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DE60136490D1 - Sn-38-lipidkomplexe und verfahren zu ihrer verwendung - Google Patents

Sn-38-lipidkomplexe und verfahren zu ihrer verwendung

Info

Publication number
DE60136490D1
DE60136490D1 DE60136490T DE60136490T DE60136490D1 DE 60136490 D1 DE60136490 D1 DE 60136490D1 DE 60136490 T DE60136490 T DE 60136490T DE 60136490 T DE60136490 T DE 60136490T DE 60136490 D1 DE60136490 D1 DE 60136490D1
Authority
DE
Germany
Prior art keywords
complexes
compositions
lipid complexes
present
cardiolipin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60136490T
Other languages
English (en)
Inventor
Imran Ahmad
Jia-Ai Allen Zhang
Aquilur Rahman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neopharm Inc
Original Assignee
Neopharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neopharm Inc filed Critical Neopharm Inc
Application granted granted Critical
Publication of DE60136490D1 publication Critical patent/DE60136490D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
    • A61K47/6911—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a liposome
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60136490T 2000-11-09 2001-11-09 Sn-38-lipidkomplexe und verfahren zu ihrer verwendung Expired - Lifetime DE60136490D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24730600P 2000-11-09 2000-11-09
PCT/US2001/043325 WO2002058622A2 (en) 2000-11-09 2001-11-09 Sn-38 lipid complexes and methods of use

Publications (1)

Publication Number Publication Date
DE60136490D1 true DE60136490D1 (de) 2008-12-18

Family

ID=22934406

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60136490T Expired - Lifetime DE60136490D1 (de) 2000-11-09 2001-11-09 Sn-38-lipidkomplexe und verfahren zu ihrer verwendung

Country Status (22)

Country Link
US (1) US7390502B2 (de)
EP (1) EP1355634B8 (de)
JP (1) JP4524071B2 (de)
KR (1) KR100869824B1 (de)
CN (1) CN1531424A (de)
AT (1) ATE413164T1 (de)
AU (1) AU2002246510B2 (de)
BG (1) BG107862A (de)
BR (1) BR0115260A (de)
CA (1) CA2427467C (de)
CZ (1) CZ20031515A3 (de)
DE (1) DE60136490D1 (de)
EA (1) EA006741B1 (de)
HU (1) HUP0302352A3 (de)
IL (1) IL155696A0 (de)
MX (1) MXPA03004095A (de)
NO (1) NO20032069L (de)
NZ (1) NZ525552A (de)
PL (1) PL363618A1 (de)
SK (1) SK7092003A3 (de)
WO (1) WO2002058622A2 (de)
ZA (1) ZA200303432B (de)

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JP6838004B2 (ja) 2015-06-11 2021-03-03 リセラ・コーポレイションＬｙｃｅｒａ Ｃｏｒｐｏｒａｔｉｏｎ ＲＯＲγのアゴニストとしての使用及び疾患の治療のためのアリールジヒドロ−２Ｈ−ベンゾ［ｂ］［１，４］オキサジンスルホンアミド及び関連化合物
CN110302171A (zh) * 2019-07-12 2019-10-08 山东大学 一种瘤内注射用sn-38-plga缓释微球及其制备方法和应用
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MXPA03004095A (es) 2004-09-10
ZA200303432B (en) 2004-08-05
EP1355634A2 (de) 2003-10-29
AU2002246510B2 (en) 2007-09-20
BR0115260A (pt) 2005-08-16
BG107862A (bg) 2004-06-30
NO20032069D0 (no) 2003-05-08
JP4524071B2 (ja) 2010-08-11
IL155696A0 (en) 2003-11-23
HUP0302352A3 (en) 2007-03-28
KR100869824B1 (ko) 2008-11-21
CA2427467A1 (en) 2002-08-01
PL363618A1 (en) 2004-11-29
EP1355634B8 (de) 2009-03-04
EP1355634A4 (de) 2005-07-06
US20030215492A1 (en) 2003-11-20
EA200300550A1 (ru) 2004-06-24
WO2002058622A2 (en) 2002-08-01
AU2002246510A2 (en) 2002-08-06
CN1531424A (zh) 2004-09-22
WO2002058622A3 (en) 2003-08-28
NO20032069L (no) 2003-07-02
SK7092003A3 (en) 2004-06-08
ATE413164T1 (de) 2008-11-15
KR20030072352A (ko) 2003-09-13
HUP0302352A2 (hu) 2003-11-28
NZ525552A (en) 2005-04-29
EA006741B1 (ru) 2006-04-28
EP1355634B1 (de) 2008-11-05
JP2004529086A (ja) 2004-09-24
US7390502B2 (en) 2008-06-24
CA2427467C (en) 2010-01-12
CZ20031515A3 (cs) 2003-09-17

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