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DE69821530D1 - Dihydrobenzifurane - Google Patents

Dihydrobenzifurane

Info

Publication number
DE69821530D1
DE69821530D1 DE69821530T DE69821530T DE69821530D1 DE 69821530 D1 DE69821530 D1 DE 69821530D1 DE 69821530 T DE69821530 T DE 69821530T DE 69821530 T DE69821530 T DE 69821530T DE 69821530 D1 DE69821530 D1 DE 69821530D1
Authority
DE
Germany
Prior art keywords
dihydrobenzifurane
meaningand
heterocycle
meanings
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69821530T
Other languages
English (en)
Other versions
DE69821530T2 (de
Inventor
Ulrich Thibaut
Armin Hatzelmann
Hildegard Boss
Dietrich Haefner
Rolf Beume
Hans-Peter Kley
Hendrik Timmerman
Der Laan Johanna Van
Wolf-Ruediger Ulrich
Jan Sterk
Der Mey Margaretha Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Application granted granted Critical
Publication of DE69821530D1 publication Critical patent/DE69821530D1/de
Publication of DE69821530T2 publication Critical patent/DE69821530T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69821530T 1997-12-15 1998-12-10 Dihydrobenzifurane Expired - Fee Related DE69821530T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97122039 1997-12-15
EP97122039 1997-12-15
PCT/EP1998/008054 WO1999031090A1 (en) 1997-12-15 1998-12-10 Dihydrobenzofurans

Publications (2)

Publication Number Publication Date
DE69821530D1 true DE69821530D1 (de) 2004-03-11
DE69821530T2 DE69821530T2 (de) 2004-12-23

Family

ID=8227798

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69821530T Expired - Fee Related DE69821530T2 (de) 1997-12-15 1998-12-10 Dihydrobenzifurane

Country Status (17)

Country Link
US (1) US6380196B1 (de)
EP (1) EP1042319B1 (de)
JP (1) JP2002508368A (de)
AT (1) ATE258930T1 (de)
AU (1) AU753576B2 (de)
CA (1) CA2314111A1 (de)
CZ (1) CZ299304B6 (de)
DE (1) DE69821530T2 (de)
DK (1) DK1042319T3 (de)
EE (1) EE04312B1 (de)
ES (1) ES2216349T3 (de)
HU (1) HU225114B1 (de)
IL (1) IL136359A (de)
PL (1) PL191236B1 (de)
PT (1) PT1042319E (de)
SI (1) SI1042319T1 (de)
WO (1) WO1999031090A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1202865C (zh) 1999-08-21 2005-05-25 奥坦纳医药公司 增效组合物
WO2001019818A1 (en) * 1999-09-14 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Phthalazinone derivatives as pd3/4 inhibitors
AU781503B2 (en) * 1999-10-25 2005-05-26 Altana Pharma Ag Phthalazinone derivatives as PDE 4 inhibitors
EP1244654A1 (de) 1999-10-25 2002-10-02 ALTANA Pharma AG Tetrahydrothiopyranphthalazinon-derivate als pde 4 hemmer
HUP0301240A3 (en) * 2000-06-05 2004-03-29 Altana Pharma B V Pyridazine compounds effective as beta-2-adrenoreceptor agonists as well as pde4-inhibitors and pharmaceutical compositions containing them
CZ20032491A3 (cs) 2001-02-15 2004-01-14 Altana Pharma Ag Ftalazinonpiperidinové deriváty
EP1385838A1 (de) * 2001-04-25 2004-02-04 ALTANA Pharma AG Piperazinoderivate und deren verwendung als pde4-inhibitoren
JP2004526789A (ja) 2001-04-25 2004-09-02 アルタナ　ファルマ　アクチエンゲゼルシャフト 新規フタラジノン
CA2480054A1 (en) * 2002-03-29 2003-10-09 Chugai Seiyaku Kabushiki Kaisha Pharmaceutical composition for preventing or treating respiratory disease
PL372926A1 (en) * 2002-08-10 2005-08-08 Altana Pharma Ag Piperidine-pyridazones and phthalazones as pde4 inhibitors
WO2004018449A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Piperidine-derivatives as pde4 inhibitors
CA2494650A1 (en) * 2002-08-10 2004-03-04 Altana Pharma Ag Pyridazinone-derivatives as pde4 inhibitors
AU2003260371A1 (en) * 2002-08-10 2004-03-11 Altana Pharma Ag Piperidine-n-oxide-derivatives
US20080227790A1 (en) * 2004-02-04 2008-09-18 Altana Pharma Ag Pyridazinone Derivatives and their Use as Pde4 Inhibitors
EP1716133B1 (de) * 2004-02-04 2008-03-26 Nycomed GmbH 2-(piperidin-4-yl)-4,5-dihydro-2h-pyridazin-3-on-derivate als pde4-inhibitoren
JP4890439B2 (ja) * 2005-03-07 2012-03-07 杏林製薬株式会社 ピラゾロピリジン−４−イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするｐｄｅ阻害剤
AR057986A1 (es) * 2005-11-21 2008-01-09 Japan Tobacco Inc Compuesto heterociclico y su uso farmaceutico
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4721784A (en) * 1986-12-22 1988-01-26 Ortho Pharmaceutical Corporation 6-benzoxazinyl-2,3,4,5-tetrahydropyridazin-3-ones
AU640137B2 (en) * 1989-04-17 1993-08-19 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel arylpyridazines, their manufacture, use and medicaments containing them
JP3120857B2 (ja) 1990-02-19 2000-12-25 中外製薬株式会社 新規な縮合複素環化合物とこれを用いた抗喘息剤
AU8722991A (en) * 1990-10-16 1992-05-20 Byk Gulden Lomberg Chemische Fabrik Gmbh Arylpyridazinones
US5449676A (en) * 1991-04-26 1995-09-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyridazines
AU2229992A (en) * 1991-07-05 1993-02-11 Byk Gulden Lomberg Chemische Fabrik Gmbh Use of substituted pyridazines against dermatosis
WO1993007146A1 (en) 1991-10-09 1993-04-15 Syntex (U.S.A.) Inc. Benzo and pyrido pyridazinone and pyridazinthione compounds with pde iv inhibiting activity
DE4230755A1 (de) * 1992-09-14 1994-03-17 Schering Ag Verwendung von PDE-Inhibitoren bei der Behandlung von Nieren- und Ureter-Erkrankungen
WO1994012461A1 (en) 1992-12-02 1994-06-09 Pfizer Inc. Catechol diethers as selective pdeiv inhibitors
US5476834A (en) * 1993-03-17 1995-12-19 Sumitomo Chemical Company, Limited Dihydrobenzofuran derivatives, their production and use
AU702346B2 (en) * 1994-07-22 1999-02-18 Altana Pharma Ag Dihydrobenzofuranes
HU219864B (hu) 1994-08-09 2001-08-28 Eisai Co., Ltd. cGMP-PDE inhibitor kondenzált piridazinszármazékok és alkalmazásuk
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
US5821250A (en) * 1996-02-01 1998-10-13 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents

Also Published As

Publication number Publication date
AU753576B2 (en) 2002-10-24
PL191236B1 (pl) 2006-04-28
EP1042319B1 (de) 2004-02-04
EE04312B1 (et) 2004-06-15
ATE258930T1 (de) 2004-02-15
HUP0004561A3 (en) 2002-04-29
EP1042319A1 (de) 2000-10-11
PT1042319E (pt) 2004-06-30
JP2002508368A (ja) 2002-03-19
CZ299304B6 (cs) 2008-06-11
PL341239A1 (en) 2001-03-26
HUP0004561A2 (hu) 2002-03-28
SI1042319T1 (en) 2004-08-31
AU2270199A (en) 1999-07-05
DE69821530T2 (de) 2004-12-23
WO1999031090A1 (en) 1999-06-24
US6380196B1 (en) 2002-04-30
DK1042319T3 (da) 2004-06-01
IL136359A0 (en) 2001-06-14
ES2216349T3 (es) 2004-10-16
IL136359A (en) 2003-03-12
EE200000335A (et) 2001-10-15
HU225114B1 (en) 2006-06-28
CZ20002218A3 (cs) 2000-11-15
CA2314111A1 (en) 1999-06-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NYCOMED GMBH, 78467 KONSTANZ, DE

8339 Ceased/non-payment of the annual fee