[go: up one dir, main page]
More Web Proxy on the site http://driver.im/

DE602005024012D1 - Lösungsmittelfreies amorphes rapamycin - Google Patents

Lösungsmittelfreies amorphes rapamycin

Info

Publication number
DE602005024012D1
DE602005024012D1 DE602005024012T DE602005024012T DE602005024012D1 DE 602005024012 D1 DE602005024012 D1 DE 602005024012D1 DE 602005024012 T DE602005024012 T DE 602005024012T DE 602005024012 T DE602005024012 T DE 602005024012T DE 602005024012 D1 DE602005024012 D1 DE 602005024012D1
Authority
DE
Germany
Prior art keywords
free
solvent
amorphes
rapamycin
therapeutic agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005024012T
Other languages
English (en)
Inventor
Cynthia A Maryanoff
Karel Six
Roger Vandecruys
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cordis Corp
Original Assignee
Cordis Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cordis Corp filed Critical Cordis Corp
Publication of DE602005024012D1 publication Critical patent/DE602005024012D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE602005024012T 2004-08-27 2005-08-24 Lösungsmittelfreies amorphes rapamycin Active DE602005024012D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60532404P 2004-08-27 2004-08-27
PCT/US2005/030606 WO2006026531A1 (en) 2004-08-27 2005-08-24 Solvent free amorphous rapamycin

Publications (1)

Publication Number Publication Date
DE602005024012D1 true DE602005024012D1 (de) 2010-11-18

Family

ID=35539393

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005024012T Active DE602005024012D1 (de) 2004-08-27 2005-08-24 Lösungsmittelfreies amorphes rapamycin

Country Status (7)

Country Link
US (2) US7393952B2 (de)
EP (1) EP1781672B1 (de)
JP (1) JP5117190B2 (de)
AT (1) ATE483716T1 (de)
CA (1) CA2578245C (de)
DE (1) DE602005024012D1 (de)
WO (1) WO2006026531A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8715771B2 (en) * 2003-02-26 2014-05-06 Abbott Cardiovascular Systems Inc. Coated stent and method of making the same
US7255891B1 (en) * 2003-02-26 2007-08-14 Advanced Cardiovascular Systems, Inc. Method for coating implantable medical devices
US8663639B2 (en) 2005-02-09 2014-03-04 Santen Pharmaceutical Co., Ltd. Formulations for treating ocular diseases and conditions
PL1848431T3 (pl) 2005-02-09 2016-08-31 Santen Pharmaceutical Co Ltd Ciekłe formulacje do leczenia chorób lub stanów
EP2001438A2 (de) 2006-02-09 2008-12-17 Macusight, Inc. Stabile formulierungen sowie verfahren zu ihrer herstellung und verwendung
BRPI0709016A2 (pt) 2006-03-23 2011-06-21 Macusight Inc formulações e métodos para doenças ou condições relacionadas com a permeabilidade vascular
US20090011117A1 (en) * 2007-07-03 2009-01-08 Endotronix, Inc. Methods for texturing a surface of an endovascular implant
US9533078B2 (en) 2008-06-25 2017-01-03 Boston Scientific Scimed, Inc. Medical devices containing therapeutic agents
IT1400977B1 (it) 2010-07-01 2013-07-05 Euticals Spa Nuovi complessi di inclusione farmaceutici, solidi, solubili in acqua e le loro soluzioni acquose per uso orale, oftalmico, topico o parenterale, contenenti un macrolide ed alcune ciclodestrine.
DK2948134T3 (da) 2013-01-24 2020-06-02 Palvella Therapeutics Inc Sammensætninger til transdermal indgivelse af mtor-inhibitorer
JP6472155B2 (ja) * 2013-04-01 2019-02-20 テルモ株式会社 ステントおよびステントデリバリーシステム
WO2015181826A1 (en) 2014-05-27 2015-12-03 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Crystalline coating and release of bioactive agents
EP4226868A1 (de) 2015-09-15 2023-08-16 Savage Medical, Inc. Vorrichtungen und verfahren zur verankerung einer schleuse in einer gewebehöhle
WO2018129364A1 (en) 2017-01-06 2018-07-12 Palvella Therapeutics Llc Anhydrous compositions of mtor inhibitors and methods of use
CN108129490B (zh) * 2017-12-11 2020-12-01 成都海创药业有限公司 一种制备依维莫司无定形固体的方法
US11000513B2 (en) 2018-07-02 2021-05-11 Palvella Therapeutics, Inc. Anhydrous compositions of mTOR inhibitors and methods of use

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA737247B (en) * 1972-09-29 1975-04-30 Ayerst Mckenna & Harrison Rapamycin and process of preparation
GB9221220D0 (en) * 1992-10-09 1992-11-25 Sandoz Ag Organic componds
FR2736550B1 (fr) 1995-07-14 1998-07-24 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
US6384213B1 (en) 1998-10-23 2002-05-07 Ranbaxy Laboratories Limited Process for preparing a pure, pharmacopoeial grade amorphous form of cefuroxime axetil
WO2002057228A1 (en) 2001-01-17 2002-07-25 Biocon India Limited Atorvastatin calcium
EP1500401A4 (de) * 2002-04-22 2009-12-23 Res Found Itsuu Lab Arzneimittel zur behandlung von gefässerkrankungen
DE10244847A1 (de) 2002-09-20 2004-04-01 Ulrich Prof. Dr. Speck Medizinische Vorrichtung zur Arzneimittelabgabe
CA2499594A1 (en) * 2002-09-20 2004-04-01 Conor Medsystems, Inc. Expandable medical device with openings for delivery of multiple beneficial agents
US20040093064A1 (en) * 2002-11-12 2004-05-13 Gjalt Bosma Drug eluting stent graft combination
CN1829514A (zh) 2003-07-25 2006-09-06 惠氏公司 Cci－779冻干制剂
CN1874771A (zh) 2003-09-03 2006-12-06 惠氏公司 3－羟基－2－(羟甲基)－2－甲基丙酸的非晶态雷帕霉素42－酯及其包含相同化合物的药用组合物

Also Published As

Publication number Publication date
US20060128739A1 (en) 2006-06-15
WO2006026531A1 (en) 2006-03-09
ATE483716T1 (de) 2010-10-15
US20080227982A1 (en) 2008-09-18
EP1781672B1 (de) 2010-10-06
CA2578245C (en) 2013-10-29
CA2578245A1 (en) 2006-03-09
JP2008511642A (ja) 2008-04-17
JP5117190B2 (ja) 2013-01-09
EP1781672A1 (de) 2007-05-09
US7393952B2 (en) 2008-07-01

Similar Documents

Publication Publication Date Title
DE602005024012D1 (de) Lösungsmittelfreies amorphes rapamycin
NO20073065L (no) Injiserbare nanopartikulaere olanzapinformuleringer
CR8744A (es) Compuestos terapeuticos
NO20083002L (no) Fremgangsmate for anvendelse av CD40-bindende forbindelser
TW200740815A (en) P38 MAP kinase inhibitors and methods for using the same
MY148491A (en) FUSED BICYCLIC mTOR INHIBITORS
IL177483A0 (en) Means for transdermal administration of nicotine
WO2007087395A3 (en) UNSATURATED mTOR INHIBITORS
TW200740776A (en) N-phenylbenzotriazolyl c-kit inhibitors
TN2012000152A1 (en) Spiropiperidine compounds and pharmaceutical use thereof for treating diabetes
UA84712C2 (en) N-substituted pyrazolyl-amidyl-benzimidazolyl c-kit inhibitors
TW200519111A (en) N3-substituted imidazopyridine C-KIT inhibitors
CY1124331T1 (el) Αυξημενη βιοδιαθεσιμοτητα δραστικης ουσιας σε θεραπεια ναλτρεξονης
MX2012002528A (es) Agente terapeutico para trastornos del estado de animo.
BRPI0415164A (pt) dispositivo para administrar uma composição bioterapêutica, composição bioterapêutica, método de preparação de uma composição bioterapêutica, método de tratamento, e dispensador
MX2010007546A (es) Pirimidil ciclopentanos hidroxilados en forma de inhibidores de akt proteína quinasa.
GB0416508D0 (en) Therapeutic agents
NO20072832L (no) Smertestillende middel
MX2010001303A (es) Compuestos terapeuticos.
WO2009076220A1 (en) Methods for delivering sirna via iontophoresis
NO20092496L (no) Ny terapeutisk anvendelse for behandling av leukemi
TW200631584A (en) A medicament related to mirtazapine for the treatment of hot flush
MY140538A (en) Substituted n-acyl-2-aminothiazoles
TW200730150A (en) Methods for determining coating thickness of a prosthesis
NO20064410L (no) Fremgangsmate for fremstilling av tryptaseinhibitorer