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DE60143668D1 - Peptidinhibitoren gegen den eintritt von hiv in zellen - Google Patents

Peptidinhibitoren gegen den eintritt von hiv in zellen

Info

Publication number
DE60143668D1
DE60143668D1 DE60143668T DE60143668T DE60143668D1 DE 60143668 D1 DE60143668 D1 DE 60143668D1 DE 60143668 T DE60143668 T DE 60143668T DE 60143668 T DE60143668 T DE 60143668T DE 60143668 D1 DE60143668 D1 DE 60143668D1
Authority
DE
Germany
Prior art keywords
hiv
cells
peptidinhibitors
initiation
molecules
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60143668T
Other languages
English (en)
Inventor
Debra M Eckert
Tara R Suntoke
Peter S Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Whitehead Institute for Biomedical Research
Original Assignee
Whitehead Institute for Biomedical Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/668,072 external-priority patent/US6747126B1/en
Application filed by Whitehead Institute for Biomedical Research filed Critical Whitehead Institute for Biomedical Research
Application granted granted Critical
Publication of DE60143668D1 publication Critical patent/DE60143668D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
    • C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60143668T 2000-09-22 2001-09-21 Peptidinhibitoren gegen den eintritt von hiv in zellen Expired - Lifetime DE60143668D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/668,072 US6747126B1 (en) 1998-07-30 2000-09-22 Peptide inhibitors of HIV entry
PCT/US2001/029637 WO2002024735A2 (en) 2000-09-22 2001-09-21 Peptide inhibitors of hiv entry

Publications (1)

Publication Number Publication Date
DE60143668D1 true DE60143668D1 (de) 2011-01-27

Family

ID=24680888

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60143668T Expired - Lifetime DE60143668D1 (de) 2000-09-22 2001-09-21 Peptidinhibitoren gegen den eintritt von hiv in zellen

Country Status (7)

Country Link
EP (1) EP1353942B1 (de)
JP (1) JP5180422B2 (de)
AT (1) ATE491719T1 (de)
AU (3) AU2001292944B2 (de)
CA (1) CA2423004C (de)
DE (1) DE60143668D1 (de)
WO (1) WO2002024735A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747126B1 (en) 1998-07-30 2004-06-08 Whitehead Institute For Biomedical Research Peptide inhibitors of HIV entry
US7960504B2 (en) 1998-07-30 2011-06-14 Whitehead Institute For Biomedical Research Inhibitors of HIV membrane fusion
WO2001044286A2 (en) 1999-12-16 2001-06-21 Whitehead Institute For Biomedical Research Five-helix protein
EP1500662A3 (de) * 2003-05-19 2005-09-21 Cornell Research Foundation, Inc. Stabilisierende Peptide und Ihre Verwendung zur Herstellung von stabilisierten HIV-Inhibitoren
WO2004106364A1 (en) * 2003-08-05 2004-12-09 Cornell Research Foundation, Inc. Stabilizing peptides and their use in the preparation of stabilized hiv inhibitors
CA2544848C (en) * 2003-11-04 2015-12-29 The Administrators Of The Tulane Educational Fund Method of preventing virus: cell fusion by inhibiting the function of the fusion initiation region in rna viruses having class i membrane fusogenic envelope proteins
CA2567030C (en) * 2004-06-01 2015-10-06 Elisabetta Bianchi Stable peptide mimetic of hiv gp41 fusion intermediate
JP2008534640A (ja) * 2005-04-05 2008-08-28 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー タンパク質の機能部位またはエピトープの遮蔽方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20010099605A (ko) * 1998-07-30 2001-11-09 존 프랫 Ｈｉｖ 막융합 억제제
EP1149115A4 (de) * 1999-01-08 2005-11-02 Panacos Pharmaceuticals Inc Verfahren zum hervorrufen von breit wirksamen, neutralisierenden antikörpern, die gegen gp41 von hiv-1 gerichtet sind.
RU2143843C1 (ru) * 1999-04-28 2000-01-10 Обабков Анатолий Иванович Способ экспресс-диагностики физиологического состояния биологического объекта и устройство для его осуществления

Also Published As

Publication number Publication date
AU9294401A (en) 2002-04-02
EP1353942A2 (de) 2003-10-22
WO2002024735A3 (en) 2003-08-14
EP1353942B1 (de) 2010-12-15
JP2004509901A (ja) 2004-04-02
AU2005225063A1 (en) 2005-11-10
AU2001292944B2 (en) 2005-07-21
WO2002024735A2 (en) 2002-03-28
JP5180422B2 (ja) 2013-04-10
AU2005225063B2 (en) 2009-06-25
CA2423004C (en) 2012-09-11
CA2423004A1 (en) 2002-03-28
ATE491719T1 (de) 2011-01-15

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