[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DE602006012650D1 - Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung - Google Patents

Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung

Info

Publication number
DE602006012650D1
DE602006012650D1 DE602006012650T DE602006012650T DE602006012650D1 DE 602006012650 D1 DE602006012650 D1 DE 602006012650D1 DE 602006012650 T DE602006012650 T DE 602006012650T DE 602006012650 T DE602006012650 T DE 602006012650T DE 602006012650 D1 DE602006012650 D1 DE 602006012650D1
Authority
DE
Germany
Prior art keywords
benzisoxazolpiperidin
compounds
application
compositions
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006012650T
Other languages
English (en)
Inventor
Daniel Coughlin
James F White
Kazumi Shiosaki
David G Hangauer
Michael Solomon
Dale M Edgar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hypnion Inc
Original Assignee
Hypnion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hypnion Inc filed Critical Hypnion Inc
Publication of DE602006012650D1 publication Critical patent/DE602006012650D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE602006012650T 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung Active DE602006012650D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US67520205P 2005-04-26 2005-04-26
PCT/US2006/016057 WO2006116614A1 (en) 2005-04-26 2006-04-26 Benzisoxazole piperidine compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
DE602006012650D1 true DE602006012650D1 (de) 2010-04-15

Family

ID=36754209

Family Applications (2)

Application Number Title Priority Date Filing Date
DE602006013115T Active DE602006013115D1 (de) 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
DE602006012650T Active DE602006012650D1 (de) 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE602006013115T Active DE602006013115D1 (de) 2005-04-26 2006-04-26 Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung

Country Status (15)

Country Link
US (3) US8129410B2 (de)
EP (2) EP1877390B1 (de)
JP (2) JP5049267B2 (de)
CN (1) CN101208314B (de)
AT (2) ATE461925T1 (de)
AU (1) AU2006239302B2 (de)
CA (2) CA2606473C (de)
CY (1) CY1110026T1 (de)
DE (2) DE602006013115D1 (de)
DK (1) DK1877390T3 (de)
ES (2) ES2341127T3 (de)
MX (1) MX2007013352A (de)
PL (1) PL1877390T3 (de)
PT (1) PT1877390E (de)
WO (1) WO2006116614A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS20060035A (en) 2003-07-22 2008-08-07 Arena Pharmaceuticals Inc., Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto
SA05260357B1 (ar) 2004-11-19 2008-09-08 ارينا فارماسيتو تيكالز ، أنك مشتقات 3_فينيل_بيرازول كمعدلات لمستقبل سيروتينين 5_ht2a مفيدة في علاج الاضطرابات المتعلقه به
WO2006116614A1 (en) * 2005-04-26 2006-11-02 Hypnion, Inc. Benzisoxazole piperidine compounds and methods of use thereof
US8148417B2 (en) 2006-05-18 2012-04-03 Arena Pharmaceuticals, Inc. Primary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
USRE45337E1 (en) 2006-05-18 2015-01-13 Arena Pharmaceuticals, Inc. Ethers, secondary amines and derivatives thereof as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
SG171681A1 (en) 2006-05-18 2011-06-29 Arena Pharm Inc Crystalline forms and processes for the preparation of phenyl-pyrazoles useful as modulators of the 5-ht2a serotonin receptor
US7762006B2 (en) * 2006-06-14 2010-07-27 Siestamed, Technologies Medical equipment drying device
TWI415845B (zh) 2006-10-03 2013-11-21 Arena Pharm Inc 用於治療與５-ｈｔ2ａ血清素受體相關聯病症之作為５-ｈｔ2ａ血清素受體之調節劑的吡唑衍生物
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
KR20090128499A (ko) * 2007-03-19 2009-12-15 인슐린 메디컬 엘티디 약물 전달 장치
US9220837B2 (en) * 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US20100286467A1 (en) * 2007-03-19 2010-11-11 Benny Pesach Device for drug delivery and associated connections thereto
EP2190844B3 (de) 2007-08-15 2013-07-17 Arena Pharmaceuticals, Inc. Imidazo[1,2-a]pyridinderivate als modulatoren des 5-ht2a-serotoninrezeptors, die sich für die behandlung von damit in zusammenhang stehenden erkrankungen eignen
US8409133B2 (en) 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
WO2009123714A2 (en) 2008-04-02 2009-10-08 Arena Pharmaceuticals, Inc. Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor
WO2009126830A2 (en) * 2008-04-09 2009-10-15 Surmodics, Inc. Delivery of nucleic acid complexes from materials including negatively charged groups
SG176464A1 (en) 2008-05-09 2011-12-29 Agency Science Tech & Res Diagnosis and treatment of kawasaki disease
US9034911B2 (en) 2008-10-28 2015-05-19 Arena Pharmaceuticals, Inc. Composition of a 5-HT2A serotonin receptor modulator useful for the treatment of disorders related thereto
WO2010062321A1 (en) 2008-10-28 2010-06-03 Arena Pharmaceuticals, Inc. Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)-urea and crystalline forms related thereto
KR20110086132A (ko) 2008-11-07 2011-07-27 인슐린 메디컬 엘티디 약물 전달 장치 및 방법
WO2010074753A1 (en) 2008-12-23 2010-07-01 Map Pharmaceuticals, Inc. Inhalation devices and related methods for administration of sedative hypnotic compounds
US8980891B2 (en) 2009-12-18 2015-03-17 Arena Pharmaceuticals, Inc. Crystalline forms of certain 3-phenyl-pyrazole derivatives as modulators of the 5-HT2A serotonin receptor useful for the treatment of disorders related thereto
US8565107B2 (en) 2010-09-24 2013-10-22 Hand Held Products, Inc. Terminal configurable for use within an unknown regulatory domain
EP4119141A1 (de) 2015-06-12 2023-01-18 Axovant Sciences GmbH Nelotanserin zur prophylaxe und behandlung von schlafverhaltensstörungen in der rem-phase
WO2017011767A2 (en) 2015-07-15 2017-01-19 Axovant Sciences Ltd. Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease
WO2021132311A1 (ja) * 2019-12-24 2021-07-01 大日本住友製薬株式会社 脂肪族酸アミド誘導体

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3331541A (en) * 1965-06-07 1967-07-18 Bell & Howell Co Sprocketless projector
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
US5364866A (en) 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
FR2654104B1 (fr) 1989-11-07 1992-01-03 Adir Nouveaux derives du 1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
DK60593D0 (da) * 1993-05-26 1993-05-26 Novo Nordisk As Kemiske forbindelser, deres fremstilling og anvendelse
FR2742052B1 (fr) * 1995-12-12 1998-04-10 Esteve Labor Dr Utilisation des derives 1-(4-(4-aryl (ou heteroaryl)-1-piper azinyl)-buty)-1h-azole pour le traitement de la depression, des troubles obsessifs compulsifs, l'apnee du sommeil, les dysfonctions sexuelles, l'emese et le mal des transports
ZA9610738B (en) 1995-12-22 1997-06-24 Warner Lambert Co Subtype selective nmda receptor ligands and the use thereof
WO1997049698A1 (en) 1996-06-21 1997-12-31 Glaxo Group Limited Piperidine acetic acid derivatives and their use in the treatment of thrombotic disorders
CN1129578C (zh) * 1997-12-25 2003-12-03 明治制果株式会社 四氢苯并吲哚衍生物
US6331541B1 (en) 1998-12-18 2001-12-18 Soo S. Ko N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
US6605623B1 (en) 1998-12-18 2003-08-12 Bristol-Myers Squibb Pharma Co. N-ureidoalkyl-piperidines as modulators of chemokine receptor activity
ES2165274B1 (es) * 1999-06-04 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
DK1632483T3 (da) 2001-02-16 2009-03-02 Aventis Pharma Inc Heterocykliske, substituerede carbonylderivater og deres anvendelse som dopamin-D3-receptorligander
GB0117577D0 (en) * 2001-02-16 2001-09-12 Aventis Pharm Prod Inc Novel heterocyclic substituted carbonyl derivatives and their use as dopamine D receptor ligands
US7355042B2 (en) * 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
WO2006116614A1 (en) * 2005-04-26 2006-11-02 Hypnion, Inc. Benzisoxazole piperidine compounds and methods of use thereof

Also Published As

Publication number Publication date
DE602006013115D1 (de) 2010-05-06
JP2008539267A (ja) 2008-11-13
WO2006116614A1 (en) 2006-11-02
CA2606471C (en) 2014-02-11
PT1877390E (pt) 2010-05-31
DK1877390T3 (da) 2010-05-31
CA2606473A1 (en) 2006-11-02
US7494998B2 (en) 2009-02-24
US20090163514A1 (en) 2009-06-25
CA2606473C (en) 2013-08-13
US8129410B2 (en) 2012-03-06
PL1877390T3 (pl) 2010-08-31
CA2606471A1 (en) 2006-11-02
JP5049267B2 (ja) 2012-10-17
CY1110026T1 (el) 2015-01-14
ES2340066T3 (es) 2010-05-28
JP2008539268A (ja) 2008-11-13
AU2006239302B2 (en) 2011-07-07
US8088778B2 (en) 2012-01-03
EP1877405A1 (de) 2008-01-16
CN101208314B (zh) 2010-12-08
EP1877390A1 (de) 2008-01-16
AU2006239302A1 (en) 2006-11-02
ES2341127T3 (es) 2010-06-15
ATE461925T1 (de) 2010-04-15
EP1877405B1 (de) 2010-03-03
CN101208314A (zh) 2008-06-25
MX2007013352A (es) 2008-03-26
US20080214539A1 (en) 2008-09-04
EP1877390B1 (de) 2010-03-24
ATE459621T1 (de) 2010-03-15
US20070004752A1 (en) 2007-01-04

Similar Documents

Publication Publication Date Title
DE602006013115D1 (de) Benzisoxazolpiperidinverbindungen und verfahren zu deren anwendung
DE602007005256D1 (de) Verbindungen und verfahren zur modulierung von fx-rezeptoren
ATE548374T1 (de) 2'-fluor-2'-desoxytetrahydrouridine als cytidindeaminaseinhibitoren
CY1113386T1 (el) Αναστολεις πρωτεασωματος
DK1879573T3 (da) Modulatorer af indolamin 2,3-dioxygenase og fremgangsmåder til anvendelse deraf
DE602006017980D1 (de) 3,4-substituierte pyrrolidin-derivate zur behandlung von hypertonie
DE602006021318D1 (de) Insektizidzusammensetzungen und verfahren zur hersn
NO20090157L (no) Tienpyrimidiner anvendelige som modulatorer av ionekanaler
DE602006015182D1 (de) Zusammensetzung und verfahren zur kontrolle von insekten
DE602005026984D1 (de) Chinolin-derivate zur behandlung von latenter tuberkulose
DE602006010400D1 (de) Olanzapin-analoga und verfahren zu ihrer verwendung
ATE407985T1 (de) Tinte, tintenset und aufzeichnungsmethode
DE602006005437D1 (de) Verfahren und Vorrichtung zum Herstellung von Bauteilen
ATE413875T1 (de) Zusammensetzungen enthaltend levetiracetam und verfahren zu deren herstellung.
ATE473744T1 (de) Modifizierte pyrimidin-glucocorticoid-rezeptor- modulatoren
SG136953A1 (en) Aqueous cleaning composition and method for using same
DE602005004280D1 (de) Verfahren zum ziehen von sic-einkristallen und sic-einkristall
ATE504585T1 (de) Heterocyclische verbindungen, zusammensetzungen damit und verfahren zu ihrer anwendung
ATE439831T1 (de) Stabile kristalline form von bifeprunoxmesylat, dosierungsformen davon und verfahren zu deren verwendung
DE602006019754D1 (de) Verfahren und zusammensetzung, die immunomodulatorische verbindungen zur behandlung von mit niedrigen plasmaleptin-spiegeln in zusammenhang stehenden störungen verwenden
DE602005024599D1 (de) Verbindungen modulierende thrombopoietinaktivität und verfahren
ATE512967T1 (de) Als kinaseinhibitoren geeignete pyrrolotriazinverbindungen
NO20075140L (no) Fremgangsmater og preparater for modulering av vaskulaer integritet
ATE495752T1 (de) Verfahren und zusammensetzungen zur notfallbedingten verhütung mithilfe von endothelin-rezeptor-antagonisten
ATE525382T1 (de) Azazucker-derivate, heparanase-hemmer, verfahren zu deren herstellung, zusammensetzungen damit und verwendung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN