DE60316547D1 - Doping bei der walk-through-mutagenese - Google Patents
Doping bei der walk-through-mutageneseInfo
- Publication number
- DE60316547D1 DE60316547D1 DE60316547T DE60316547T DE60316547D1 DE 60316547 D1 DE60316547 D1 DE 60316547D1 DE 60316547 T DE60316547 T DE 60316547T DE 60316547 T DE60316547 T DE 60316547T DE 60316547 D1 DE60316547 D1 DE 60316547D1
- Authority
- DE
- Germany
- Prior art keywords
- prototype
- predetermined
- synthesis
- polypeptide
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1089—Design, preparation, screening or analysis of libraries using computer algorithms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37368602P | 2002-04-17 | 2002-04-17 | |
US373686P | 2002-04-17 | ||
PCT/US2003/011935 WO2003089671A1 (en) | 2002-04-17 | 2003-04-16 | 'doping' in walk-through mutagenesis |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60316547D1 true DE60316547D1 (de) | 2007-11-08 |
DE60316547T2 DE60316547T2 (de) | 2008-07-03 |
Family
ID=29251060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60316547T Expired - Lifetime DE60316547T2 (de) | 2002-04-17 | 2003-04-16 | Doping bei der walk-through-mutagenese |
Country Status (12)
Country | Link |
---|---|
US (1) | US20040033569A1 (de) |
EP (1) | EP1495142B1 (de) |
JP (1) | JP4433798B2 (de) |
CN (1) | CN1653193A (de) |
AT (1) | ATE374255T1 (de) |
AU (1) | AU2003228568A1 (de) |
CA (1) | CA2482769C (de) |
DE (1) | DE60316547T2 (de) |
ES (1) | ES2295584T3 (de) |
MX (1) | MXPA04010222A (de) |
NZ (1) | NZ535928A (de) |
WO (1) | WO2003089671A1 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1769003A1 (de) * | 2004-07-06 | 2007-04-04 | Bioren, Inc. | Hochaffine anti-tnf-alpha-antikörper und verfahren |
CA2572961C (en) | 2004-07-06 | 2016-08-16 | Bioren, Inc. | Universal antibody libraries |
ATE528396T1 (de) | 2004-07-06 | 2011-10-15 | Bioren Inc | Look-through-mutagenese zur entwicklung veränderter polypeptide mit verbesserten eigenschaften |
WO2009023184A2 (en) * | 2007-08-10 | 2009-02-19 | Protelix, Inc. | Universal fibronectin type iii binding-domain libraries |
US8680019B2 (en) | 2007-08-10 | 2014-03-25 | Protelica, Inc. | Universal fibronectin Type III binding-domain libraries |
US8470966B2 (en) | 2007-08-10 | 2013-06-25 | Protelica, Inc. | Universal fibronectin type III binding-domain libraries |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5215889A (en) * | 1988-11-18 | 1993-06-01 | The Regents Of The University Of California | Catalytic and reactive polypeptides and methods for their preparation and use |
ATE126535T1 (de) * | 1990-04-05 | 1995-09-15 | Roberto Crea | ''walk-through''-mutagenese. |
JP3764476B2 (ja) * | 1992-06-18 | 2006-04-05 | クリージエン・インコーポレーテツド | 組合せポリペプチド抗原 |
WO1997030150A2 (en) * | 1996-02-15 | 1997-08-21 | Pangenetics B.V. | Molecules for the induction of immunological tolerance |
WO2001048485A2 (en) * | 1999-12-27 | 2001-07-05 | Crucell Holland B.V. | Selecting library members capable of binding to epitopes |
-
2003
- 2003-04-16 EP EP03726328A patent/EP1495142B1/de not_active Expired - Lifetime
- 2003-04-16 WO PCT/US2003/011935 patent/WO2003089671A1/en active IP Right Grant
- 2003-04-16 AT AT03726328T patent/ATE374255T1/de not_active IP Right Cessation
- 2003-04-16 NZ NZ535928A patent/NZ535928A/en unknown
- 2003-04-16 US US10/417,895 patent/US20040033569A1/en not_active Abandoned
- 2003-04-16 MX MXPA04010222A patent/MXPA04010222A/es unknown
- 2003-04-16 DE DE60316547T patent/DE60316547T2/de not_active Expired - Lifetime
- 2003-04-16 AU AU2003228568A patent/AU2003228568A1/en not_active Abandoned
- 2003-04-16 CA CA2482769A patent/CA2482769C/en not_active Expired - Fee Related
- 2003-04-16 ES ES03726328T patent/ES2295584T3/es not_active Expired - Lifetime
- 2003-04-16 CN CN03811148.9A patent/CN1653193A/zh active Pending
- 2003-04-16 JP JP2003586379A patent/JP4433798B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2482769A1 (en) | 2003-10-30 |
JP2005523026A (ja) | 2005-08-04 |
ES2295584T3 (es) | 2008-04-16 |
EP1495142B1 (de) | 2007-09-26 |
CA2482769C (en) | 2013-10-08 |
CN1653193A (zh) | 2005-08-10 |
DE60316547T2 (de) | 2008-07-03 |
WO2003089671A1 (en) | 2003-10-30 |
NZ535928A (en) | 2006-09-29 |
AU2003228568A1 (en) | 2003-11-03 |
US20040033569A1 (en) | 2004-02-19 |
EP1495142A1 (de) | 2005-01-12 |
MXPA04010222A (es) | 2005-03-07 |
JP4433798B2 (ja) | 2010-03-17 |
ATE374255T1 (de) | 2007-10-15 |
EP1495142A4 (de) | 2005-06-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R082 | Change of representative |
Ref document number: 1495142 Country of ref document: EP Representative=s name: MAI DOERR BESIER PATENTANWAELTE, DE |