DE69420179D1 - 2-Aminopyrazin-5-carbonsäureamid Derivate, deren Herstellung und deren Verwendung als Heilmittel - Google Patents

2-Aminopyrazin-5-carbonsäureamid Derivate, deren Herstellung und deren Verwendung als Heilmittel

Info

Publication number: DE69420179D1
Authority: DE; Germany
Prior art keywords: group; hydrogen atom; optionally substituted; aminopyrazine; medicines
Prior art date: 1993-05-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69420179T

Other languages

English (en)

Inventor

Pascal George

Benoit Marabout

Jacques Froissant

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Synthelabo SA

Original Assignee

Synthelabo SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-17

Filing date

1994-05-10

Publication date

1999-09-30

1994-05-10 Application filed by Synthelabo SA filed Critical Synthelabo SA

1999-09-30 Application granted granted Critical

1999-09-30 Publication of DE69420179D1 publication Critical patent/DE69420179D1/de

2014-05-11 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DE69420179T 1993-05-17 1994-05-10 2-Aminopyrazin-5-carbonsäureamid Derivate, deren Herstellung und deren Verwendung als Heilmittel Expired - Lifetime DE69420179D1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9305930A FR2705344B1 (fr)	1993-05-17	1993-05-17	Dérivés de 2-aminopyrazine-5-carboxamide, leur préparation et leur application en thérapeutique.

Publications (1)

Publication Number	Publication Date
DE69420179D1 true DE69420179D1 (de)	1999-09-30

Family

ID=9447217

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69420179T Expired - Lifetime DE69420179D1 (de)	1993-05-17	1994-05-10	2-Aminopyrazin-5-carbonsäureamid Derivate, deren Herstellung und deren Verwendung als Heilmittel

Country Status (19)

Country	Link
US (1)	US5420130A (de)
EP (1)	EP0625514B1 (de)
JP (1)	JPH06329645A (de)
CN (1)	CN1104637A (de)
AT (1)	ATE183742T1 (de)
AU (1)	AU671361B2 (de)
CA (1)	CA2123668A1 (de)
CZ (1)	CZ283499B6 (de)
DE (1)	DE69420179D1 (de)
FI (1)	FI942265L (de)
FR (1)	FR2705344B1 (de)
HU (1)	HUT69711A (de)
IL (1)	IL109655A (de)
NO (1)	NO941830L (de)
NZ (1)	NZ260531A (de)
PL (1)	PL173309B1 (de)
RU (1)	RU2128176C1 (de)
SK (1)	SK57494A3 (de)
ZA (1)	ZA943353B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1075486A1 (de) *	1998-05-06	2001-02-14	Duke University	Verfahren zur behandlung von syndromen der niere und der unteren harnwege
CN1275947C (zh)	1998-08-20	2006-09-20	富山化学工业株式会社	含氮杂环羧酰胺衍生物或其盐

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4041032A (en) *	1974-01-16	1977-08-09	Yamanouchi Pharmaceutical Co., Ltd.	Pyrazine derivatives
GB8712365D0 (en) *	1987-05-26	1987-07-01	Ici America Inc	Aminomethylphenolic pyrazines
FR2656609B1 (fr) *	1989-12-28	1992-03-27	Synthelabo	Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique.

1993
- 1993-05-17 FR FR9305930A patent/FR2705344B1/fr not_active Expired - Fee Related
1994
- 1994-05-10 DE DE69420179T patent/DE69420179D1/de not_active Expired - Lifetime
- 1994-05-10 AT AT94401032T patent/ATE183742T1/de not_active IP Right Cessation
- 1994-05-10 EP EP94401032A patent/EP0625514B1/de not_active Expired - Lifetime
- 1994-05-15 IL IL10965594A patent/IL109655A/en not_active IP Right Cessation
- 1994-05-16 PL PL94303478A patent/PL173309B1/pl unknown
- 1994-05-16 CA CA002123668A patent/CA2123668A1/en not_active Abandoned
- 1994-05-16 RU RU94016363A patent/RU2128176C1/ru active
- 1994-05-16 US US08/243,315 patent/US5420130A/en not_active Expired - Fee Related
- 1994-05-16 ZA ZA943353A patent/ZA943353B/xx unknown
- 1994-05-16 NZ NZ260531A patent/NZ260531A/en unknown
- 1994-05-16 NO NO941830A patent/NO941830L/no unknown
- 1994-05-16 CN CN94105541A patent/CN1104637A/zh active Pending
- 1994-05-16 CZ CZ941195A patent/CZ283499B6/cs unknown
- 1994-05-16 AU AU63126/94A patent/AU671361B2/en not_active Ceased
- 1994-05-16 JP JP6100999A patent/JPH06329645A/ja active Pending
- 1994-05-16 SK SK574-94A patent/SK57494A3/sk unknown
- 1994-05-16 HU HU9401512A patent/HUT69711A/hu unknown
- 1994-05-16 FI FI942265A patent/FI942265L/fi unknown

Also Published As

Publication number	Publication date
CA2123668A1 (en)	1994-11-18
FR2705344B1 (fr)	1995-06-30
NO941830D0 (no)	1994-05-16
PL173309B1 (pl)	1998-02-27
US5420130A (en)	1995-05-30
RU94016363A (ru)	1996-04-10
HU9401512D0 (en)	1994-08-29
NO941830L (no)	1994-11-18
FR2705344A1 (fr)	1994-11-25
ATE183742T1 (de)	1999-09-15
IL109655A0 (en)	1994-08-26
IL109655A (en)	1999-03-12
RU2128176C1 (ru)	1999-03-27
SK57494A3 (en)	1995-07-11
CZ283499B6 (cs)	1998-04-15
AU671361B2 (en)	1996-08-22
EP0625514A1 (de)	1994-11-23
HUT69711A (en)	1995-09-28
NZ260531A (en)	1995-10-26
FI942265A0 (fi)	1994-05-16
AU6312694A (en)	1994-11-24
JPH06329645A (ja)	1994-11-29
FI942265A7 (fi)	1994-11-18
EP0625514B1 (de)	1999-08-25
FI942265L (fi)	1994-11-18
CN1104637A (zh)	1995-07-05
ZA943353B (en)	1995-03-28
CZ119594A3 (en)	1994-12-15

Publication	Publication Date	Title
NO924783L (no)	1993-02-23	Terapeutiske midler
TR200000736T2 (tr)	2000-07-21	İkame edilmiş kroman türevleri.
DE68903680D1 (de)	1993-01-14	6-phenyl-3-piperazinylalkyl-1h,3h-pyrimidindion-2,4-derivate, deren herstellung und verwendung als heilmittel.
DE69410509D1 (de)	1998-07-02	Benzoxazinderivate, deren Herstellung und deren Verwendung in Therapie
ATE111460T1 (de)	1994-09-15	2-(aminoalkyl)-5-(arylalkyl)1,3-dioxanderivate, ihre herstellung und ihre anwendung in der therapeutik.
ATE83234T1 (de)	1992-12-15	Oxadiazol-pyrimidinone, ihre herstellung und ihre kosmetische und dermopharmazeutische verwendung.
ATE80384T1 (de)	1992-09-15	Sulfurierte eicosanoide und deren verwendung in arzneimitteln und kosmetika.
DE69420179D1 (de)	1999-09-30	2-Aminopyrazin-5-carbonsäureamid Derivate, deren Herstellung und deren Verwendung als Heilmittel
ATE123025T1 (de)	1995-06-15	2-amino-n-(((4-(aminocarbonyl)pyrimidin-2- yl>amino>alkyl>-pyrimidin-4- carbonsäureamidderivate, ihre herstellung und ihre anwendung in der therapeutica.
ATE33134T1 (de)	1988-04-15	2-aminoethyl-pyridin oder pyrazin-derivate, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE2786T1 (de)	1983-04-15	1-(2-propynyloxy)-2-amino-3-propanol-aether, ihre herstellung und sie enthaltende pharmazeutische zusammensetzung.
DE69523640D1 (de)	2001-12-06	Substituierte 6-r-1,3,4-thiadiazin-2-amine, deren verwendung als anaesthetische, cardiovaskulare und hypometabolische mittel, und eine sie enthaltende pharmazeutische zubereitung
ATE134607T1 (de)	1996-03-15	Tetrahydronaphtalenderivate, ihre herstellung und ihre therapeutische verwendung
ATE213415T1 (de)	2002-03-15	Substituierte 6-h-1,3,4,-thiadiazin-2-amine, deren verwendung als anaesthetisierende, cardiovaskulare und hypometabolische mittel, und eine sie enthaltende pharmazeutische zubereitung

Legal Events

Date	Code	Title	Description
2000-03-09	8332	No legal effect for de