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DE60110256D1 - Verfahren zum konzentrieren von analyten in proben - Google Patents

Verfahren zum konzentrieren von analyten in proben

Info

Publication number
DE60110256D1
DE60110256D1 DE60110256T DE60110256T DE60110256D1 DE 60110256 D1 DE60110256 D1 DE 60110256D1 DE 60110256 T DE60110256 T DE 60110256T DE 60110256 T DE60110256 T DE 60110256T DE 60110256 D1 DE60110256 D1 DE 60110256D1
Authority
DE
Germany
Prior art keywords
container
analyte
sample
present
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60110256T
Other languages
English (en)
Other versions
DE60110256T2 (de
Inventor
Pierre Puget
Patrick Pouteau
Frederic Ginot
Patrice Caillat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biom Rieux SA Marcy L Etoile
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Biom Rieux SA Marcy L Etoile
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biom Rieux SA Marcy L Etoile, Commissariat a lEnergie Atomique CEA filed Critical Biom Rieux SA Marcy L Etoile
Publication of DE60110256D1 publication Critical patent/DE60110256D1/de
Application granted granted Critical
Publication of DE60110256T2 publication Critical patent/DE60110256T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0825Test strips
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502723Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical or biological applications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Fluid Mechanics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Sampling And Sample Adjustment (AREA)
DE60110256T 2000-11-29 2001-11-27 Verfahren zum konzentrieren von analyten in proben Expired - Lifetime DE60110256T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0015417 2000-11-29
FR0015417A FR2817343B1 (fr) 2000-11-29 2000-11-29 Procede et dispositifs de transport et de concentration d'un analyte present dans un echantillon
PCT/FR2001/003743 WO2002043865A1 (fr) 2000-11-29 2001-11-27 Procedes et dispositifs de transport et de concentration d'un analyte present dans un echantillon

Publications (2)

Publication Number Publication Date
DE60110256D1 true DE60110256D1 (de) 2005-05-25
DE60110256T2 DE60110256T2 (de) 2006-03-09

Family

ID=8857009

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60110256T Expired - Lifetime DE60110256T2 (de) 2000-11-29 2001-11-27 Verfahren zum konzentrieren von analyten in proben

Country Status (7)

Country Link
US (1) US7569398B2 (de)
EP (1) EP1343586B1 (de)
AT (1) ATE293494T1 (de)
AU (1) AU2002222057A1 (de)
DE (1) DE60110256T2 (de)
FR (1) FR2817343B1 (de)
WO (1) WO2002043865A1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078224B1 (en) * 1999-05-14 2006-07-18 Promega Corporation Cell concentration and lysate clearance using paramagnetic particles
US20060186055A1 (en) * 2003-07-16 2006-08-24 Toyo Boseki Kabushiki Kaisha Device for separation of biological components, and method of separation of biological components using the device
DE10354351B3 (de) * 2003-11-20 2005-06-16 november Aktiengesellschaft Gesellschaft für Molekulare Medizin Verfahren und Vorrichtung zur verbesserten Reinigung einer an paramagnetische Mikropartikel gebundenen Substanz
FR2863626B1 (fr) * 2003-12-15 2006-08-04 Commissariat Energie Atomique Procede et dispositif de division d'un echantillon biologique par effet magnetique
DE102004005193B4 (de) * 2004-02-02 2006-08-24 Medion Diagnostics Gmbh Vorrichtung zur Separation einzelner Partikel von Partikel-Agglutinationen
JP2006053090A (ja) * 2004-08-13 2006-02-23 Alps Electric Co Ltd 検査用プレートと、前記検査用プレートを用いた検査方法
US8623668B2 (en) * 2004-11-05 2014-01-07 Imec Method for transport of magnetic particles and devices therefor
US7502625B2 (en) * 2005-01-20 2009-03-10 Skyworks Solutions, Inc. Integrated multi-band transceiver for use in mobile communication device
JP2009500019A (ja) * 2005-07-01 2009-01-08 プロメガ・コーポレーション 生体分子の精製のための浮遊性粒子のネットワーク、及び生体分子の精製のための浮遊性粒子又は浮遊性粒子のネットワークの使用
DE102005039175A1 (de) * 2005-08-18 2007-02-22 Qiagen Gmbh Vorrichtung und Verfahren zum Abtrennen von magnetischen Partikeln aus einer Flüssigkeit
EP1963526A4 (de) 2005-12-09 2009-11-18 Promega Corp Nukleinsäurereinigung mittels bindungsmatrix
EP1979751A1 (de) 2006-01-25 2008-10-15 Koninklijke Philips Electronics N.V. Vorrichtung zur analyse von fluiden
CN101495868A (zh) * 2006-07-28 2009-07-29 博适公司 利用磁性颗粒进行受体结合试验的装置和方法
EP1939629A3 (de) * 2006-08-11 2011-03-09 Samsung Electronics Co., Ltd. Vorrichtung zur zentrifugalkraftbasierten Magnetpositionssteuerung sowie scheibenförmiges Mikrofluidiksystem
CA2691451C (en) 2007-06-21 2015-03-24 Sara H. Fan Instrument and receptacles for performing processes
EP2188059B1 (de) * 2007-08-24 2016-05-04 Advanced Liquid Logic, Inc. Kügelchenmanipulation bei einem tröpfchenbetätiger
US20100300978A1 (en) * 2007-09-19 2010-12-02 Agency For Science, Technology And Research Device, system and method for washing and isolating magnetic particles in a continous fluid flow
EP2072133A1 (de) * 2007-12-20 2009-06-24 Koninklijke Philips Electronics N.V. Mehrkammervorrichtung mit magnetischen Partikeln
US8470148B2 (en) * 2008-01-17 2013-06-25 Ge Healthcare Bio-Sciences Ab Method for sample application
US8222397B2 (en) * 2009-08-28 2012-07-17 Promega Corporation Methods of optimal purification of nucleic acids and kit for use in performing such methods
US8039613B2 (en) 2009-08-28 2011-10-18 Promega Corporation Methods of purifying a nucleic acid and formulation and kit for use in performing such methods
EP2583101B1 (de) 2010-06-17 2015-09-16 Koninklijke Philips N.V. Multi-epitop-test
JP6382699B2 (ja) * 2014-11-28 2018-08-29 株式会社東芝 マイクロ分析チップ
CN105424922B (zh) * 2015-12-09 2018-01-19 北京乐普医疗科技有限责任公司 基于磁珠包被抗体的微流控芯片及捕获心肌标志物的方法
ES2871925T3 (es) * 2019-03-19 2021-11-02 Ace Medical Tech Co Ltd Dispositivo para clasificar biopartículas utilizando una fuerza generada a partir de dielectroforesis inducida por luz y su método de funcionamiento

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5498392A (en) 1992-05-01 1996-03-12 Trustees Of The University Of Pennsylvania Mesoscale polynucleotide amplification device and method
WO1994026414A1 (en) 1993-05-17 1994-11-24 Syntex (U.S.A.) Inc. Reaction container for specific binding assays and method for its use
US5603760A (en) * 1995-09-18 1997-02-18 W. R. Grace & Co.-Conn. Cement admixture capable of inhibiting drying shrinkage and method of using same
US5863502A (en) * 1996-01-24 1999-01-26 Sarnoff Corporation Parallel reaction cassette and associated devices
US6074827A (en) * 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
ATE211258T1 (de) * 1996-09-04 2002-01-15 Scandinavian Micro Biodevices Mikrofliesssystem für die teilchenanalyse und trennung
FR2758884B1 (fr) * 1997-01-30 1999-04-02 Bio Merieux Procede pour isoler, notamment detecter ou quantifier un analyte dans un milieu
ATE469699T1 (de) * 1999-02-23 2010-06-15 Caliper Life Sciences Inc Manipulation von mikroteilchen in mikrofluiden systemen

Also Published As

Publication number Publication date
US20040023273A1 (en) 2004-02-05
FR2817343B1 (fr) 2003-05-09
US7569398B2 (en) 2009-08-04
WO2002043865A1 (fr) 2002-06-06
ATE293494T1 (de) 2005-05-15
FR2817343A1 (fr) 2002-05-31
DE60110256T2 (de) 2006-03-09
EP1343586B1 (de) 2005-04-20
EP1343586A1 (de) 2003-09-17
AU2002222057A1 (en) 2002-06-11

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