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DE69113991D1 - Impfstoff. - Google Patents

Impfstoff.

Info

Publication number
DE69113991D1
DE69113991D1 DE69113991T DE69113991T DE69113991D1 DE 69113991 D1 DE69113991 D1 DE 69113991D1 DE 69113991 T DE69113991 T DE 69113991T DE 69113991 T DE69113991 T DE 69113991T DE 69113991 D1 DE69113991 D1 DE 69113991D1
Authority
DE
Germany
Prior art keywords
detoxified
pertussis toxin
vaccine
reversion
toxicity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69113991T
Other languages
English (en)
Other versions
DE69113991T2 (de
Inventor
Carine Capiau
Jean Petre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Original Assignee
SmithKline Beecham Biologicals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Biologicals SA filed Critical SmithKline Beecham Biologicals SA
Publication of DE69113991D1 publication Critical patent/DE69113991D1/de
Application granted granted Critical
Publication of DE69113991T2 publication Critical patent/DE69113991T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/099Bordetella
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K2039/10Brucella; Bordetella, e.g. Bordetella pertussis; Not used, see subgroups

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE69113991T 1990-02-12 1991-02-07 Impfstoff. Expired - Lifetime DE69113991T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47909890A 1990-02-12 1990-02-12
PCT/EP1991/000257 WO1991012020A1 (en) 1990-02-12 1991-02-07 Novel vaccine and method therefor

Publications (2)

Publication Number Publication Date
DE69113991D1 true DE69113991D1 (de) 1995-11-23
DE69113991T2 DE69113991T2 (de) 1996-03-21

Family

ID=23902647

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69113991T Expired - Lifetime DE69113991T2 (de) 1990-02-12 1991-02-07 Impfstoff.

Country Status (17)

Country Link
EP (1) EP0515415B1 (de)
JP (1) JP3035712B2 (de)
KR (1) KR100202052B1 (de)
AT (1) ATE129159T1 (de)
AU (1) AU646019B2 (de)
CA (1) CA2075711C (de)
CY (1) CY1935A (de)
DE (1) DE69113991T2 (de)
DK (1) DK0515415T3 (de)
ES (1) ES2080941T3 (de)
GR (1) GR3018440T3 (de)
HK (1) HK1004524A1 (de)
IE (1) IE70672B1 (de)
NZ (1) NZ237069A (de)
PT (1) PT96723B (de)
WO (1) WO1991012020A1 (de)
ZA (1) ZA91947B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0835663T3 (da) 1992-05-23 2010-02-01 Glaxosmithkline Biolog Sa Kombinerede vacciner omfattende Hepatitis B overfladeantigen og andre antigener
GB9216351D0 (en) * 1992-07-31 1992-09-16 Wellcome Found Vaccine production
ATE452651T1 (de) * 1998-09-01 2010-01-15 Merrion Res Iii Ltd Orale impfstoff-zusammensetzung
AU769539B2 (en) * 1999-01-29 2004-01-29 Zoetis Services Llc Adjuvants for use in vaccines
GB0313916D0 (en) 2003-06-16 2003-07-23 Glaxosmithkline Biolog Sa Vaccine composition
BR112014017898B1 (pt) 2012-02-01 2021-10-13 Glaxosmithkline Biologicals S.A. Processo de fermentação
SG11201500573RA (en) 2012-08-06 2015-02-27 Glaxosmithkline Biolog Sa Method for eliciting in infants an immune response against rsv and b. pertussis
US20140037680A1 (en) 2012-08-06 2014-02-06 Glaxosmithkline Biologicals, S.A. Novel method
CN105007936B (zh) 2013-03-08 2018-10-02 扬森疫苗与预防公司 无细胞百日咳疫苗
US9849066B2 (en) 2013-04-24 2017-12-26 Corning Incorporated Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
WO2015018806A1 (en) 2013-08-05 2015-02-12 Glaxosmithkline Biologicals S.A. Combination immunogenic compositions

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4075321A (en) * 1973-05-04 1978-02-21 Agence Nationale De Valorisation De La Recherche (Anvar) Vaccines, the process for preparing the same and the applications thereof
JPS5750925A (en) * 1980-09-12 1982-03-25 Takeda Chem Ind Ltd Preparation of pertussis toxoid
GB8601279D0 (en) * 1986-01-20 1986-02-26 Public Health Lab Service Purification of pertussis antigens
US4888169A (en) * 1986-10-14 1989-12-19 Norden Laboratories, Inc. Bordetella Bronchiseptica vaccine
AU5027890A (en) * 1989-02-10 1990-09-05 Genesit Oy A method for producing pertussis toxin subunits

Also Published As

Publication number Publication date
EP0515415B1 (de) 1995-10-18
PT96723A (pt) 1991-10-31
WO1991012020A1 (en) 1991-08-22
KR100202052B1 (ko) 1999-06-15
JP3035712B2 (ja) 2000-04-24
IE70672B1 (en) 1996-12-11
NZ237069A (en) 1993-07-27
JPH05503936A (ja) 1993-06-24
KR920703099A (ko) 1992-12-17
DE69113991T2 (de) 1996-03-21
EP0515415A1 (de) 1992-12-02
CA2075711C (en) 2000-11-07
CY1935A (en) 1991-02-07
CA2075711A1 (en) 1991-08-13
GR3018440T3 (en) 1996-03-31
HK1004524A1 (en) 1998-11-27
ZA91947B (en) 1992-01-29
IE910424A1 (en) 1991-08-14
AU646019B2 (en) 1994-02-03
PT96723B (pt) 1998-07-31
ES2080941T3 (es) 1996-02-16
ATE129159T1 (de) 1995-11-15
AU7211091A (en) 1991-09-03
DK0515415T3 (da) 1995-11-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition