DE69409643D1 - Verfahren, agenzien und kits zum nachweis von phosphororganischen verbindungen - Google Patents
Verfahren, agenzien und kits zum nachweis von phosphororganischen verbindungenInfo
- Publication number
- DE69409643D1 DE69409643D1 DE69409643T DE69409643T DE69409643D1 DE 69409643 D1 DE69409643 D1 DE 69409643D1 DE 69409643 T DE69409643 T DE 69409643T DE 69409643 T DE69409643 T DE 69409643T DE 69409643 D1 DE69409643 D1 DE 69409643D1
- Authority
- DE
- Germany
- Prior art keywords
- antibodies
- protein
- methods
- methyl
- raising
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 238000000034 method Methods 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 239000000575 pesticide Substances 0.000 abstract 2
- 108091003079 Bovine Serum Albumin Proteins 0.000 abstract 1
- FGIWFCGDPUIBEZ-UHFFFAOYSA-N Etrimfos Chemical compound CCOC1=CC(OP(=S)(OC)OC)=NC(CC)=N1 FGIWFCGDPUIBEZ-UHFFFAOYSA-N 0.000 abstract 1
- 239000005949 Malathion Substances 0.000 abstract 1
- NTAHCMPOMKHKEU-AATRIKPKSA-N Methacrifos Chemical compound COC(=O)C(\C)=C\OP(=S)(OC)OC NTAHCMPOMKHKEU-AATRIKPKSA-N 0.000 abstract 1
- 108010058846 Ovalbumin Proteins 0.000 abstract 1
- 241000237988 Patellidae Species 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 229940098773 bovine serum albumin Drugs 0.000 abstract 1
- 210000000991 chicken egg Anatomy 0.000 abstract 1
- OEBRKCOSUFCWJD-UHFFFAOYSA-N dichlorvos Chemical compound COP(=O)(OC)OC=C(Cl)Cl OEBRKCOSUFCWJD-UHFFFAOYSA-N 0.000 abstract 1
- JXSJBGJIGXNWCI-UHFFFAOYSA-N diethyl 2-[(dimethoxyphosphorothioyl)thio]succinate Chemical compound CCOC(=O)CC(SP(=S)(OC)OC)C(=O)OCC JXSJBGJIGXNWCI-UHFFFAOYSA-N 0.000 abstract 1
- ZNOLGFHPUIJIMJ-UHFFFAOYSA-N fenitrothion Chemical compound COP(=S)(OC)OC1=CC=C([N+]([O-])=O)C(C)=C1 ZNOLGFHPUIJIMJ-UHFFFAOYSA-N 0.000 abstract 1
- 229960000453 malathion Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940092253 ovalbumin Drugs 0.000 abstract 1
- 125000006850 spacer group Chemical group 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/16—Esters of thiophosphoric acids or thiophosphorous acids
- C07F9/165—Esters of thiophosphoric acids
- C07F9/1651—Esters of thiophosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/58—Pyridine rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Luminescent Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB939310238A GB9310238D0 (en) | 1993-05-18 | 1993-05-18 | Method,agents and kits for detection of organic agents |
| PCT/GB1994/001060 WO1994027149A1 (en) | 1993-05-18 | 1994-05-18 | Methods, agents and kits for detection of organophosphorus compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69409643D1 true DE69409643D1 (de) | 1998-05-20 |
| DE69409643T2 DE69409643T2 (de) | 1998-08-06 |
Family
ID=10735700
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69409643T Expired - Fee Related DE69409643T2 (de) | 1993-05-18 | 1994-05-18 | Verfahren, agenzien und kits zum nachweis von phosphororganischen verbindungen |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US5830770A (de) |
| EP (1) | EP0699305B1 (de) |
| JP (1) | JPH08510231A (de) |
| AT (1) | ATE165165T1 (de) |
| AU (1) | AU6656694A (de) |
| DE (1) | DE69409643T2 (de) |
| DK (1) | DK0699305T3 (de) |
| ES (1) | ES2114686T3 (de) |
| GB (2) | GB9310238D0 (de) |
| GR (1) | GR3026668T3 (de) |
| WO (1) | WO1994027149A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9310238D0 (en) * | 1993-05-18 | 1993-07-14 | Mini Agriculture & Fisheries | Method,agents and kits for detection of organic agents |
| GB9515850D0 (en) * | 1995-08-02 | 1995-10-04 | Mini Agriculture & Fisheries | Broad specificity antibodies |
| US6635434B1 (en) | 1999-09-17 | 2003-10-21 | Exiqon A/S | Immunoassay for pesticides and their degradation products |
| JP2001275682A (ja) * | 2000-03-31 | 2001-10-09 | Kankyo Meneki Gijutsu Kenkyusho:Kk | 抗マラチオンモノクローナル抗体をコードする遺伝子 |
| US20020193685A1 (en) * | 2001-06-08 | 2002-12-19 | Calypso Medical, Inc. | Guided Radiation Therapy System |
| KR100423526B1 (ko) * | 2001-12-28 | 2004-03-18 | 이용태 | 유기인계 포스포로티오에이트 류 농약의 면역분석적검출에 이용되는 합텐의 제조방법 |
| KR100644205B1 (ko) | 2005-06-30 | 2006-11-10 | 이용태 | 유기인계 농약의 총체적 검출을 위한 합텐과 항체 및 이를이용한 면역분석방법 |
| CA2669571A1 (en) * | 2006-11-13 | 2008-07-03 | Ateris Technologies, Llc | Pesticide biomarker |
| WO2009064321A2 (en) * | 2007-11-14 | 2009-05-22 | Ateris Technologies. Llc | Biomarker detection |
| CN104262486B (zh) * | 2014-09-24 | 2017-03-15 | 江苏省农业科学院 | 杂交瘤细胞株fq‑2g3，其产生的抗甲基毒死蜱单克隆抗体及免疫层析试纸条 |
| CN107064494B (zh) * | 2017-04-17 | 2019-12-24 | 四川精卫食品检测科技有限公司 | 一种毒死蜱检测酶联免疫试剂盒 |
| CN110684110A (zh) * | 2019-09-20 | 2020-01-14 | 北京勤邦生物技术有限公司 | 一种甲基嘧啶磷单克隆抗体的制备及其应用 |
| CN110981907A (zh) * | 2019-11-05 | 2020-04-10 | 华南农业大学 | 一种马拉硫磷半抗原、人工抗原及其制备方法 |
| CN113388037B (zh) * | 2021-04-14 | 2022-04-29 | 华南农业大学 | 一种特异性识别杀螟硫磷纳米抗体的制备及其应用 |
| CN114720525B (zh) * | 2022-03-22 | 2024-01-05 | 华南农业大学 | 一种对硫磷免疫传感器及其制备方法与应用 |
| WO2023250034A1 (en) * | 2022-06-21 | 2023-12-28 | Thompson Charles M | Antibody-assisted detoxication of reactive organophosphorus compounds |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5413915A (en) * | 1988-07-12 | 1995-05-09 | Resource Technologies Group, Inc. | Method and sensor for detecting toxic chemical exposure effects and metabolic activation of carcinogenic chemical agents |
| ATE186553T1 (de) * | 1989-06-30 | 1999-11-15 | Commw Scient Ind Res Org | Competitives enzym-testverfahren zum nachweis von phosphothioaten |
| JP3370090B2 (ja) * | 1990-06-15 | 2003-01-27 | ヘキスト・アクチェンゲゼルシャフト | 抗菌性ポリペプチドおよびその製法 |
| US5283180A (en) * | 1990-07-19 | 1994-02-01 | Charm Sciences, Inc. | Bioluminescence method for the determination of pesticides |
| GB9310238D0 (en) * | 1993-05-18 | 1993-07-14 | Mini Agriculture & Fisheries | Method,agents and kits for detection of organic agents |
-
1993
- 1993-05-18 GB GB939310238A patent/GB9310238D0/en active Pending
-
1994
- 1994-05-18 DK DK94915246T patent/DK0699305T3/da active
- 1994-05-18 GB GB9522508A patent/GB2293384B/en not_active Revoked
- 1994-05-18 EP EP94915246A patent/EP0699305B1/de not_active Expired - Lifetime
- 1994-05-18 AU AU66566/94A patent/AU6656694A/en not_active Abandoned
- 1994-05-18 JP JP6525185A patent/JPH08510231A/ja active Pending
- 1994-05-18 US US08/557,003 patent/US5830770A/en not_active Expired - Fee Related
- 1994-05-18 DE DE69409643T patent/DE69409643T2/de not_active Expired - Fee Related
- 1994-05-18 AT AT94915246T patent/ATE165165T1/de not_active IP Right Cessation
- 1994-05-18 ES ES94915246T patent/ES2114686T3/es not_active Expired - Lifetime
- 1994-05-18 WO PCT/GB1994/001060 patent/WO1994027149A1/en active IP Right Grant
-
1998
- 1998-04-16 GR GR980400626T patent/GR3026668T3/el unknown
- 1998-05-01 US US09/070,748 patent/US6133049A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| GB9310238D0 (en) | 1993-07-14 |
| GR3026668T3 (en) | 1998-07-31 |
| DK0699305T3 (da) | 1998-11-23 |
| ATE165165T1 (de) | 1998-05-15 |
| WO1994027149A1 (en) | 1994-11-24 |
| GB9522508D0 (en) | 1996-01-03 |
| US5830770A (en) | 1998-11-03 |
| GB2293384A (en) | 1996-03-27 |
| JPH08510231A (ja) | 1996-10-29 |
| EP0699305A1 (de) | 1996-03-06 |
| AU6656694A (en) | 1994-12-12 |
| ES2114686T3 (es) | 1998-06-01 |
| US6133049A (en) | 2000-10-17 |
| GB2293384B (en) | 1997-05-14 |
| DE69409643T2 (de) | 1998-08-06 |
| EP0699305B1 (de) | 1998-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69409643D1 (de) | Verfahren, agenzien und kits zum nachweis von phosphororganischen verbindungen | |
| FI891012A0 (fi) | Menetelmä ja väline immuunikokeissa esiintyvien häiriötekijöiden kompensoimiseksi | |
| ATE98376T1 (de) | Synthetische htlv-iii-peptid-zusammensetzungen und ihre verwendung. | |
| ATE96679T1 (de) | Makromolekulare platin-antitumorverbindungen. | |
| DE69228682D1 (de) | "crosstalk"- oder übersprech-inhibitoren und ihre verwendung | |
| ES2045152T3 (es) | Derivados de lipidos, su preparacion y uso. | |
| ES2059408T3 (es) | Un proceso para la preparacion de un compuesto. | |
| DE3865767D1 (de) | Vorrichtung zum auffangen von kraftstoffdaempfen. | |
| DE69030789D1 (de) | Ausgleichsgewichtssystem für Brennkraftmaschine | |
| ATE48157T1 (de) | Ein zwitterion als bindungsmittel enthaltende zusammensetzung und testvorrichtung zum nachweis von leukozyten. | |
| DK0770876T3 (da) | En screening-fremgangsmåde til at identificere ligander for målproteiner | |
| KR910700242A (ko) | 간섭 결합제 및 그 방법 | |
| DE69526521D1 (de) | Modulation der immunantwort | |
| DE3882259D1 (de) | Apparat zur behandlung von verbrennungsabgas. | |
| ATE44621T1 (de) | Proteinkonjugate von penicillosaeure, ihre herstellung und verwendung. | |
| SE8600641L (sv) | Nitrilofora eda-absorbenter | |
| Moskalenko et al. | Investigation of the neighbour relationships between photosystem II polypeptides in the two types of isolated reaction centres (D1/D2/cytb 559 and CP47/D1/D2/cyt b 559 complexes) | |
| DE68909515D1 (de) | Durch antikoerper und liganden bewirkte zielrichtung von differentiationsinduktoren auf tumorzellen. | |
| FI922710A0 (fi) | Eliminering av aktiverade lymfocyter. | |
| Moskalenko et al. | Investigation of the neighbour relationships between photosystem II polypeptides in the two t! rpes of isolated reaction centres (IX/D2/cytbss9 and CP47/Dl/D2/cyt bsss complexes) | |
| DK288389D0 (da) | Fremgangsmaade til paavisning af marek-virus hos fjerkrae og saet til udfoerelse af fremgangsmaaden | |
| ATE56212T1 (de) | Verfahren zur herstellung von pyrrolopyridinderivaten und so erhaltene derivate. | |
| ATE66671T1 (de) | Gamma-l-glutanyl-4-nitoanilid-derivate und verfahren zur bestimmung von gamma-gtp-aktivitaet unter verwendung dieser derivate. | |
| ES2033445T3 (es) | Nuevo procedimiento de dosificacion simultaneo de por lo menos dos subconjuntos de apolipoproteinas contenidas en un medio biologico. | |
| DE3853677D1 (de) | Silylgruppen enthaltende Aminverbindungen zur Verwendung als antimikrobische Wirkstoffe. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |