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DE60103732D1 - Pyrimidinderivate mit antitumor-wirkung - Google Patents

Pyrimidinderivate mit antitumor-wirkung

Info

Publication number
DE60103732D1
DE60103732D1 DE60103732T DE60103732T DE60103732D1 DE 60103732 D1 DE60103732 D1 DE 60103732D1 DE 60103732 T DE60103732 T DE 60103732T DE 60103732 T DE60103732 T DE 60103732T DE 60103732 D1 DE60103732 D1 DE 60103732D1
Authority
DE
Germany
Prior art keywords
antitumor effect
alkyl
hydrogen atom
independently hydrogen
pyrimid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60103732T
Other languages
English (en)
Other versions
DE60103732T2 (de
Inventor
Hidekazu Tanaka
Kazuo Ueda
Shinji Suzuki
Hideyuki Takenaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Application granted granted Critical
Publication of DE60103732D1 publication Critical patent/DE60103732D1/de
Publication of DE60103732T2 publication Critical patent/DE60103732T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE60103732T 2000-01-14 2001-01-09 Pyrimidinderivate mit antitumor-wirkung Expired - Fee Related DE60103732T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2000005553 2000-01-14
JP2000005553 2000-01-14
PCT/JP2001/000036 WO2001051488A1 (fr) 2000-01-14 2001-01-09 Derives de la pyrimidine a effet anti-tumoral

Publications (2)

Publication Number Publication Date
DE60103732D1 true DE60103732D1 (de) 2004-07-15
DE60103732T2 DE60103732T2 (de) 2005-06-30

Family

ID=18534207

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60103732T Expired - Fee Related DE60103732T2 (de) 2000-01-14 2001-01-09 Pyrimidinderivate mit antitumor-wirkung

Country Status (10)

Country Link
US (1) US6800630B2 (de)
EP (1) EP1251129B1 (de)
KR (1) KR20020079779A (de)
CN (1) CN1416429A (de)
AT (1) ATE268769T1 (de)
AU (1) AU2001225466A1 (de)
CA (1) CA2396324A1 (de)
DE (1) DE60103732T2 (de)
ES (1) ES2222331T3 (de)
WO (1) WO2001051488A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE208772T1 (de) * 1993-10-01 2001-11-15 Novartis Erfind Verwalt Gmbh Pharmacologisch wirksame pyridinderivate und verfahren zu deren herstellung
US5608067A (en) * 1993-12-09 1997-03-04 Afonso; Adriano 4-substituted pyrazoloquinoline derivatives
US5439918A (en) * 1994-03-14 1995-08-08 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
KR20010071936A (ko) * 1998-07-16 2001-07-31 시오노 요시히코 항종양 활성을 갖는 피리미딘 유도체

Also Published As

Publication number Publication date
WO2001051488A1 (fr) 2001-07-19
US20030203894A1 (en) 2003-10-30
CA2396324A1 (en) 2001-07-19
EP1251129A4 (de) 2003-03-05
KR20020079779A (ko) 2002-10-19
US6800630B2 (en) 2004-10-05
CN1416429A (zh) 2003-05-07
ES2222331T3 (es) 2005-02-01
EP1251129A1 (de) 2002-10-23
EP1251129B1 (de) 2004-06-09
DE60103732T2 (de) 2005-06-30
ATE268769T1 (de) 2004-06-15
AU2001225466A1 (en) 2001-07-24

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee