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DE69110107D1 - Verfahren zur Herstellung von 3-Alkoxymethyl Cephalosporinderivate. - Google Patents

Verfahren zur Herstellung von 3-Alkoxymethyl Cephalosporinderivate.

Info

Publication number
DE69110107D1
DE69110107D1 DE69110107T DE69110107T DE69110107D1 DE 69110107 D1 DE69110107 D1 DE 69110107D1 DE 69110107 T DE69110107 T DE 69110107T DE 69110107 T DE69110107 T DE 69110107T DE 69110107 D1 DE69110107 D1 DE 69110107D1
Authority
DE
Germany
Prior art keywords
compound
formula
alkoxymethyl
preparation
cephalosporin derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69110107T
Other languages
English (en)
Other versions
DE69110107T2 (de
Inventor
Yukio Hirayama
Syuji Sayama
Kiyomi Yamaguchi
Shigeru Miyamoto
Yasuo Takahashi
Keisuke Kato
Tomio Sasao
Kiyoshi Iijima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of DE69110107D1 publication Critical patent/DE69110107D1/de
Application granted granted Critical
Publication of DE69110107T2 publication Critical patent/DE69110107T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/18—7-Aminocephalosporanic or substituted 7-aminocephalosporanic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69110107T 1990-11-07 1991-11-06 Verfahren zur Herstellung von 3-Alkoxymethyl Cephalosporinderivate. Expired - Fee Related DE69110107T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP30207190 1990-11-07

Publications (2)

Publication Number Publication Date
DE69110107D1 true DE69110107D1 (de) 1995-07-06
DE69110107T2 DE69110107T2 (de) 1996-02-01

Family

ID=17904568

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69110107T Expired - Fee Related DE69110107T2 (de) 1990-11-07 1991-11-06 Verfahren zur Herstellung von 3-Alkoxymethyl Cephalosporinderivate.

Country Status (10)

Country Link
US (1) US5451675A (de)
EP (1) EP0485204B1 (de)
JP (1) JP3206821B2 (de)
KR (1) KR0140196B1 (de)
AT (1) ATE123286T1 (de)
DE (1) DE69110107T2 (de)
DK (1) DK0485204T3 (de)
ES (1) ES2075365T3 (de)
HK (1) HK1005452A1 (de)
IE (1) IE68511B1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT401177B (de) * 1993-10-22 1996-07-25 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3-cephem-4-carbonsäure-derivaten
KR100343434B1 (ko) * 1999-10-13 2002-07-11 민경윤 7-아미노-3-메톡시메틸-3-세펨-4-카복실산의 제조방법
IN192344B (de) * 2001-01-30 2004-04-10 Ranbaxy Lab Ltd
EP2758407A1 (de) 2011-09-20 2014-07-30 Dhanuka Laboratories Ltd. Verbessertes verfahren für cefpodoximsäure
WO2017153824A1 (en) 2016-03-07 2017-09-14 Dhanuka Laboratories Ltd. A process for alkylating the hydroxymethyl group at position -3 of cephalosporins
CN105669701A (zh) * 2016-03-22 2016-06-15 陕西思尔生物科技有限公司 一种头孢泊肟酯中间体的合成方法
CN106478666B (zh) * 2016-09-22 2018-07-31 湖北凌晟药业有限公司 7-氨基-3-甲氧甲基-3-头孢烯-4-羧酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5896091A (ja) * 1981-12-01 1983-06-07 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリン類の製造法
JPS59163387A (ja) * 1983-03-07 1984-09-14 Sankyo Co Ltd ３−アルコキシメチルセフアロスポリンの製造方法
AT384222B (de) * 1985-06-03 1987-10-12 Biochemie Gmbh Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren
DE3789412T2 (de) * 1986-10-02 1994-06-30 Asahi Chemical Ind Verfahren zur Herstellung von 3-Alkoxymethylcephalosporinen.
JPS63115887A (ja) * 1986-11-04 1988-05-20 Asahi Chem Ind Co Ltd ７−アミノ−３−アルコキシメチルセフアロスポリン類の製造方法
JP2612493B2 (ja) * 1988-05-24 1997-05-21 旭化成工業株式会社 ３―置換メチル―３―セフェム―４―カルボン酸類の製造方法
DE4004370A1 (de) * 1990-02-13 1991-08-14 Hoechst Ag Verfahren zur herstellung von 7-amino-3-methoxymethyl-ceph-3-em-4-carbonsaeure

Also Published As

Publication number Publication date
DK0485204T3 (da) 1995-10-16
EP0485204B1 (de) 1995-05-31
JPH04364188A (ja) 1992-12-16
JP3206821B2 (ja) 2001-09-10
ATE123286T1 (de) 1995-06-15
IE68511B1 (en) 1996-06-26
KR0140196B1 (ko) 1998-06-01
US5451675A (en) 1995-09-19
IE913872A1 (en) 1992-05-20
EP0485204A3 (en) 1992-09-23
ES2075365T3 (es) 1995-10-01
EP0485204A2 (de) 1992-05-13
HK1005452A1 (en) 1999-01-08
DE69110107T2 (de) 1996-02-01
KR920009833A (ko) 1992-06-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee