DE60214905D1 - Eintopfverfahren zur herstellung von artesunsäure aus artemisinin - Google Patents
Eintopfverfahren zur herstellung von artesunsäure aus artemisininInfo
- Publication number
- DE60214905D1 DE60214905D1 DE60214905T DE60214905T DE60214905D1 DE 60214905 D1 DE60214905 D1 DE 60214905D1 DE 60214905 T DE60214905 T DE 60214905T DE 60214905 T DE60214905 T DE 60214905T DE 60214905 D1 DE60214905 D1 DE 60214905D1
- Authority
- DE
- Germany
- Prior art keywords
- eintopf
- artemisinin
- properties
- production
- artesunic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229960004191 artemisinin Drugs 0.000 title 1
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 title 1
- 229930101531 artemisinin Natural products 0.000 title 1
- 229960004991 artesunate Drugs 0.000 title 1
- FIHJKUPKCHIPAT-AHIGJZGOSA-N artesunate Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2O[C@@H](OC(=O)CCC(O)=O)[C@@H]4C FIHJKUPKCHIPAT-AHIGJZGOSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IB2002/005063 WO2004050661A1 (en) | 2002-12-02 | 2002-12-02 | Single pot conversion of artemisinin to artesunic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60214905D1 true DE60214905D1 (de) | 2006-11-02 |
Family
ID=32448800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60214905T Expired - Lifetime DE60214905D1 (de) | 2002-12-02 | 2002-12-02 | Eintopfverfahren zur herstellung von artesunsäure aus artemisinin |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1569940B1 (de) |
| JP (1) | JP4408812B2 (de) |
| CN (1) | CN1314687C (de) |
| AU (1) | AU2002347535A1 (de) |
| CA (1) | CA2508333C (de) |
| DE (1) | DE60214905D1 (de) |
| WO (1) | WO2004050661A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008087667A1 (en) * | 2007-01-19 | 2008-07-24 | Almet Corporation | Preparative process for artesunate from artemisinin |
| WO2012017004A1 (en) * | 2010-08-03 | 2012-02-09 | Dafra Pharma N.V. | Novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties |
| CN103214496A (zh) * | 2013-03-15 | 2013-07-24 | 彭学东 | 一种双氢青蒿素的简单快速制备工艺 |
-
2002
- 2002-12-02 WO PCT/IB2002/005063 patent/WO2004050661A1/en active IP Right Grant
- 2002-12-02 JP JP2004556564A patent/JP4408812B2/ja not_active Expired - Fee Related
- 2002-12-02 EP EP02783466A patent/EP1569940B1/de not_active Expired - Lifetime
- 2002-12-02 CN CNB028301471A patent/CN1314687C/zh not_active Expired - Fee Related
- 2002-12-02 DE DE60214905T patent/DE60214905D1/de not_active Expired - Lifetime
- 2002-12-02 CA CA2508333A patent/CA2508333C/en not_active Expired - Fee Related
- 2002-12-02 AU AU2002347535A patent/AU2002347535A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1569940A1 (de) | 2005-09-07 |
| WO2004050661A1 (en) | 2004-06-17 |
| CA2508333C (en) | 2010-07-20 |
| EP1569940B1 (de) | 2006-09-20 |
| CN1720247A (zh) | 2006-01-11 |
| CN1314687C (zh) | 2007-05-09 |
| CA2508333A1 (en) | 2004-06-17 |
| AU2002347535A1 (en) | 2004-06-23 |
| JP4408812B2 (ja) | 2010-02-03 |
| JP2006516118A (ja) | 2006-06-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8332 | No legal effect for de |