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DE60224291D1 - System zur antikörperexpression und- synthese - Google Patents

System zur antikörperexpression und- synthese

Info

Publication number
DE60224291D1
DE60224291D1 DE60224291T DE60224291T DE60224291D1 DE 60224291 D1 DE60224291 D1 DE 60224291D1 DE 60224291 T DE60224291 T DE 60224291T DE 60224291 T DE60224291 T DE 60224291T DE 60224291 D1 DE60224291 D1 DE 60224291D1
Authority
DE
Germany
Prior art keywords
expression
synthesis
antibodies
antibody expression
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60224291T
Other languages
English (en)
Other versions
DE60224291T2 (de
Inventor
Dana C Andersen
Laura C Simmons
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of DE60224291D1 publication Critical patent/DE60224291D1/de
Publication of DE60224291T2 publication Critical patent/DE60224291T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2845Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/54F(ab')2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60224291T 2001-08-27 2002-08-26 System zur antikörperexpression und- synthese Expired - Lifetime DE60224291T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US31520901P 2001-08-27 2001-08-27
US315209P 2001-08-27
PCT/US2002/027220 WO2003018771A2 (en) 2001-08-27 2002-08-26 A system for antibody expression and assembly

Publications (2)

Publication Number Publication Date
DE60224291D1 true DE60224291D1 (de) 2008-02-07
DE60224291T2 DE60224291T2 (de) 2008-12-11

Family

ID=23223369

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60224291T Expired - Lifetime DE60224291T2 (de) 2001-08-27 2002-08-26 System zur antikörperexpression und- synthese

Country Status (11)

Country Link
US (6) US20030077739A1 (de)
EP (1) EP1427744B1 (de)
JP (1) JP4461210B2 (de)
KR (1) KR100968664B1 (de)
CN (1) CN100513414C (de)
AT (1) ATE382053T1 (de)
CA (1) CA2454731C (de)
DE (1) DE60224291T2 (de)
MX (1) MXPA04001566A (de)
NZ (1) NZ530852A (de)
WO (1) WO2003018771A2 (de)

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EP3753948A1 (de) 2014-11-05 2020-12-23 Genentech, Inc. Verfahren zur herstellung von zweikettigen proteinen in bakterien
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US20220042035A1 (en) * 2018-02-14 2022-02-10 Generation Bio Co. Non-viral dna vectors and uses thereof for antibody and fusion protein production
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Also Published As

Publication number Publication date
KR100968664B1 (ko) 2010-07-06
US20060246542A1 (en) 2006-11-02
ATE382053T1 (de) 2008-01-15
EP1427744B1 (de) 2007-12-26
CA2454731A1 (en) 2003-03-06
US20110244517A1 (en) 2011-10-06
CN100513414C (zh) 2009-07-15
WO2003018771A2 (en) 2003-03-06
DE60224291T2 (de) 2008-12-11
EP1427744A2 (de) 2004-06-16
KR20040031011A (ko) 2004-04-09
US20070015244A1 (en) 2007-01-18
CN1549821A (zh) 2004-11-24
US20070224664A1 (en) 2007-09-27
US20140120580A1 (en) 2014-05-01
WO2003018771A3 (en) 2004-03-11
NZ530852A (en) 2006-11-30
US9688775B2 (en) 2017-06-27
CA2454731C (en) 2010-11-02
MXPA04001566A (es) 2004-05-17
JP4461210B2 (ja) 2010-05-12
US20030077739A1 (en) 2003-04-24
JP2005517385A (ja) 2005-06-16
EP1427744A4 (de) 2005-12-07

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