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DE69919143D1 - Nukleinsäure hybridisierung-testverfahren in lösung - Google Patents

Nukleinsäure hybridisierung-testverfahren in lösung

Info

Publication number
DE69919143D1
DE69919143D1 DE69919143T DE69919143T DE69919143D1 DE 69919143 D1 DE69919143 D1 DE 69919143D1 DE 69919143 T DE69919143 T DE 69919143T DE 69919143 T DE69919143 T DE 69919143T DE 69919143 D1 DE69919143 D1 DE 69919143D1
Authority
DE
Germany
Prior art keywords
nucleic acid
solution
test method
acid hybridization
hybridization test
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69919143T
Other languages
English (en)
Other versions
DE69919143T2 (de
Inventor
Andreas Abel
Joseph Beck
Markus Ehrat
Peter Oroszlan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharma GmbH
Novartis AG
Original Assignee
Novartis Erfindungen Verwaltungs GmbH
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Erfindungen Verwaltungs GmbH, Novartis AG filed Critical Novartis Erfindungen Verwaltungs GmbH
Publication of DE69919143D1 publication Critical patent/DE69919143D1/de
Application granted granted Critical
Publication of DE69919143T2 publication Critical patent/DE69919143T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/682Signal amplification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • C12Q1/6825Nucleic acid detection involving sensors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69919143T 1998-03-19 1999-03-17 Nukleinsäure hybridisierung-testverfahren in lösung Expired - Lifetime DE69919143T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9805935.5A GB9805935D0 (en) 1998-03-19 1998-03-19 Organic compounds
GB9805935 1998-03-19
PCT/EP1999/001782 WO1999047705A1 (en) 1998-03-19 1999-03-17 Detection method

Publications (2)

Publication Number Publication Date
DE69919143D1 true DE69919143D1 (de) 2004-09-09
DE69919143T2 DE69919143T2 (de) 2005-08-11

Family

ID=10828909

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69919143T Expired - Lifetime DE69919143T2 (de) 1998-03-19 1999-03-17 Nukleinsäure hybridisierung-testverfahren in lösung

Country Status (8)

Country Link
US (1) US20060188873A1 (de)
EP (1) EP1064406B1 (de)
JP (1) JP2002506984A (de)
AT (1) ATE272721T1 (de)
AU (1) AU3414599A (de)
DE (1) DE69919143T2 (de)
GB (1) GB9805935D0 (de)
WO (1) WO1999047705A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001262178A1 (en) * 2000-04-14 2001-10-30 Zeptosens Ag Grid-waveguide structure for reinforcing an excitation field and use thereof
EP1281063A1 (de) * 2000-05-06 2003-02-05 Zeptosens AG Gitter-wellenleiter-struktur für multianalytbestimmungen und deren verwendung
WO2002001194A1 (en) 2000-06-25 2002-01-03 Affymetrix, Inc. Optically active substrates
GB0106949D0 (en) * 2001-03-20 2001-05-09 Norchip As Detection of mycobacteria
CA2473558A1 (en) * 2002-01-18 2003-07-31 University Of Utah Research Foundation Detection of single nucleotide polymorphisms using planar waveguides
GB0507835D0 (en) * 2005-04-18 2005-05-25 Solexa Ltd Method and device for nucleic acid sequencing using a planar wave guide
EP1939622B1 (de) * 2005-09-27 2011-09-21 Eisai R&D Management Co., Ltd. Verfahren zur bildung von autoaggregat auf einem mikropartikel und verfahren zum nachweis von zielanalyten
KR20100025328A (ko) * 2008-08-27 2010-03-09 삼성전자주식회사 이중가닥 영역과 말단 단일가닥 영역을 포함하는 이중가닥 핵산 프로브가 고정된 마이크로어레이를 제조하는 방법
US8300993B2 (en) 2009-03-02 2012-10-30 Mbio Diagnostics, Inc. Waveguide with integrated lens
US8331751B2 (en) 2009-03-02 2012-12-11 mBio Diagnositcs, Inc. Planar optical waveguide with core of low-index-of-refraction interrogation medium
US9212995B2 (en) 2009-03-02 2015-12-15 Mbio Diagnostics, Inc. System and method for detecting multiple molecules in one assay
US9658222B2 (en) 2009-03-02 2017-05-23 Mbio Diagnostics, Inc. Planar waveguide based cartridges and associated methods for detecting target analyte
US9109793B2 (en) * 2009-07-20 2015-08-18 Crayola, Llc Illuminated display unit
EP2616797B1 (de) 2010-09-15 2017-01-11 MBIO Diagnostics Inc. System und verfahren zur detektion von mehreren molekülen in einem assay
CN104136611B (zh) 2012-02-27 2018-03-27 东丽株式会社 核酸的检测方法
WO2020146552A1 (en) * 2019-01-08 2020-07-16 Akoya Biosciences, Inc. Flexible detection systems

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US5283174A (en) * 1987-09-21 1994-02-01 Gen-Probe, Incorporated Homogenous protection assay
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
GB9119735D0 (en) * 1991-09-16 1991-10-30 Secr Defence Gene probe biosensor method
US5681697A (en) * 1993-12-08 1997-10-28 Chiron Corporation Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor
DE69637315T2 (de) * 1995-05-12 2008-08-28 Novartis Ag Verfahren zur parallelen bestimmung mehrerer analyten mittels evaneszent angeregter lumineszenz
AU4040097A (en) * 1996-07-12 1998-02-09 Tm Technologies, Inc. Signal amplification method
US5832165A (en) * 1996-08-28 1998-11-03 University Of Utah Research Foundation Composite waveguide for solid phase binding assays

Also Published As

Publication number Publication date
EP1064406B1 (de) 2004-08-04
JP2002506984A (ja) 2002-03-05
ATE272721T1 (de) 2004-08-15
GB9805935D0 (en) 1998-05-13
EP1064406A1 (de) 2001-01-03
DE69919143T2 (de) 2005-08-11
AU3414599A (en) 1999-10-11
US20060188873A1 (en) 2006-08-24
WO1999047705A1 (en) 1999-09-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC

8328 Change in the person/name/address of the agent

Representative=s name: LUETJENS, H., DIPL.-CHEM. DR. RER. NAT., PAT.-ANW.