DE602006014097D1 - Cgrp-rezeptorantagonisten - Google Patents

Cgrp-rezeptorantagonisten

Info

Publication number: DE602006014097D1
Authority: DE; Germany
Prior art keywords: receptor antagonists; cgrp receptor; cgrp; compounds; diseases
Prior art date: 2005-01-18
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Active

Application number

DE602006014097T

Other languages

English (en)

Inventor

Christopher S Burgey

Theresa M Williams

Zhengwu J Deng

Craig A Stump

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck Sharp and Dohme LLC

Original Assignee

Merck Sharp and Dohme LLC

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-01-18

Filing date

2006-01-13

Publication date

2010-06-17

2006-01-13 Application filed by Merck Sharp and Dohme LLC filed Critical Merck Sharp and Dohme LLC

2010-06-17 Publication of DE602006014097D1 publication Critical patent/DE602006014097D1/de

Status Active legal-status Critical Current

2026-01-14 Anticipated expiration legal-status Critical

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pain & Pain Management (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Plural Heterocyclic Compounds (AREA)

DE602006014097T 2005-01-18 2006-01-13 Cgrp-rezeptorantagonisten Active DE602006014097D1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US64465005P	2005-01-18	2005-01-18
PCT/US2006/001252 WO2006078554A2 (en)	2005-01-18	2006-01-13	Cgrp receptor antagonists

Publications (1)

Publication Number	Publication Date
DE602006014097D1 true DE602006014097D1 (de)	2010-06-17

Family

ID=36692743

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE602006014097T Active DE602006014097D1 (de)	2005-01-18	2006-01-13	Cgrp-rezeptorantagonisten

Country Status (9)

Country	Link
US (1)	US7632832B2 (de)
EP (1)	EP1856100B1 (de)
JP (1)	JP2008526984A (de)
CN (1)	CN101103020B (de)
AT (1)	ATE466853T1 (de)
AU (1)	AU2006206718B2 (de)
CA (1)	CA2594940A1 (de)
DE (1)	DE602006014097D1 (de)
WO (1)	WO2006078554A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2005294448B2 (en) *	2004-10-07	2011-07-14	Merck Sharp & Dohme Corp.	CGRP receptor antagonists
EP2013213B1 (de)	2006-05-02	2011-07-27	Bristol-Myers Squibb Company	Verbindungen mit eingeschränkter konformation als cgrp rezeptor antagonisten.
US7470680B2 (en)	2006-05-03	2008-12-30	Bristol-Myers Squibb Company	Constrained compounds as CGRP-receptor antagonists
EP2024358B1 (de) *	2006-05-09	2014-11-05	Merck Sharp & Dohme Corp.	Substituierte spirocyclische cgrp-rezeptorantagonisten
KR20150081370A (ko)	2006-07-10	2015-07-13	파이온 유케이 리미티드	속효형 벤조디아제핀 염 및 이의 중합체 형태
EP2305647A1 (de) *	2009-09-18	2011-04-06	PAION UK Limited	Verfahren zur Herstellung von 3-[(4S)-8-brom-1-methyl-6-(2-pyridinyl)-4 H-imidazo[1,2-a][1,4]benzodiazepin-4-yl]propionsäuremethylester oder das Benzensulfonatsalz davon und in diesem Prozess nützliche Verbindungen
EP2450039A1 (de)	2010-11-08	2012-05-09	PAION UK Ltd.	Dosierschema zur Sedierung mit CNS 7056 (Remimazolam)
CN104411301B (zh) *	2012-04-18	2018-02-06	康特拉医药公司	适于改善运动障碍治疗的口服药物配方
AR094963A1 (es)	2013-03-04	2015-09-09	Ono Pharmaceutical Co	Reacción de oxidación excelente en el índice de conversión
WO2018011181A1 (en)	2016-07-11	2018-01-18	Contera Pharma Aps	Pulsatile drug delivery system for treating morning akinesia
EP3366286A1 (de)	2017-02-22	2018-08-29	Johannes Keller	Verbindungen zur behandlung von sepsis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6211499A (en)	1998-09-30	2000-04-17	Merck & Co., Inc.	Benzimidazolinyl piperidines as cgrp ligands
JP4705908B2 (ja)	2003-04-15	2011-06-22	メルク・シャープ・エンド・ドーム・コーポレイション	Ｃｇｒｐ受容体拮抗薬
AU2004252150B2 (en)	2003-06-26	2008-11-20	Merck Sharp & Dohme Corp.	Benzodiazepine CGRP receptor antagonists

