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DE60128587D1 - Lactamverbindungen - Google Patents

Lactamverbindungen

Info

Publication number
DE60128587D1
DE60128587D1 DE60128587T DE60128587T DE60128587D1 DE 60128587 D1 DE60128587 D1 DE 60128587D1 DE 60128587 T DE60128587 T DE 60128587T DE 60128587 T DE60128587 T DE 60128587T DE 60128587 D1 DE60128587 D1 DE 60128587D1
Authority
DE
Germany
Prior art keywords
lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60128587T
Other languages
English (en)
Other versions
DE60128587T2 (de
Inventor
Thomas Mitchell Koenig
James Edmund Audia
David Mitchell
Stacey Leigh Mcdaniel
Lynne Ann Buccilli
Gary Lowell Engel
James Abraham Aikins
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE60128587D1 publication Critical patent/DE60128587D1/de
Application granted granted Critical
Publication of DE60128587T2 publication Critical patent/DE60128587T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
DE60128587T 2000-11-17 2001-11-02 Lactamverbindungen Expired - Lifetime DE60128587T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24965600P 2000-11-17 2000-11-17
US249656P 2000-11-17
PCT/US2001/027795 WO2002040451A2 (en) 2000-11-17 2001-11-02 Lactam compound

Publications (2)

Publication Number Publication Date
DE60128587D1 true DE60128587D1 (de) 2007-07-05
DE60128587T2 DE60128587T2 (de) 2008-01-31

Family

ID=22944436

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60128587T Expired - Lifetime DE60128587T2 (de) 2000-11-17 2001-11-02 Lactamverbindungen

Country Status (33)

Country Link
US (1) US20040248878A1 (de)
EP (1) EP1353910B1 (de)
JP (1) JP4116431B2 (de)
KR (1) KR20030045194A (de)
CN (2) CN100516047C (de)
AR (1) AR031356A1 (de)
AT (1) ATE362919T1 (de)
AU (2) AU2002224321B2 (de)
BR (1) BR0115424A (de)
CA (1) CA2425497C (de)
CY (1) CY1106682T1 (de)
CZ (1) CZ20031340A3 (de)
DE (1) DE60128587T2 (de)
DK (1) DK1353910T3 (de)
DZ (1) DZ3454A1 (de)
EA (1) EA006919B1 (de)
EC (1) ECSP034598A (de)
ES (1) ES2286162T3 (de)
HR (1) HRP20030385A2 (de)
HU (1) HUP0301862A3 (de)
IL (1) IL155275A0 (de)
MX (1) MXPA03004250A (de)
MY (1) MY141607A (de)
NO (1) NO325217B1 (de)
PE (1) PE20020798A1 (de)
PL (1) PL211018B1 (de)
PT (1) PT1353910E (de)
SK (1) SK287794B6 (de)
SV (1) SV2003000741A (de)
TW (1) TWI235151B (de)
UA (1) UA77165C2 (de)
WO (1) WO2002040451A2 (de)
ZA (1) ZA200303411B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA74849C2 (en) * 2000-11-17 2006-02-15 Lilly Co Eli Lactam
EP1572215B1 (de) 2002-12-20 2009-09-02 Glaxo Group Limited Benzo[d]azepinderivate für die behandlung von neurologischen krankheiten
MXPA05007485A (es) 2003-01-14 2006-01-30 Arena Pharm Inc Derivados de arilo y heteroarilo 1,2,3-trisubstituidos como moduladores del metabolismo y la profilaxis y tratamiento de trastornos relacionados con ello tales como diabetes e hiperglicemia.
ES2413705T3 (es) 2005-04-08 2013-07-17 Daiichi Sankyo Company, Limited Derivado de piridilmetilsulfona
WO2007088878A1 (ja) * 2006-01-31 2007-08-09 Api Corporation ベンゾアゼピノン類の製造方法
TW200920362A (en) 2007-09-11 2009-05-16 Daiichi Sankyo Co Ltd Alkylsulfone derivatives
FR2932800B1 (fr) * 2008-06-20 2015-02-20 Servier Lab Nouveau procede de synthese de la 7,8-dimethoxy-1,3-dihydro- 2h-3-benzazepin-2-one, et application a la synthese de l'ivabradine et de ses sels d'addition a un acide pharmaceutiquement acceptable
BR112013008100A2 (pt) 2010-09-22 2016-08-09 Arena Pharm Inc "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles."
KR101899014B1 (ko) 2012-01-06 2018-09-17 삼성전자주식회사 비엘디씨 모터의 제어 장치 및 그 방법
CN102690231B (zh) * 2012-04-11 2014-07-09 南京友杰医药科技有限公司 治疗阿尔茨海默病潜在药物司马西特的合成方法
EP2987496B1 (de) 2013-04-19 2018-08-08 National University Corporation Okayama University Behandlungsmittel für durch amyloidprotein induzierte kognitive störungen, therapeutikum gegen morbus alzheimer sowie behandlungsverfahren und pathologisches analyseverfahren im zusammenhang damit
US11007175B2 (en) 2015-01-06 2021-05-18 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
CN108349891B (zh) 2015-06-22 2022-04-05 艾尼纳制药公司 用于s1p1受体相关病症的化合物的结晶l-精氨酸盐
MX2019009841A (es) 2017-02-16 2020-01-30 Arena Pharm Inc Compuestos y metodos para el tratamiento de la colangitis biliar primaria.
JP2023520771A (ja) 2020-03-26 2023-05-19 シージェン インコーポレイテッド 多発性骨髄腫を処置する方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69739236D1 (de) * 1996-12-23 2009-03-12 Lilly Co Eli Cycloalkyl-, lactam-, lacton- und verwandte verbindungen als hemmer der beta-amyloidpeptidfreisetzung
JP2002518481A (ja) * 1998-06-22 2002-06-25 エラン ファーマシューティカルズ，インコーポレイテッド β−アミロイドペプチドの放出および／またはその合成を阻害するための化合物
JP2003513958A (ja) * 1999-11-09 2003-04-15 イーライ・リリー・アンド・カンパニー β−アミロイドペプチド放出および／またはその合成を阻害するために有用なβ−アミノ酸化合物

Also Published As

Publication number Publication date
MY141607A (en) 2010-05-31
JP2004521084A (ja) 2004-07-15
HUP0301862A2 (hu) 2003-09-29
PL360991A1 (en) 2004-09-20
NO325217B1 (no) 2008-02-25
DK1353910T3 (da) 2007-09-10
SK5432003A3 (en) 2004-09-08
PL211018B1 (pl) 2012-03-30
SK287794B6 (sk) 2011-10-04
TWI235151B (en) 2005-07-01
CA2425497A1 (en) 2002-05-23
WO2002040451A3 (en) 2003-08-28
ES2286162T3 (es) 2007-12-01
AR031356A1 (es) 2003-09-17
DZ3454A1 (fr) 2002-05-23
BR0115424A (pt) 2003-10-21
CA2425497C (en) 2010-08-17
ZA200303411B (en) 2004-08-02
SV2003000741A (es) 2003-01-13
HRP20030385A2 (en) 2003-08-31
EA200300579A1 (ru) 2003-12-25
EA006919B1 (ru) 2006-04-28
CN101624372A (zh) 2010-01-13
US20040248878A1 (en) 2004-12-09
DE60128587T2 (de) 2008-01-31
MXPA03004250A (es) 2003-09-22
KR20030045194A (ko) 2003-06-09
NO20032215D0 (no) 2003-05-15
IL155275A0 (en) 2003-11-23
EP1353910B1 (de) 2007-05-23
WO2002040451A2 (en) 2002-05-23
EP1353910A2 (de) 2003-10-22
AU2002224321B2 (en) 2006-10-19
PE20020798A1 (es) 2002-09-06
JP4116431B2 (ja) 2008-07-09
NO20032215L (no) 2003-07-16
CN100516047C (zh) 2009-07-22
PT1353910E (pt) 2007-08-20
CN1575282A (zh) 2005-02-02
UA77165C2 (en) 2006-11-15
HUP0301862A3 (en) 2007-09-28
AU2432102A (en) 2002-05-27
CZ20031340A3 (cs) 2004-06-16
CY1106682T1 (el) 2012-05-23
ATE362919T1 (de) 2007-06-15
ECSP034598A (es) 2003-06-25

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN