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DE69532804D1 - Verwendung von hemmern des maillard-reaktion zur behandlung von krankheiten zufolge amyloidosis - Google Patents

Verwendung von hemmern des maillard-reaktion zur behandlung von krankheiten zufolge amyloidosis

Info

Publication number
DE69532804D1
DE69532804D1 DE69532804T DE69532804T DE69532804D1 DE 69532804 D1 DE69532804 D1 DE 69532804D1 DE 69532804 T DE69532804 T DE 69532804T DE 69532804 T DE69532804 T DE 69532804T DE 69532804 D1 DE69532804 D1 DE 69532804D1
Authority
DE
Germany
Prior art keywords
amyloidosis
maillard reaction
treating diseases
reaction inhibitors
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69532804T
Other languages
English (en)
Other versions
DE69532804T2 (de
Inventor
Camilo Colaco
Bruce Joseph Roser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Quadrant Drug Delivery Ltd
Original Assignee
Elan Drug Delivery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10753465&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69532804(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Elan Drug Delivery Ltd filed Critical Elan Drug Delivery Ltd
Publication of DE69532804D1 publication Critical patent/DE69532804D1/de
Application granted granted Critical
Publication of DE69532804T2 publication Critical patent/DE69532804T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69532804T 1994-04-13 1995-04-13 Verwendung von hemmern der maillard-reaktion zur behandlung von krankheiten zufolge amyloidosis Expired - Fee Related DE69532804T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9407305A GB2288732B (en) 1994-04-13 1994-04-13 Pharmaceutical compositions
GB9407305 1994-04-13
PCT/GB1995/000843 WO1995028151A1 (en) 1994-04-13 1995-04-13 Use of maillard reaction inhibitors for the treatment of amyloidosis-based disease

Publications (2)

Publication Number Publication Date
DE69532804D1 true DE69532804D1 (de) 2004-05-06
DE69532804T2 DE69532804T2 (de) 2005-02-10

Family

ID=10753465

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532804T Expired - Fee Related DE69532804T2 (de) 1994-04-13 1995-04-13 Verwendung von hemmern der maillard-reaktion zur behandlung von krankheiten zufolge amyloidosis

Country Status (11)

Country Link
US (2) US5891873A (de)
EP (1) EP0755249B1 (de)
JP (1) JPH09512005A (de)
AT (1) ATE262895T1 (de)
AU (1) AU2219795A (de)
DE (1) DE69532804T2 (de)
DK (1) DK0755249T3 (de)
ES (1) ES2216012T3 (de)
GB (1) GB2288732B (de)
PT (1) PT755249E (de)
WO (1) WO1995028151A1 (de)

Families Citing this family (30)

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US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6673335B1 (en) * 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
PT679088E (pt) * 1992-09-29 2002-12-31 Inhale Therapeutic Syst Administracao pulmonar de fragmentos activos de hormona paratiroide
US20030113273A1 (en) * 1996-06-17 2003-06-19 Patton John S. Methods and compositions for pulmonary delivery of insulin
CZ295827B6 (cs) * 1994-03-07 2005-11-16 Nektar Therapeutics Způsob aerosolizace dávky inzulinu, inzulinový přípravek a jeho použití
GB2288732B (en) * 1994-04-13 1998-04-29 Quadrant Holdings Cambridge Pharmaceutical compositions
AU696387B2 (en) * 1994-05-18 1998-09-10 Inhale Therapeutic Systems, Inc. Methods and compositions for the dry powder formulation of interferons
US6290991B1 (en) * 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6512010B1 (en) 1996-07-15 2003-01-28 Alza Corporation Formulations for the administration of fluoxetine
US5780513A (en) * 1996-08-22 1998-07-14 Washington University Method of inhibiting the release of bioactive IL-1
US6203817B1 (en) 1997-02-19 2001-03-20 Alza Corporation Reduction of skin reactions caused by transdermal drug delivery
US20030035778A1 (en) * 1997-07-14 2003-02-20 Robert Platz Methods and compositions for the dry powder formulation of interferon
JPH1143432A (ja) * 1997-07-25 1999-02-16 Biremo Sci:Kk 脳の老化抑制及び治療剤
US6565885B1 (en) * 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) * 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
WO1999039716A1 (fr) * 1998-02-03 1999-08-12 Senju Pharmaceutical Co., Ltd. Substances preventives et medicaments destines aux maladies neurodegeneratives
GB9916316D0 (en) 1999-07-12 1999-09-15 Quadrant Holdings Cambridge Dry powder compositions
CA2378953A1 (en) * 1999-07-27 2001-02-01 Abgenix, Inc. Methods and compositions for inhibiting polypeptide accumulation associated with neurological disorders
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
ES2525087T5 (es) 2000-05-10 2018-06-28 Novartis Ag Polvos basados en fosfolípidos para administración de fármacos
WO2002009674A2 (en) * 2000-07-28 2002-02-07 Inhale Therapeutic Systems, Inc. Methods and compositions to upregulate, redirect or limit immune responses to bioactive compounds
WO2003053411A1 (en) 2001-12-19 2003-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
JP5053264B2 (ja) * 2005-05-19 2012-10-17 アムジェン インコーポレイテッド 抗体の安定性を増加させるための組成物および方法
AU2006251832A1 (en) * 2005-05-27 2006-11-30 Queen's University At Kingston Treatment of protein folding disorders
US20070031342A1 (en) * 2005-06-22 2007-02-08 Nektar Therapeutics Sustained release microparticles for pulmonary delivery
EP2081553B1 (de) * 2006-10-06 2020-08-12 Amgen Inc. Stabile antikörper-formulierungen
CL2007002881A1 (es) * 2006-10-20 2008-05-09 Amgen Inc Formulacion estable que comprende un tampon con un ph de aproximadamente 4 y menos de 6, un cation divalente de 5-150 mm, un excipiente que comprende un azucar o un poliol, y un anticuerpo anti-receptor del factor de crecimiento epidermico; y metodo
DK3636751T3 (da) 2017-06-07 2024-01-29 Amano Enzyme Inc Lactase-bulkpulver og lactasepræparat

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0325936A3 (de) * 1988-01-16 1990-01-17 Ono Pharmaceutical Co., Ltd. Aminoguanidin-Derivate und für die Maillardreaktion inhibitorische Substanzen, die sie als aktive Inhaltsstoffe enthalten
JPH03161441A (ja) * 1989-11-20 1991-07-11 Senjiyu Seiyaku Kk メイラード反応阻害剤
JP2854631B2 (ja) * 1989-11-21 1999-02-03 千寿製薬株式会社 糖尿病合併症および老化によって引き起こされる疾患の予防・治療剤
ZA909529B (en) * 1989-11-28 1992-08-26 Syntex Inc New tricyclic compounds
DE69113938T2 (de) * 1990-02-19 1996-04-11 Senju Pharma Co Zusammensetzungen von Maillard-Reaktion inhibitoren.
KR100353486B1 (ko) * 1990-03-02 2003-01-06 스테이트 오브 오레곤,액팅 바이 앤드 쓰로우 디 오레곤 스테이트 보드 오브 하이어 에주케이션,액팅포앤드 온 비해프 오브 디 오레곤 헬쓰 사이언시즈 유니버시티 앤드 더 유니버시티 오브 오레곤,유진,오레곤 삼치환및사치환된구아니딘류및이를함유하는약제조성물
US5112596A (en) * 1990-04-23 1992-05-12 Alkermes, Inc. Method for increasing blood-brain barrier permeability by administering a bradykinin agonist of blood-brain barrier permeability
ATE288262T1 (de) * 1991-02-08 2005-02-15 Scion Pharmaceuticals Inc Substituierte guanidine und derivate hiervon als modulatoren der freisetzung von neurotransmittern und neue methode zur identifizierung von inhibitoren der neurotransmitter-freisetzung
TW221689B (de) * 1991-08-27 1994-03-11 Otsuka Pharma Co Ltd
US5453514A (en) * 1992-12-25 1995-09-26 Yamanouchi Pharmaceutical Co., Ltd. Pyrazole derivatives and compositions and methods of use as maillard reaction inhibitors
CA2182731A1 (en) * 1994-02-03 1995-08-10 Michael P. Vitek Compositions and methods for advanced glycosylation endproduct-mediated modulation of amyloidosis
GB2288732B (en) * 1994-04-13 1998-04-29 Quadrant Holdings Cambridge Pharmaceutical compositions

Also Published As

Publication number Publication date
GB2288732A (en) 1995-11-01
GB9407305D0 (en) 1994-06-08
EP0755249B1 (de) 2004-03-31
US6034080A (en) 2000-03-07
DK0755249T3 (da) 2004-07-26
ES2216012T3 (es) 2004-10-16
JPH09512005A (ja) 1997-12-02
WO1995028151A1 (en) 1995-10-26
AU2219795A (en) 1995-11-10
GB2288732B (en) 1998-04-29
US5891873A (en) 1999-04-06
PT755249E (pt) 2004-08-31
DE69532804T2 (de) 2005-02-10
EP0755249A1 (de) 1997-01-29
ATE262895T1 (de) 2004-04-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee