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DE69434269D1 - Opioid-rezeptoren, verfahren zu deren herstellung und zusammensetzungen die diese rezeptoren enthalten - Google Patents

Opioid-rezeptoren, verfahren zu deren herstellung und zusammensetzungen die diese rezeptoren enthalten

Info

Publication number
DE69434269D1
DE69434269D1 DE69434269T DE69434269T DE69434269D1 DE 69434269 D1 DE69434269 D1 DE 69434269D1 DE 69434269 T DE69434269 T DE 69434269T DE 69434269 T DE69434269 T DE 69434269T DE 69434269 D1 DE69434269 D1 DE 69434269D1
Authority
DE
Germany
Prior art keywords
receptors
compositions
production
opioid
opioid receptors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69434269T
Other languages
English (en)
Other versions
DE69434269T2 (de
Inventor
I Bell
Terry Reisine
Kazuki Yasuda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Arch Development Corp
Original Assignee
Arch Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arch Development Corp filed Critical Arch Development Corp
Publication of DE69434269D1 publication Critical patent/DE69434269D1/de
Application granted granted Critical
Publication of DE69434269T2 publication Critical patent/DE69434269T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/033—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the internal surface of the plasma membrane, e.g. containing a myristoylation motif
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69434269T 1993-05-20 1994-05-20 Opioid-rezeptoren, verfahren zu deren herstellung und zusammensetzungen die diese rezeptoren enthalten Expired - Fee Related DE69434269T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US100694 1987-09-24
US6629693A 1993-05-20 1993-05-20
US66296 1993-05-20
US10069493A 1993-07-30 1993-07-30
US147592 1993-11-05
US08/147,592 US6096513A (en) 1993-05-20 1993-11-05 Polynucleotides encoding KAPPA opiod receptors
PCT/US1994/005747 WO1994028132A2 (en) 1993-05-20 1994-05-20 Opioid receptors: compositions and methods

Publications (2)

Publication Number Publication Date
DE69434269D1 true DE69434269D1 (de) 2005-03-17
DE69434269T2 DE69434269T2 (de) 2006-03-30

Family

ID=27370939

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69434269T Expired - Fee Related DE69434269T2 (de) 1993-05-20 1994-05-20 Opioid-rezeptoren, verfahren zu deren herstellung und zusammensetzungen die diese rezeptoren enthalten

Country Status (7)

Country Link
US (2) US6096513A (de)
EP (1) EP0700438B1 (de)
JP (2) JPH09501307A (de)
AU (1) AU678266B2 (de)
CA (1) CA2163350A1 (de)
DE (1) DE69434269T2 (de)
WO (1) WO1994028132A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6258556B1 (en) * 1993-02-26 2001-07-10 The United States Of America As Represented By The Department Of Health And Human Services cDNA and genomic clones encoding human μ opiate receptor and the purified gene product
US5747279A (en) * 1993-11-05 1998-05-05 Sloan-Kettering Institute For Cancer Research Nucleic acid molecules encoding kappa3 opioid receptors, receptors encoded thereby, and uses thereof
FR2722209B1 (fr) * 1994-07-11 1996-08-14 Univ Pasteur Recepteur opioide kappa humain, acides nucleiques et utilisations
CA2206192A1 (en) 1996-06-13 1997-12-13 F. Hoffmann-La Roche Ag Modulation of lc132 (opioid-like) receptor function
US20030104572A1 (en) * 1997-12-05 2003-06-05 Pasternak Gavril W. Nucleic acid molecules encoding kappa3, opioid receptors, receptors encoded thereby, and uses thereof
US6627734B1 (en) 1998-07-16 2003-09-30 Memorial Sloan-Kettering Cancer Center Identification and characterization of multiple splice variants of the Kappa3-related opioid receptor (KOR-3) gene
US6306576B1 (en) * 1999-02-19 2001-10-23 Cleveland Clinic Foundation Diagnostic methods for asthma
JP3989247B2 (ja) * 1999-12-06 2007-10-10 ユーロ−セルティーク エス．エイ． ノシセプチン受容体親和性を有するトリアゾスピロ化合物
US7033759B2 (en) * 2000-07-14 2006-04-25 The Rockfeller University Variants of the human kappa opioid receptor gene
WO2005015242A1 (en) * 2003-08-06 2005-02-17 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled opioid receptor kappa 1 (opkr1)
CA2544821A1 (en) * 2003-11-06 2005-05-19 Banyu Pharmaceutical Co., Ltd. Simian orl1 gene and method of assessing compound
JP2008514612A (ja) * 2004-09-23 2008-05-08 ミシャロウ、アレクサンダー 対抗適応を誘発することにより神経伝達物質系を調節する方法
US20070110786A1 (en) * 2005-11-15 2007-05-17 Boston Scientific Scimed, Inc. Medical articles having enhanced therapeutic agent binding
WO2010022145A2 (en) * 2008-08-19 2010-02-25 The University Of North Carolina At Chapel Hill Alternatively-spliced isoform of mu-opioid receptor gene with cell excitatory function

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101368A0 (en) * 1991-03-28 1992-11-15 American Cyanamid Co Somatostatin receptor
WO1993019086A1 (en) * 1992-03-23 1993-09-30 American Cyanamid Company Purified opioid receptor
DK0656007T3 (da) * 1992-08-13 2003-10-06 Univ California Delta opioidreceptor-gener
FR2697850B1 (fr) * 1992-11-10 1994-12-02 Univ Pasteur Nouveaux polypeptides ayant une activité de récepteur opioïde, acides nucléiques codant pour ces polypeptides et utilisations.
EP0612845A3 (en) * 1993-02-26 1994-09-21 American Cyanamid Co Purified opioid receptor.

Also Published As

Publication number Publication date
EP0700438A1 (de) 1996-03-13
AU678266B2 (en) 1997-05-22
US6096513A (en) 2000-08-01
DE69434269T2 (de) 2006-03-30
WO1994028132A3 (en) 1995-05-04
EP0700438B1 (de) 2005-02-09
US6319686B1 (en) 2001-11-20
WO1994028132A2 (en) 1994-12-08
JPH09501307A (ja) 1997-02-10
AU7138294A (en) 1994-12-20
CA2163350A1 (en) 1994-12-08
JP2005124574A (ja) 2005-05-19

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee