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DE69005849D1 - Inhalator zur einmaligen Verwendung mit vorperforierter Kapsel. - Google Patents

Inhalator zur einmaligen Verwendung mit vorperforierter Kapsel.

Info

Publication number
DE69005849D1
DE69005849D1 DE90102554T DE69005849T DE69005849D1 DE 69005849 D1 DE69005849 D1 DE 69005849D1 DE 90102554 T DE90102554 T DE 90102554T DE 69005849 T DE69005849 T DE 69005849T DE 69005849 D1 DE69005849 D1 DE 69005849D1
Authority
DE
Germany
Prior art keywords
inhaler
capsule
finely divided
perforated capsule
use inhaler
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90102554T
Other languages
English (en)
Other versions
DE69005849T2 (de
Inventor
Luigi Valentini
Giancarlo Ceschel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phidea SpA
Original Assignee
Phidea SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Phidea SpA filed Critical Phidea SpA
Publication of DE69005849D1 publication Critical patent/DE69005849D1/de
Application granted granted Critical
Publication of DE69005849T2 publication Critical patent/DE69005849T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Cosmetics (AREA)
DE69005849T 1989-02-23 1990-02-09 Inhalator zur einmaligen Verwendung mit vorperforierter Kapsel. Expired - Fee Related DE69005849T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8919540A IT1228460B (it) 1989-02-23 1989-02-23 Inalatore monouso con capsula pre-forata

Publications (2)

Publication Number Publication Date
DE69005849D1 true DE69005849D1 (de) 1994-02-24
DE69005849T2 DE69005849T2 (de) 1994-05-19

Family

ID=11158892

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69005849T Expired - Fee Related DE69005849T2 (de) 1989-02-23 1990-02-09 Inhalator zur einmaligen Verwendung mit vorperforierter Kapsel.

Country Status (6)

Country Link
US (1) US5152284A (de)
EP (1) EP0385156B1 (de)
AT (1) ATE99967T1 (de)
DE (1) DE69005849T2 (de)
ES (1) ES2048874T3 (de)
IT (1) IT1228460B (de)

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DE19835346A1 (de) * 1998-08-05 2000-02-10 Boehringer Ingelheim Pharma Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US7305986B1 (en) * 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
NL1013387C2 (nl) * 1999-10-25 2001-04-26 Marc Spits Inrichting voor het toedienen van medicament.
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US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
EP1381417A4 (de) 2001-04-26 2009-12-30 New England Pharm Inc Vorrichtung zur freisetzung abgemessener dosen flüssiger und pulverförmiger mittel
PL369425A1 (en) * 2001-06-11 2005-04-18 Warner-Lambert Company Llc Breath protection microcapsules
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US20040206350A1 (en) * 2002-12-19 2004-10-21 Nektar Therapeutics Aerosolization apparatus with non-circular aerosolization chamber
US20050056280A1 (en) * 2002-12-31 2005-03-17 Nektar Therapeutics Receptacle for an aerosolizable pharmaceutical formulation
US7669596B2 (en) * 2002-12-31 2010-03-02 Novartis Pharma Ag Aerosolization apparatus with rotating capsule
US7878193B2 (en) * 2003-01-14 2011-02-01 Boehringer Ingelheim International Gmbh Capsule for taking an active substance which can be inhaled
WO2004082557A2 (en) 2003-03-15 2004-09-30 Brin Tech International Limited Package for and formulation of medicaments
PL1610850T3 (pl) * 2003-04-09 2012-11-30 Novartis Ag Urządzenie rozpylające z osłoną wlotu powietrza
US8869794B1 (en) * 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
HUE026950T2 (en) * 2003-04-09 2016-08-29 Novartis Ag Nozzle with guide wire for puncturing the capsule
EP1488819A1 (de) 2003-06-16 2004-12-22 Rijksuniversiteit te Groningen Trockenpulverinhalator und Verfahren zur pulmonalen Inhalation von Trockenpulver
CN100589849C (zh) * 2004-02-24 2010-02-17 微计量技术有限公司 基于合成射流的药物输送方法和装置
CN1946453A (zh) * 2004-04-23 2007-04-11 米斯提克医药有限公司 多倍剂量药品配给系统
EP1786784B1 (de) 2004-08-20 2010-10-27 MannKind Corporation Katalyse der diketopiperazinsynthese
MX2007002189A (es) 2004-08-23 2008-01-11 Mannkind Corp Sales de dicetopiperazina, sales de dicetomorfolina o sales de dicetodioxano para suministro de farmacos.
DE102005001332A1 (de) * 2005-01-11 2006-07-20 Boehringer Ingelheim Pharma Gmbh & Co. Kg Zweiteilige Kapsel mit Vorverschluss zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren
DE102005038619A1 (de) * 2005-08-16 2007-02-22 Pari GmbH Spezialisten für effektive Inhalation Inhalationstherapievorrichtung mit einer Ampulle für die Bevorratung eines zu vernebelnden Medikaments
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BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
US20100154794A1 (en) * 2006-03-21 2010-06-24 Valentin Boris N Inhaler Flow Channel
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WO2008091355A2 (en) * 2007-01-24 2008-07-31 Breathe Pharmaceuticals, Inc. Drug transfer device
US8196576B2 (en) * 2007-02-28 2012-06-12 Microdose Therapeutx, Inc. Inhaler
JP5352583B2 (ja) 2007-05-16 2013-11-27 ミスティック ファーマシューティカルズ, インコーポレイテッド 単位用量投薬用の連結容器
US8683995B2 (en) 2007-05-16 2014-04-01 Mystic Pharmaceuticals, Inc. Dose dispensing containers
US9248076B2 (en) 2007-05-16 2016-02-02 Mystic Pharmaceuticals, Inc. Dose dispensing containers
WO2008156586A2 (en) * 2007-06-12 2008-12-24 Alkermes, Inc. Inhalation device for powdered substances
JP2010538925A (ja) * 2007-09-14 2010-12-16 ミスティック ファーマシューティカルズ, インコーポレイテッド 深絞り容器成形方法
US8015969B2 (en) 2007-09-18 2011-09-13 Robert Abrams Semi-automatic emergency medication dose nebulizer
US8291902B2 (en) 2007-09-18 2012-10-23 Robert Abrams Enhanced semi-automatic emergency medication dose nebulizer
US7814902B2 (en) 2007-09-18 2010-10-19 Robert Abrams Semi-automatic emergency medication dose nebulizer
US7836885B2 (en) 2007-09-18 2010-11-23 Robert Abrams Semi-automatic emergency medication dose nebulizer
US20090151716A1 (en) * 2007-09-18 2009-06-18 Robert Abrams Semi-automatic emergency medication dose nebulizer
US20090071470A1 (en) * 2007-09-18 2009-03-19 Robert Abrams Emergency medication dose nebulizer
DE102007056462B4 (de) 2007-11-23 2011-10-27 Pari Pharma Gmbh Einwegampulle für eine Vorrichtung zur Erzeugung von Aerosolen
PL2254629T3 (pl) * 2008-03-27 2016-06-30 Mannkind Corp Układ inhalatora suchego proszku
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
KR101629154B1 (ko) 2008-06-13 2016-06-21 맨카인드 코포레이션 건조 분말 흡입기 및 약물 투여 시스템
CA2728523C (en) 2008-06-20 2020-03-10 Mannkind Corporation An interactive apparatus and method for real-time profiling of inhalation efforts
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010135672A1 (en) * 2009-05-21 2010-11-25 Microdose Therapeutx, Inc. Rotary cassette system for dry powder inhaler
US8985101B2 (en) 2009-05-21 2015-03-24 Microdose Therapeutx, Inc. Method and device for clamping a blister within a dry powder inhaler
JP5859433B2 (ja) 2009-06-12 2016-02-10 マンカインド コーポレイション 規定された比表面積を有するジケトピペラジン微粒子
US9180263B2 (en) * 2009-07-01 2015-11-10 Microdose Therapeutx, Inc. Laboratory animal pulmonary dosing device
US20110000481A1 (en) * 2009-07-01 2011-01-06 Anand Gumaste Nebulizer for infants and respiratory compromised patients
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
CN104338219B (zh) 2010-01-05 2017-10-24 微剂量治疗技术公司 吸入设备和方法
JP6385673B2 (ja) 2010-06-21 2018-09-05 マンカインド コーポレイション 乾燥粉末薬物送達システム
US8925726B2 (en) 2011-04-01 2015-01-06 Mannkind Corporation Blister package for pharmaceutical cartridges
JP6037315B2 (ja) 2011-05-27 2016-12-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 吸入器及び吸入器用カプセル
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
ES2624294T3 (es) 2012-07-12 2017-07-13 Mannkind Corporation Sistemas de suministro de fármacos en polvo seco
US10159644B2 (en) 2012-10-26 2018-12-25 Mannkind Corporation Inhalable vaccine compositions and methods
US20140150787A1 (en) * 2012-12-04 2014-06-05 Civitas Therapeutics, Inc. Devices and methods for puncturing a capsule to release a powdered medicament therefrom
CN108578372B (zh) 2013-03-15 2021-07-06 曼金德公司 微晶二酮哌嗪组合物以及方法
MX2020009878A (es) 2013-07-18 2022-07-27 Mannkind Corp Composiciones farmaceuticas en polvo seco estables al calor y metodos.
EP3030294B1 (de) 2013-08-05 2020-10-07 MannKind Corporation Insufflationsvorrichtung
US9272123B2 (en) * 2013-12-16 2016-03-01 Esther Gallant Device and method for inserting lubricating capsule
US10238820B2 (en) 2014-01-08 2019-03-26 Seroton, Inc. Dry-powder inhalation device
US11491288B2 (en) 2014-01-08 2022-11-08 Seroton, Inc. Dispenser for dry-powder inhalation devices
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
CN105311717B (zh) * 2014-08-01 2019-04-05 心诚镁行动医电股份有限公司 可携式超音波雾化器及其置药结构
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
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US11864587B2 (en) * 2018-06-15 2024-01-09 Valley Product Concepts, LLC Capsules for use in personal vaporizers

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US2517482A (en) * 1949-04-09 1950-08-01 Sharp & Dohme Inc Inhaler
US3669113A (en) * 1966-03-07 1972-06-13 Fisons Ltd Inhalation device
US3507277A (en) * 1966-09-17 1970-04-21 Fisons Pharmaceuticals Ltd Inhalation device
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DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator

Also Published As

Publication number Publication date
IT1228460B (it) 1991-06-19
IT8919540A0 (it) 1989-02-23
US5152284A (en) 1992-10-06
ATE99967T1 (de) 1994-01-15
ES2048874T3 (es) 1994-04-01
EP0385156B1 (de) 1994-01-12
DE69005849T2 (de) 1994-05-19
EP0385156A1 (de) 1990-09-05

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Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DER INHABER IST ZU AENDERN IN: PH&T S.R.L., MAILAND/MILANO, IT

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee