[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DE69427695D1 - Neues verfahren und geraet - Google Patents

Neues verfahren und geraet

Info

Publication number
DE69427695D1
DE69427695D1 DE69427695T DE69427695T DE69427695D1 DE 69427695 D1 DE69427695 D1 DE 69427695D1 DE 69427695 T DE69427695 T DE 69427695T DE 69427695 T DE69427695 T DE 69427695T DE 69427695 D1 DE69427695 D1 DE 69427695D1
Authority
DE
Germany
Prior art keywords
new procedure
procedure
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69427695T
Other languages
English (en)
Other versions
DE69427695T2 (de
Inventor
Donald Bruce Macmichael
David Drake
Adrian Arlington
Ian David Normansell
John Kenneth Addicott
Moira Sloan Divers
John Spencer Stovold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE69427695D1 publication Critical patent/DE69427695D1/de
Publication of DE69427695T2 publication Critical patent/DE69427695T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/04Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00279Features relating to reactor vessels
    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00457Dispensing or evacuation of the solid phase support
    • B01J2219/00459Beads
    • B01J2219/00468Beads by manipulation of individual beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00603Making arrays on substantially continuous surfaces
    • B01J2219/00659Two-dimensional arrays
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/149Optical investigation techniques, e.g. flow cytometry specially adapted for sorting particles, e.g. by their size or optical properties
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465Separating and mixing arrangements
    • G01N2035/00564Handling or washing solid phase elements, e.g. beads
    • G01N2035/00574Means for distributing beads

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69427695T 1993-05-21 1994-05-17 Neues verfahren und geraet Expired - Lifetime DE69427695T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939310557A GB9310557D0 (en) 1993-05-21 1993-05-21 Novel process and apparatus
PCT/EP1994/001641 WO1994028119A1 (en) 1993-05-21 1994-05-17 Novel process and apparatus

Publications (2)

Publication Number Publication Date
DE69427695D1 true DE69427695D1 (de) 2001-08-16
DE69427695T2 DE69427695T2 (de) 2002-05-08

Family

ID=10735927

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427695T Expired - Lifetime DE69427695T2 (de) 1993-05-21 1994-05-17 Neues verfahren und geraet

Country Status (7)

Country Link
US (1) US5914262A (de)
EP (1) EP0700434B1 (de)
JP (1) JP3626185B2 (de)
AU (1) AU6844694A (de)
DE (1) DE69427695T2 (de)
GB (1) GB9310557D0 (de)
WO (1) WO1994028119A1 (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19520298A1 (de) * 1995-06-02 1996-12-05 Bayer Ag Sortiervorrichtung für biologische Zellen oder Viren
IL117605A0 (en) * 1996-03-21 1996-07-23 Markman Ofer Multi-antigen serological diagnosis
JP2000512541A (ja) * 1996-06-14 2000-09-26 ユニバーシティ オブ ワシントン 吸収力が向上した差違抽出装置
GB9625150D0 (en) * 1996-12-04 1997-01-22 Smithkline Beecham Plc Novel device
CA2278146A1 (en) * 1997-01-17 1998-07-23 John Gerald Gleason Apparatus and process for arraying beads
WO1998041869A1 (en) * 1997-03-18 1998-09-24 Chromaxome Corporation Methods for screening compounds using encapsulated cells
GB9707096D0 (en) * 1997-04-08 1997-05-28 Smithkline Beecham Plc Novel device
JPH11235536A (ja) * 1998-02-23 1999-08-31 Takeda Chem Ind Ltd ビーズセパレータ
US20020028434A1 (en) * 2000-09-06 2002-03-07 Guava Technologies, Inc. Particle or cell analyzer and method
AUPR846501A0 (en) * 2001-10-26 2001-11-15 Btf Pty Ltd A cytometer
US7252987B2 (en) * 2001-12-06 2007-08-07 Islet Technology, Inc. System for analysis and selection of encapsulated cellular materials
WO2006007701A1 (en) * 2004-07-16 2006-01-26 Simon Fraser University Microfluidic device and method of using same
CN101116086A (zh) 2004-11-16 2008-01-30 伊路敏纳公司 读取编码微珠的方法和设备
US8017395B2 (en) 2004-12-17 2011-09-13 Lifescan, Inc. Seeding cells on porous supports
AU2006202209B2 (en) * 2005-05-27 2011-04-14 Lifescan, Inc. Amniotic fluid derived cells
PL1888123T3 (pl) * 2005-06-08 2013-06-28 Janssen Biotech Inc Terapia komórkowa chorób degeneracyjnych oka
CN100344744C (zh) * 2005-11-18 2007-10-24 沈阳农业大学 固态发酵真菌孢子分离器及分离方法
US7830575B2 (en) 2006-04-10 2010-11-09 Illumina, Inc. Optical scanner with improved scan time
US8741643B2 (en) 2006-04-28 2014-06-03 Lifescan, Inc. Differentiation of pluripotent stem cells to definitive endoderm lineage
US9080145B2 (en) * 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
CA3114827C (en) 2007-07-31 2023-09-05 Lifescan, Inc. Differentiation of human embryonic stem cells to pancreatic endocrine
WO2009070592A2 (en) * 2007-11-27 2009-06-04 Lifescan, Inc. Differentiation of human embryonic stem cells
US10066203B2 (en) 2008-02-21 2018-09-04 Janssen Biotech Inc. Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
US8623648B2 (en) * 2008-04-24 2014-01-07 Janssen Biotech, Inc. Treatment of pluripotent cells
KR20180018839A (ko) 2008-06-30 2018-02-21 얀센 바이오테크 인코포레이티드 만능 줄기 세포의 분화
EP2318516A1 (de) * 2008-06-30 2011-05-11 Centocor Ortho Biotech Inc. Differenzierung pluripotenter stammzellen
US20100028307A1 (en) * 2008-07-31 2010-02-04 O'neil John J Pluripotent stem cell differentiation
CN102186970A (zh) 2008-09-12 2011-09-14 克里奥普拉斯低温生物有限公司 缺血性组织的细胞疗法
CN107904201B (zh) 2008-10-31 2021-11-16 詹森生物科技公司 人胚胎干细胞向胰腺内分泌谱系的分化
ES2727950T3 (es) 2008-10-31 2019-10-21 Janssen Biotech Inc Diferenciación de células madre embrionarias humanas en linaje endocrino pancreático
ES2584053T3 (es) * 2008-11-20 2016-09-23 Janssen Biotech, Inc. Métodos y composiciones para la unión de células y cultivo en sustratos planos
MX356756B (es) 2008-11-20 2018-06-11 Centocor Ortho Biotech Inc Células madre pluripotentes en microportadores.
JP5400397B2 (ja) * 2009-01-07 2014-01-29 古河電気工業株式会社 バンドルファイバ及び内視鏡システム
US8383347B1 (en) 2009-05-01 2013-02-26 University Of South Florida Method of diagnosing or assessing risk for Parkinson's disease or Alzheimer's disease using TCR clonality
MX348077B (es) 2009-07-20 2017-05-25 Janssen Biotech Inc Diferenciacion de celulas madre embrionarias humanas.
EP2456858B1 (de) * 2009-07-20 2018-08-29 Janssen Biotech, Inc. Differenzierung menschlicher embryonischer stammzellen
WO2011011349A2 (en) * 2009-07-20 2011-01-27 Centocor Ortho Biotech Inc. Differentiation of human embryonic stem cells
WO2011059725A2 (en) * 2009-10-29 2011-05-19 Centocor Ortho Biotech Inc. Pluripotent stem cells
SG181822A1 (en) * 2009-12-23 2012-08-30 Centocor Ortho Biotech Inc Differentiation of human embryonic stem cells
KR101773538B1 (ko) * 2009-12-23 2017-08-31 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
KR101928299B1 (ko) 2010-03-01 2018-12-12 얀센 바이오테크 인코포레이티드 만능 줄기 세포로부터 유래된 세포의 정제 방법
US20110253603A1 (en) * 2010-04-15 2011-10-20 Van De Loo Philip Karel Marie-Louise Device for inspecting and transferring eggs and a method applied to this end
KR101986176B1 (ko) 2010-05-12 2019-06-05 얀센 바이오테크 인코포레이티드 인간 배아 줄기 세포의 분화
JP6168991B2 (ja) 2010-08-31 2017-07-26 ヤンセン バイオテツク,インコーポレーテツド ヒト胚性幹細胞の分化
EP2611910B1 (de) 2010-08-31 2018-01-17 Janssen Biotech, Inc. Differenzierung menschlicher embryonischer stammzellen
AU2011296383B2 (en) 2010-08-31 2016-03-10 Janssen Biotech, Inc. Differentiation of pluripotent stem cells
US8871500B2 (en) * 2011-01-21 2014-10-28 Innovative Micro Technology MEMS particle sorting actuator and method of manufacturing
WO2013095953A1 (en) 2011-12-22 2013-06-27 Janssen Biotech, Inc. Differentiation of human embryonic stem cells into single hormonal insulin positive cells
EP2823037A4 (de) 2012-03-07 2015-09-16 Janssen Biotech Inc Definierte medien zur expansion und pflege pluripotenter stammzellen
CN108034633B (zh) 2012-06-08 2022-08-02 詹森生物科技公司 人胚胎干细胞向胰腺内分泌细胞的分化
WO2014105543A1 (en) 2012-12-31 2014-07-03 Janssen Biotech, Inc. Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
RU2018108090A (ru) 2012-12-31 2019-02-25 Янссен Байотек, Инк. Суспендирование и кластеризация плюрипотентных клеток человека с целью их дифференцировки в панкреатические эндокринные клетки
DK2938723T3 (da) 2012-12-31 2023-02-20 Janssen Biotech Inc Differentiering af humane embryonale stamceller til pancreatiske endokrine celler under anvendelse af hb9-regulatorer
KR102162138B1 (ko) 2014-05-16 2020-10-06 얀센 바이오테크 인코포레이티드 췌장 내분비 세포에서 mafa 발현을 향상시키기 위한 소분자의 용도
WO2016044721A1 (en) 2014-09-19 2016-03-24 Regenerative Medical Solutions, Inc. Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells
MA45479A (fr) 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
EP3717889B1 (de) * 2017-11-27 2022-04-20 Ecole Polytechnique Fédérale de Lausanne (EPFL) Vorrichtung zum sortieren von biologischen einheiten
JP7511825B2 (ja) * 2019-11-19 2024-07-08 国立大学法人信州大学 アーバスキュラー菌根菌の培養方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2716095C2 (de) * 1977-04-12 1987-02-19 Becton, Dickinson and Co., Paramus, N.J. Verfahren zur Steuerung der Bewegungsbahn von in einem Elektrolyten suspendierten Teilchen und Vorrichtung zur Durchführung dieses Verfahrens
SE441009B (sv) * 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
DE3574617D1 (de) * 1984-09-11 1990-01-11 Partec Ag Verfahren und vorrichtung zur sortierung von mikroskopischen partikeln.
IL79052A0 (en) * 1986-06-06 1986-11-30 Univ Ramot Device and process for production of alginate-shell beads containing biologically active material
US5030002A (en) * 1989-08-11 1991-07-09 Becton, Dickinson And Company Method and apparatus for sorting particles with a moving catcher tube
US5277320A (en) * 1992-01-21 1994-01-11 Seymour, Inc. Shell egg culling system

Also Published As

Publication number Publication date
EP0700434A1 (de) 1996-03-13
WO1994028119A1 (en) 1994-12-08
US5914262A (en) 1999-06-22
JP3626185B2 (ja) 2005-03-02
DE69427695T2 (de) 2002-05-08
EP0700434B1 (de) 2001-07-11
JPH08510380A (ja) 1996-11-05
AU6844694A (en) 1994-12-20
GB9310557D0 (en) 1993-07-07

Similar Documents

Publication Publication Date Title
DE69427695D1 (de) Neues verfahren und geraet
DE69421505D1 (de) Mischvorrichtung und Verfahren
DE69404414D1 (de) Reinigungsverfahren und Reinigungsgerät
DE69622999D1 (de) Pultrusionsvorrichtung und verfahren
DE69523670D1 (de) Anzeigeverfahren und -gerät
DE69824360D1 (de) Peripheriegerät und entsprechendes Verfahren
DE69419423D1 (de) Verfahren zur verkapselung und daraus hergestellte mikrokapseln
DE69608880D1 (de) Testsatz und verfahren
DE69619826D1 (de) Abtastvorrichtung und verfahren
DE69809213D1 (de) Telekommunikationsgerät und verfahren
DE69834401D1 (de) Businterfacesystem und verfahren
DE69421558D1 (de) Übertragungsvorrichtung und Verfahren
DE69318944D1 (de) Lagebestimmungssystem und Verfahren
DE69434376D1 (de) Videotrainingsverfahren und display
DE4497968T1 (de) Abbildungsverfahren und Abbildungseinrichtung
FI940870A0 (fi) Puhdistusmenetelmä ja -laite
DE19581855T1 (de) Schlagvorrichtung und Schlagverfahren
DE69422130D1 (de) Osteometrie und osteometrische vorrichtung
DE69430044D1 (de) Graphenanzeigevorrichtung und -verfahren
DE69332428D1 (de) Angiographie-Apparat und -verfahren
KR960013620A (ko) 성형 방법 및 성형 장치
DE69517913D1 (de) Fixiervorrichtung und Fixierverfahren
DE69515762D1 (de) Bilderzeugungsgerät und Verfahren
DE69420687D1 (de) Anzeigevorrichtung und -verfahren
DE69826804D1 (de) Flüssigkeitverteilvorrichtung und Verfahren

Legal Events

Date Code Title Description
8364 No opposition during term of opposition