[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DE60326348D1 - Makrozyclen zur behandlung von krebserkrankungen - Google Patents

Makrozyclen zur behandlung von krebserkrankungen

Info

Publication number
DE60326348D1
DE60326348D1 DE60326348T DE60326348T DE60326348D1 DE 60326348 D1 DE60326348 D1 DE 60326348D1 DE 60326348 T DE60326348 T DE 60326348T DE 60326348 T DE60326348 T DE 60326348T DE 60326348 D1 DE60326348 D1 DE 60326348D1
Authority
DE
Germany
Prior art keywords
treatment
macrocles
cancer disorders
cancer
disorders
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60326348T
Other languages
English (en)
Inventor
Gerhard Hoefle
Wolfgang Richter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Wolfgang Dr 81243 Muenchen De
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Original Assignee
Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10232094A external-priority patent/DE10232094A1/de
Priority claimed from DE10255660A external-priority patent/DE10255660A1/de
Application filed by Helmholtz Zentrum fuer Infektionsforschung HZI GmbH filed Critical Helmholtz Zentrum fuer Infektionsforschung HZI GmbH
Application granted granted Critical
Publication of DE60326348D1 publication Critical patent/DE60326348D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26Radicals substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06Six-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D497/00Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60326348T 2002-07-15 2003-07-15 Makrozyclen zur behandlung von krebserkrankungen Expired - Lifetime DE60326348D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10232094A DE10232094A1 (de) 2002-07-15 2002-07-15 5-Thiaepothilone und 15-disubstituierte Epothilone
DE10255660A DE10255660A1 (de) 2002-11-28 2002-11-28 Neue Makrocyclen zur Behandlung von Krebserkrankungen
PCT/EP2003/007664 WO2004007492A1 (de) 2002-07-15 2003-07-15 A taper

Publications (1)

Publication Number Publication Date
DE60326348D1 true DE60326348D1 (de) 2009-04-09

Family

ID=30116646

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60326348T Expired - Lifetime DE60326348D1 (de) 2002-07-15 2003-07-15 Makrozyclen zur behandlung von krebserkrankungen

Country Status (10)

Country Link
US (1) US7553859B2 (de)
EP (1) EP1521752B1 (de)
JP (1) JP4597667B2 (de)
AT (1) ATE423780T1 (de)
AU (1) AU2003252540B2 (de)
CA (1) CA2491943C (de)
DE (1) DE60326348D1 (de)
DK (1) DK1521752T3 (de)
ES (1) ES2323956T3 (de)
WO (1) WO2004007492A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1567524T3 (da) * 2002-11-28 2009-11-16 Wolfgang Richter Thia-epothilonderivater til behandling af cancer
CN104116736A (zh) 2008-04-24 2014-10-29 百时美施贵宝公司 埃坡霉素D在治疗包括阿尔茨海默病的τ相关疾病中的用途
EP2394640A1 (de) 2010-05-21 2011-12-14 MediGene AG Verbesserte liposomale Formulierungen von lipophilen Verbindungen
EP2708243A1 (de) 2012-09-17 2014-03-19 OntoChem GmbH Rezeptor-Ligand-verbundene zytotoxische Moleküle

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001243372A1 (en) * 2000-03-01 2001-09-12 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
IL153688A0 (en) * 2000-06-28 2003-07-06 Teva Pharma Carvedilol
DK1567524T3 (da) * 2002-11-28 2009-11-16 Wolfgang Richter Thia-epothilonderivater til behandling af cancer

Also Published As

Publication number Publication date
ATE423780T1 (de) 2009-03-15
AU2003252540A1 (en) 2004-02-02
JP2005537263A (ja) 2005-12-08
CA2491943C (en) 2012-06-19
ES2323956T3 (es) 2009-07-28
WO2004007492A1 (de) 2004-01-22
EP1521752B1 (de) 2009-02-25
JP4597667B2 (ja) 2010-12-15
EP1521752A1 (de) 2005-04-13
DK1521752T3 (da) 2009-06-22
AU2003252540B2 (en) 2008-11-20
US20060004065A1 (en) 2006-01-05
CA2491943A1 (en) 2004-01-22
US7553859B2 (en) 2009-06-30

Similar Documents

Publication Publication Date Title
DE50310516D1 (de) Fredericamycin-derivate
EA200501771A1 (ru) Лиганды каннабиноидных рецепторов и их применения
ATE414089T1 (de) Verwendung von rapamycin und dessen derivaten zur behandlung von knochenverlust
ATE433973T1 (de) Azolylaminoazine als inhibitoren von proteinkinasen
DE602004020072D1 (de) 1,2,3,4-tetrasubstituiertes indol zur behandlung von atemwegserkrankungen
TW200510325A (en) 2-acylamino-4-phenylthiazole derivatives, preparation thereof and therapeutic application thereof
DE60141636D1 (de) Phospholipidderivate von valproinsäure und ihre kombinationen
MY141528A (en) Anilinopyrazole derivatives useful for the treatment of diabetes
DE502004010131D1 (de) Pyridopyrimidinone zur behandlung von krebserkrankungen
DE60021381D1 (de) Chinonverbindungen zur behandlung von krankheiten
NO20055741D0 (no) Nye kjemiske forbindelser
SE0302304D0 (sv) Novel compounds
ATE367380T1 (de) Zur behandlung von zns-erkrankungen geeignete piperazinylchinolinderivate
ATE359283T1 (de) Substituierte pyrazinonverbindungen zur behandlung von entzündungen
DE60329326D1 (de) Tace inhibitoren
NO20055563L (no) Midler for behandlingen av lavere abdominale lidelser
DE602004021363D1 (de) Imidazotriazin verbindungen zur behandlung von krebserkrankungen
DE60131968D1 (de) PYRANOÄ2,3-cÜIMIDAZOÄ1,2-aÜPYRIDIN-DERIVATE ZUR BEHANDLUNG VON GASTROINTESTINALEN ERKRANKUNGEN
ATE361071T1 (de) Verwendung von irbesartan zur vorbeugung oder behandlung pulmonaler hypertonie
DE602004019541D1 (de) Cycloalkyläbü kondensierte indole
DE60326348D1 (de) Makrozyclen zur behandlung von krebserkrankungen
ATE536874T1 (de) Dreifache monoamin-wiederaufnahmehemmer zur behandlung von chronischen schmerzen
DE602005010258D1 (de) Behandlung von ballastwasser
DE60220825D1 (de) Verwendung von norepinephrinwiederaufnahmehemmern zur behandlung von ticks
EA200600115A1 (ru) Производные 2-аминобензойной кислоты

Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: HELMHOLTZ-ZENTRUM FUER INFEKTIONSFORSCHUNG GMB, DE

Owner name: RICHTER, WOLFGANG, DR., 81243 MUENCHEN, DE

8364 No opposition during term of opposition