2006
- 2006-01-13 DE DE602006014097T patent/DE602006014097D1/de active Active
- 2006-01-13 JP JP2007551403A patent/JP2008526984A/ja not_active Withdrawn
- 2006-01-13 AT AT06718339T patent/ATE466853T1/de not_active IP Right Cessation
- 2006-01-13 CN CN2006800024029A patent/CN101103020B/zh not_active Expired - Fee Related
- 2006-01-13 EP EP06718339A patent/EP1856100B1/de not_active Not-in-force
- 2006-01-13 US US11/795,678 patent/US7632832B2/en active Active
- 2006-01-13 CA CA002594940A patent/CA2594940A1/en not_active Abandoned
- 2006-01-13 AU AU2006206718A patent/AU2006206718B2/en not_active Ceased
- 2006-01-13 WO PCT/US2006/001252 patent/WO2006078554A2/en active Application Filing

Also Published As

Publication number	Publication date
AU2006206718A1 (en)	2006-07-27
US7632832B2 (en)	2009-12-15
WO2006078554A3 (en)	2007-04-05
CA2594940A1 (en)	2006-07-27
CN101103020B (zh)	2011-04-27
ATE466853T1 (de)	2010-05-15
EP1856100A4 (de)	2009-04-15
CN101103020A (zh)	2008-01-09
JP2008526984A (ja)	2008-07-24
WO2006078554A2 (en)	2006-07-27
EP1856100A2 (de)	2007-11-21
AU2006206718B2 (en)	2011-06-02
US20080125413A1 (en)	2008-05-29
EP1856100B1 (de)	2010-05-05

Publication	Publication Date	Title
ATE537170T1 (de)	2011-12-15	Cgrp-rezeptorantagonisten
NO20072435L (no)	2007-07-12	CGRP-reseptorantagonister
DE602005020655D1 (de)	2010-05-27	Carboxamid-spirolactam-cgrp-rezeptor-antagonisten
TW200505903A (en)	2005-02-16	CGRP receptor antagonists
ATE466860T1 (de)	2010-05-15	Cgrp-rezeptorantagonisten
DE602004013563D1 (de)	2008-06-19	Rantagonisten
ATE466853T1 (de)	2010-05-15	Cgrp-rezeptorantagonisten
ATE516803T1 (de)	2011-08-15	Aryl-spirohydantoin-cgrp-rezeptor-antagonisten
ATE464305T1 (de)	2010-04-15	Bicyclische anilidspirolactame als antagonisten des cgrp-rezeptors
ATE535514T1 (de)	2011-12-15	Carboxamid-spirohydantoin-cgrp-rezeptor- antagonisten
ATE556060T1 (de)	2012-05-15	Monocyclische anilidspirohydantoine als cgrp- rezeptorantagonisten
ATE509019T1 (de)	2011-05-15	Benzodiazepinspirohydantoine als cgrp- rezeptorantagonisten
WO2005013894A3 (en)	2006-03-02	Benzodiazepine cgrp receptor antagonists
WO2005000807A3 (en)	2006-01-05	Benzodiazepine cgrp receptor antagonists
WO2007016087A3 (en)	2007-06-21	Heterocyclic benzodiazepine cgrp receptor antagonists
ATE537153T1 (de)	2011-12-15	Arylspirolactamverbindungen als antagonisten des cgrp-rezeptors
ATE463245T1 (de)	2010-04-15	Tricyclische anilid-spirohydantoin-cgrp- rezeptorantagonisten
ATE503755T1 (de)	2011-04-15	Cgrp-rezeptorantagonisten
ATE518852T1 (de)	2011-08-15	Tricyclische anilid-spirohydantoin-cgrp- rezeptorantagonisten
WO2006041830A3 (en)	2006-06-01	Cgrp receptor antagonists
ATE507880T1 (de)	2011-05-15	Cgrp-rezeptorantagonisten

Legal Events

Date	Code	Title	Description
2011-05-26	8364	No opposition during term of opposition
2013-02-07	R081	Change of applicant/patentee	Ref document number: 1856100 Country of ref document: EP Owner name: SCHERING CORPORATION, US Free format text: FORMER OWNER: MERCK SHARP & DOHME CORP., RAHWAY, US Effective date: 20121213
2013-02-07	R082	Change of representative	Ref document number: 1856100 Country of ref document: EP Representative=s name: ABITZ & PARTNER, DE Effective date: 20121213

Date

Code

Title

Description

2011-05-26

8364

No opposition during term of opposition

2013-02-07

R081

Change of applicant/patentee

Ref document number: 1856100

Country of ref document: EP

Owner name: SCHERING CORPORATION, US

Free format text: FORMER OWNER: MERCK SHARP & DOHME CORP., RAHWAY, US

Effective date: 20121213