DE68903907D1 - Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen. - Google Patents
Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen.Info
- Publication number
- DE68903907D1 DE68903907D1 DE8989308901T DE68903907T DE68903907D1 DE 68903907 D1 DE68903907 D1 DE 68903907D1 DE 8989308901 T DE8989308901 T DE 8989308901T DE 68903907 T DE68903907 T DE 68903907T DE 68903907 D1 DE68903907 D1 DE 68903907D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- cyclic peptide
- cardiovascular disorders
- treating cardiovascular
- hapsidospora
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 208000024172 Cardiovascular disease Diseases 0.000 title abstract 3
- 108010069514 Cyclic Peptides Proteins 0.000 title 1
- 102000001189 Cyclic Peptides Human genes 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000369650 Hapsidospora Species 0.000 abstract 1
- 241000369647 Hapsidospora irregularis Species 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- HHNHRFWUTDSIPH-UHFFFAOYSA-N Leualacin Natural products CN1C(=O)C(CC(C)C)OC(=O)C(CC(C)C)NC(=O)C(CC(C)C)OC(=O)CCNC(=O)C1CC1=CC=CC=C1 HHNHRFWUTDSIPH-UHFFFAOYSA-N 0.000 abstract 1
- 108010049006 leualacin Proteins 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K11/00—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K11/02—Depsipeptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof cyclic, e.g. valinomycins ; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/80—Antihypertensive peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Botany (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP22196088 | 1988-09-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68903907D1 true DE68903907D1 (de) | 1993-01-28 |
DE68903907T2 DE68903907T2 (de) | 1993-06-09 |
Family
ID=16774855
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8989308901T Expired - Fee Related DE68903907T2 (de) | 1988-09-05 | 1989-09-01 | Cyclisches peptid, seine herstellung und seine verwendung zur behandlung von cardiovasculaeren stoerungen. |
Country Status (6)
Country | Link |
---|---|
US (1) | US5112807A (de) |
EP (1) | EP0358418B1 (de) |
AT (1) | ATE83480T1 (de) |
DE (1) | DE68903907T2 (de) |
ES (1) | ES2054011T3 (de) |
GR (1) | GR3007079T3 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9302046D0 (en) * | 1993-02-03 | 1993-03-24 | Pharma Mar Sa | Antiumoral compound-v |
US5461070A (en) * | 1994-08-29 | 1995-10-24 | The Regents Of The University Of California | Anti-flammatory method using indole alkaloids |
SI2376101T1 (sl) | 2008-12-29 | 2016-02-29 | Trevena, Inc. | Efektorji beta-arestina in sestavki ter metode za njihovo uporabo |
JP6225121B2 (ja) * | 2012-01-31 | 2017-11-01 | トレベナ・インコーポレイテッドTrevena, Inc. | β−アレスチンエフェクターおよび組成物ならびにそれらの使用方法 |
US9518086B2 (en) | 2014-02-07 | 2016-12-13 | Trevena, Inc. | Crystalline and amorphous forms of a β-arrestin effector |
CN106456698B (zh) | 2014-05-19 | 2022-05-17 | 特维娜有限公司 | β-抑制蛋白效应物的合成 |
CN106892875B (zh) * | 2016-11-11 | 2018-03-02 | 杭州唯铂莱生物科技有限公司 | 钙离子通道阻滞剂化合物及其制备方法和应用 |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2108106B (en) * | 1978-07-04 | 1983-09-01 | Shell Int Research | Novel macrocyclic compounds and salts thereof useful for dissolving barium sulphate scale |
SU1219587A1 (ru) * | 1978-09-29 | 1986-03-23 | Ордена Трудового Красного Знамени Институт Органического Синтеза Ан Латвсср | Циклические аналоги каллидина и других пахикининов,обладающие пролонгированным гипотензивным действием в сочетании с низкой или полностью отсутствующей миотропной активностью |
-
1989
- 1989-09-01 EP EP89308901A patent/EP0358418B1/de not_active Expired - Lifetime
- 1989-09-01 DE DE8989308901T patent/DE68903907T2/de not_active Expired - Fee Related
- 1989-09-01 AT AT89308901T patent/ATE83480T1/de not_active IP Right Cessation
- 1989-09-01 ES ES89308901T patent/ES2054011T3/es not_active Expired - Lifetime
- 1989-09-05 US US07/403,117 patent/US5112807A/en not_active Expired - Fee Related
-
1993
- 1993-02-17 GR GR930400312T patent/GR3007079T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5112807A (en) | 1992-05-12 |
ES2054011T3 (es) | 1994-08-01 |
GR3007079T3 (de) | 1993-07-30 |
EP0358418A1 (de) | 1990-03-14 |
DE68903907T2 (de) | 1993-06-09 |
EP0358418B1 (de) | 1992-12-16 |
ATE83480T1 (de) | 1993-01-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |