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DE60035925D1 - Verfahren zur Herstellung von Cephalosporin-Derivaten - Google Patents

Verfahren zur Herstellung von Cephalosporin-Derivaten

Info

Publication number
DE60035925D1
DE60035925D1 DE60035925T DE60035925T DE60035925D1 DE 60035925 D1 DE60035925 D1 DE 60035925D1 DE 60035925 T DE60035925 T DE 60035925T DE 60035925 T DE60035925 T DE 60035925T DE 60035925 D1 DE60035925 D1 DE 60035925D1
Authority
DE
Germany
Prior art keywords
chem
general formula
cephalosporin derivatives
preparation
cephalosporin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60035925T
Other languages
English (en)
Other versions
DE60035925T2 (de
Inventor
Paul Spurr
Georg Trickes
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Basilea Pharmaceutica AG
Original Assignee
Basilea Pharmaceutica AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica AG filed Critical Basilea Pharmaceutica AG
Publication of DE60035925D1 publication Critical patent/DE60035925D1/de
Application granted granted Critical
Publication of DE60035925T2 publication Critical patent/DE60035925T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE60035925T 1999-07-05 2000-06-29 Verfahren zur Herstellung von Cephalosporin-Derivaten Expired - Lifetime DE60035925T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99112911 1999-07-05
EP99112911 1999-07-05

Publications (2)

Publication Number Publication Date
DE60035925D1 true DE60035925D1 (de) 2007-09-27
DE60035925T2 DE60035925T2 (de) 2008-05-15

Family

ID=8238511

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60035925T Expired - Lifetime DE60035925T2 (de) 1999-07-05 2000-06-29 Verfahren zur Herstellung von Cephalosporin-Derivaten

Country Status (10)

Country Link
US (1) US6384214B1 (de)
EP (1) EP1067131B1 (de)
JP (1) JP4033608B2 (de)
KR (1) KR20010049719A (de)
CN (1) CN1292380A (de)
AT (1) ATE370146T1 (de)
CA (1) CA2313379A1 (de)
DE (1) DE60035925T2 (de)
DK (1) DK1067131T3 (de)
ES (1) ES2291159T3 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012528102A (ja) 2009-05-25 2012-11-12 サンド・アクチエンゲゼルシヤフト セフトビプロールメドカリルの製造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523400A (en) 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
ATE227728T1 (de) 1993-04-16 2002-11-15 Basilea Pharmaceutica Ag Cephalosporin-derivate
US5856474A (en) * 1994-04-25 1999-01-05 Biochemie Gesellschaft, M.B.H. Cephalosporin synthesis
EP0761673A1 (de) * 1995-09-12 1997-03-12 F. Hoffmann-La Roche Ag Cephalosporin-Derivate
EP0831093A1 (de) * 1996-09-23 1998-03-25 F. Hoffmann-La Roche Ag 1-Carba-(desthia)-cephalosporinderivate
TW415949B (en) 1996-12-19 2000-12-21 Hoffmann La Roche Vinyl pyrrolidine cephalosporin derivatives with basic substituents
WO2000032605A1 (en) * 1998-12-03 2000-06-08 F. Hoffmann-La Roche Ag Bi-pyrrolidinylvinl (carba) cephalosporins

Also Published As

Publication number Publication date
ES2291159T3 (es) 2008-03-01
CA2313379A1 (en) 2001-01-05
CN1292380A (zh) 2001-04-25
KR20010049719A (ko) 2001-06-15
JP4033608B2 (ja) 2008-01-16
ATE370146T1 (de) 2007-09-15
EP1067131A1 (de) 2001-01-10
JP2001055392A (ja) 2001-02-27
US6384214B1 (en) 2002-05-07
EP1067131B1 (de) 2007-08-15
DK1067131T3 (da) 2007-12-10
DE60035925T2 (de) 2008-05-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition