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DE69908614D1 - Herstellung von n-substituierten-hydroxycycloalkylamin-derivaten - Google Patents

Herstellung von n-substituierten-hydroxycycloalkylamin-derivaten

Info

Publication number
DE69908614D1
DE69908614D1 DE69908614T DE69908614T DE69908614D1 DE 69908614 D1 DE69908614 D1 DE 69908614D1 DE 69908614 T DE69908614 T DE 69908614T DE 69908614 T DE69908614 T DE 69908614T DE 69908614 D1 DE69908614 D1 DE 69908614D1
Authority
DE
Germany
Prior art keywords
substituted
production
hydroxycycloalkylamine
derivatives
hydroxycycloalkylamine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69908614T
Other languages
English (en)
Other versions
DE69908614T2 (de
Inventor
Jin Kim
Il Kim
Youl Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lotte Fine Chemical Co Ltd
Original Assignee
Samsung Fine Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samsung Fine Chemicals Co Ltd filed Critical Samsung Fine Chemicals Co Ltd
Application granted granted Critical
Publication of DE69908614D1 publication Critical patent/DE69908614D1/de
Publication of DE69908614T2 publication Critical patent/DE69908614T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/06—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/42—Oxygen atoms attached in position 3 or 5
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69908614T 1998-09-17 1999-09-15 Herstellung von n-substituierten-hydroxycycloalkylamin-derivaten Expired - Fee Related DE69908614T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR9838476 1998-09-17
KR1019980038476A KR100295740B1 (ko) 1998-09-17 1998-09-17 N-치환된-하이드록시고리화알킬아민유도체의제조방법
PCT/KR1999/000553 WO2000015610A1 (en) 1998-09-17 1999-09-15 The preparation of n-substituted-hydroxycycloalkylamine derivatives

Publications (2)

Publication Number Publication Date
DE69908614D1 true DE69908614D1 (de) 2003-07-10
DE69908614T2 DE69908614T2 (de) 2004-04-29

Family

ID=19550950

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69908614T Expired - Fee Related DE69908614T2 (de) 1998-09-17 1999-09-15 Herstellung von n-substituierten-hydroxycycloalkylamin-derivaten

Country Status (10)

Country Link
US (1) US6566525B1 (de)
EP (1) EP1114027B1 (de)
JP (1) JP2002524550A (de)
KR (1) KR100295740B1 (de)
CN (1) CN1137095C (de)
AU (1) AU5762099A (de)
CA (1) CA2343837A1 (de)
DE (1) DE69908614T2 (de)
ES (1) ES2200550T3 (de)
WO (1) WO2000015610A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100428999B1 (ko) * 2000-10-07 2004-04-29 한국과학기술원 일차 아민 또는 치환되지 않은 아미노 화합물의 제조방법
ATE450513T1 (de) * 2004-11-04 2009-12-15 Mallinckrodt Inc Opiatzwischenprodukte und syntheseverfahren
KR100939347B1 (ko) 2005-07-20 2010-01-29 (주)카이로드 광학적으로 순수한 (ｓ)-3-히드록시 피롤리딘의 제조방법
US7622586B2 (en) * 2005-10-21 2009-11-24 Mallinckrodt Inc. Opiate intermediates and methods of synthesis
US7511060B2 (en) 2005-10-21 2009-03-31 Mallinckrodt Inc. Opiate intermediates and methods of synthesis
CN101070301B (zh) * 2006-05-08 2011-06-08 中国科学院化学研究所 一种双羟基高脯氨酸衍生物及其制备方法与应用
DK2094079T3 (da) * 2006-11-24 2013-01-02 Novartis Ag Sammensætning til fordrivelse og afskrækkelse af utøj
US9458354B2 (en) 2010-10-06 2016-10-04 Resinate Technologies, Inc. Polyurethane dispersions and methods of making and using same
KR101507696B1 (ko) 2011-06-10 2015-04-07 크리스토퍼 엠. 펠리체 투명 코팅, 아크릴 코팅
CN102603705A (zh) * 2012-03-27 2012-07-25 武汉大学 取代基中α-碳上带活性官能团的手性五元环亚硫酸酯的制备方法
TWI532232B (zh) * 2013-12-18 2016-05-01 國立臺灣科技大學 鋰電池以及鋰電池用的電解液添加劑
EP4382529A1 (de) 2022-12-07 2024-06-12 Bayer Consumer Care AG Verfahren zur herstellung von reinem (3s)-pyrrolidin-3-ol und reinem (3s)-pyrrolidin-3-ol-hydrochlorid

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5817183B2 (ja) * 1980-12-03 1983-04-05 広栄化学工業株式会社 ４−アミノ−１，２−ブタンジオ−ル及びその製造法
US4705853A (en) 1982-09-30 1987-11-10 A. H. Robins Company, Inc. Fused aromatic oxazepinones, thiazepinones, diazepinones and sulfur analogs thereof
US5364872A (en) 1984-04-16 1994-11-15 Yamanouchi Pharmaceutical Co., Ltd. Dihydropyridine-3,5-dicarboxylic acid ester derivatives
JPH01254658A (ja) * 1988-04-04 1989-10-11 Kanegafuchi Chem Ind Co Ltd 新規ピロリジノン及びその製造法
GB8824400D0 (en) 1988-10-18 1988-11-23 Glaxo Group Ltd Chemical compounds
US4937235A (en) 1989-01-23 1990-06-26 American Cyanamid Company 3- or 4-substituted oxotremorine derivatives
US5233053A (en) 1989-03-17 1993-08-03 Pfizer Inc. Pyrrolidine derivatives
US4916141A (en) 1989-03-28 1990-04-10 Warner-Lambert Company (S)-7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
JPH03153660A (ja) * 1989-11-10 1991-07-01 Kanegafuchi Chem Ind Co Ltd ４―ハロ―３―ヒドロキシブタンニトリルのスルホン酸エステルおよびその製造法
JP2735326B2 (ja) * 1989-12-02 1998-04-02 鐘淵化学工業株式会社 ３‐ピロリジノールの製造法
JPH03200762A (ja) * 1989-12-27 1991-09-02 Kanegafuchi Chem Ind Co Ltd １―ベルジル―３―ピロリジノールの製造方法
JPH0776209B2 (ja) * 1990-04-11 1995-08-16 高砂香料工業株式会社 光学活性３―ヒドロキシピロリジン誘導体の製造方法
JPH04164066A (ja) * 1990-10-29 1992-06-09 Denki Kagaku Kogyo Kk （ｒｓ）―３―ピロリジノールの光学分割法
CA2058640A1 (en) 1991-01-25 1992-07-26 Richard R. Scherschlicht Tricyclic pyridone derivative
JPH05227991A (ja) * 1992-02-19 1993-09-07 Kyowa Hakko Kogyo Co Ltd 光学活性な３−ピロリジノール誘導体の製造法
JP3251722B2 (ja) * 1993-06-14 2002-01-28 広栄化学工業株式会社 Ｎ−置換−３−ピペリジノールの製法
US5347017A (en) * 1993-07-07 1994-09-13 Warner-Lambert Company Process for chiral 3-(1-amino-1,1-bisalkylmethyl)-1-substituted-pyrrolidines
BE1007297A3 (nl) * 1993-07-19 1995-05-09 Dsm Nv Werkwijze voor de bereiding van optisch aktieve alcoholen en esters, en alcoholen en esters toegepast en bereid in dergelijke werkwijzen.
IL117440A0 (en) * 1995-03-31 1996-07-23 Pfizer Pyrrolidinyl hydroxamic acid compounds and their production process
JPH10150998A (ja) * 1996-11-26 1998-06-09 Kanegafuchi Chem Ind Co Ltd Ｎ−ベンジル−３−ピロリジノールの製造方法
US5977381A (en) * 1998-01-12 1999-11-02 Hoffmann-La Roche Inc. Process for making 3-amino-pyrolidine derivatives

Also Published As

Publication number Publication date
AU5762099A (en) 2000-04-03
DE69908614T2 (de) 2004-04-29
EP1114027B1 (de) 2003-06-04
CN1137095C (zh) 2004-02-04
CN1323293A (zh) 2001-11-21
US6566525B1 (en) 2003-05-20
KR100295740B1 (ko) 2001-11-05
ES2200550T3 (es) 2004-03-01
WO2000015610A1 (en) 2000-03-23
EP1114027A1 (de) 2001-07-11
CA2343837A1 (en) 2000-03-23
JP2002524550A (ja) 2002-08-06
KR20000020053A (ko) 2000-04-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: SAMSUNG FINE CHEMICALS CO., LTD., UKSAN, KR

8327 Change in the person/name/address of the patent owner

Owner name: SAMSUNG FINE CHEMICALS CO., LTD., ULSAN, KR

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee