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DE69840263D1 - GEN INTRODUCTION IN MARK MOTONEURONS BY MEANS OF A NAKED DNA - Google Patents

GEN INTRODUCTION IN MARK MOTONEURONS BY MEANS OF A NAKED DNA

Info

Publication number
DE69840263D1
DE69840263D1 DE69840263T DE69840263T DE69840263D1 DE 69840263 D1 DE69840263 D1 DE 69840263D1 DE 69840263 T DE69840263 T DE 69840263T DE 69840263 T DE69840263 T DE 69840263T DE 69840263 D1 DE69840263 D1 DE 69840263D1
Authority
DE
Germany
Prior art keywords
motoneurons
gen
mark
introduction
naked dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69840263T
Other languages
German (de)
Inventor
Francoise Finiels
Minerva Gimenez-Ribotta
Jacques Mallet
Alain Privat
Frederic Revah
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut National de la Sante et de la Recherche Medicale INSERM
Aventis Pharma SA
Original Assignee
Institut National de la Sante et de la Recherche Medicale INSERM
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/785,074 external-priority patent/US6632427B1/en
Application filed by Institut National de la Sante et de la Recherche Medicale INSERM, Aventis Pharma SA filed Critical Institut National de la Sante et de la Recherche Medicale INSERM
Priority claimed from PCT/EP1998/000220 external-priority patent/WO1998031395A1/en
Application granted granted Critical
Publication of DE69840263D1 publication Critical patent/DE69840263D1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)

Abstract

Nucleic acid (I) is delivered to motor neurons by administering it to muscle from which it is transported to, and expresses protein (II) in, the neurons.
DE69840263T 1997-01-17 1998-01-16 GEN INTRODUCTION IN MARK MOTONEURONS BY MEANS OF A NAKED DNA Expired - Lifetime DE69840263D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/785,074 US6632427B1 (en) 1994-12-13 1997-01-17 Adenoviral-vector-mediated gene transfer into medullary motor neurons
US4224797P 1997-03-31 1997-03-31
PCT/EP1998/000220 WO1998031395A1 (en) 1997-01-17 1998-01-16 Adenoviral-vector-mediated gene transfer into medullary motor neurons

Publications (1)

Publication Number Publication Date
DE69840263D1 true DE69840263D1 (en) 2009-01-08

Family

ID=21920853

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69840263T Expired - Lifetime DE69840263D1 (en) 1997-01-17 1998-01-16 GEN INTRODUCTION IN MARK MOTONEURONS BY MEANS OF A NAKED DNA

Country Status (4)

Country Link
KR (1) KR20000070272A (en)
AT (1) ATE415174T1 (en)
DE (1) DE69840263D1 (en)
HU (1) HUP0000923A3 (en)

Also Published As

Publication number Publication date
HUP0000923A3 (en) 2002-01-28
HUP0000923A1 (en) 2000-07-28
ATE415174T1 (en) 2008-12-15
KR20000070272A (en) 2000-11-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition