Nouveaux derives de la 4h-pyrrolo[1,2a] thieno[2,3-f] diazepine[1,4], leur procede de preparation et les compositions pharmaceutiques les renfermant.

1992
- 1992-06-05 FR FR9206800A patent/FR2691967B1/fr not_active Expired - Fee Related
1993
- 1993-06-03 DK DK93401416T patent/DK0573360T3/da active
- 1993-06-03 AT AT93401416T patent/ATE170187T1/de not_active IP Right Cessation
- 1993-06-03 EP EP93401416A patent/EP0573360B1/de not_active Expired - Lifetime
- 1993-06-03 ES ES93401416T patent/ES2123038T3/es not_active Expired - Lifetime
- 1993-06-03 DE DE69320542T patent/DE69320542T2/de not_active Expired - Fee Related
- 1993-06-04 ZA ZA933942A patent/ZA933942B/xx unknown
- 1993-06-04 JP JP5134922A patent/JPH0794460B2/ja not_active Expired - Lifetime
- 1993-06-04 CA CA002097779A patent/CA2097779A1/fr not_active Abandoned
- 1993-06-04 AU AU40059/93A patent/AU659738B2/en not_active Ceased
- 1993-06-04 NZ NZ247791A patent/NZ247791A/en unknown

Also Published As

Publication number	Publication date
AU659738B2 (en)	1995-05-25
FR2691967B1 (fr)	1995-06-09
DK0573360T3 (da)	1999-05-25
JPH0794460B2 (ja)	1995-10-11
EP0573360B1 (de)	1998-08-26
AU4005993A (en)	1993-12-09
DE69320542T2 (de)	1999-04-29
EP0573360A1 (de)	1993-12-08
CA2097779A1 (fr)	1993-12-06
ATE170187T1 (de)	1998-09-15
ES2123038T3 (es)	1999-01-01
ZA933942B (en)	1993-12-30
NZ247791A (en)	1994-12-22
JPH06172363A (ja)	1994-06-21
FR2691967A1 (fr)	1993-12-10

Publication	Publication Date	Title
ES2081187T3 (es)	1996-02-16	Nuevas naftil-alquil-aminas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
DK0580502T3 (da)	1999-05-31	3-(hydroxybenzylidenyl)-indolin-2-oner og farmaceutiske sammensætninger indeholdende disse
ATE165601T1 (de)	1998-05-15	Benzopyran-verbindungen, verfahren zu ihrer herstellung und ihre verwendung als zellenschutzmittel
NO870199D0 (no)	1987-01-16	Alalogifremgangsmaate for fremstilling av nye, terapeutisk virksomme dihydrobenzofuran- og chroman-carboxamidderivater.
ES2077473T3 (es)	1995-11-16	Nuevos compuestos tiocromanicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
ATE170187T1 (de)	1998-09-15	Pyrrolothienopyrazin-verbindungen als 5ht3- rezeptoren-antagonisten
ES2123728T3 (es)	1999-01-16	Derivados de pirrolo-pirazina de actividad 5-ht3.
ES2076054T3 (es)	1995-10-16	Nuevas amino-alquil-cromonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.

Legal Events

Date	Code	Title	Description
1999-09-23	8364	No opposition during term of opposition
2001-08-09	8339	Ceased/non-payment of the annual fee