DE60015471D1 - Chinolin-4-yl-derivate - Google Patents
Chinolin-4-yl-derivateInfo
- Publication number
- DE60015471D1 DE60015471D1 DE60015471T DE60015471T DE60015471D1 DE 60015471 D1 DE60015471 D1 DE 60015471D1 DE 60015471 T DE60015471 T DE 60015471T DE 60015471 T DE60015471 T DE 60015471T DE 60015471 D1 DE60015471 D1 DE 60015471D1
- Authority
- DE
- Germany
- Prior art keywords
- quinolin
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/233—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99119539 | 1999-10-01 | ||
EP99119539 | 1999-10-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60015471D1 true DE60015471D1 (de) | 2004-12-09 |
DE60015471T2 DE60015471T2 (de) | 2005-10-27 |
Family
ID=8239107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60015471T Expired - Fee Related DE60015471T2 (de) | 1999-10-01 | 2000-09-26 | Chinolin-4-yl-derivate |
Country Status (26)
Country | Link |
---|---|
US (1) | US6440995B1 (de) |
JP (1) | JP3523174B2 (de) |
KR (1) | KR100398561B1 (de) |
CN (1) | CN1181059C (de) |
AR (1) | AR025882A1 (de) |
AT (1) | ATE281436T1 (de) |
AU (1) | AU774363B2 (de) |
BR (1) | BR0004548A (de) |
CA (1) | CA2321324A1 (de) |
CO (1) | CO5200789A1 (de) |
CZ (1) | CZ20003575A3 (de) |
DE (1) | DE60015471T2 (de) |
ES (1) | ES2230017T3 (de) |
HR (1) | HRP20000639A2 (de) |
HU (1) | HUP0003861A3 (de) |
ID (1) | ID27525A (de) |
IL (1) | IL138777A0 (de) |
MA (1) | MA26752A1 (de) |
NO (1) | NO20004892L (de) |
NZ (1) | NZ507141A (de) |
PE (1) | PE20010648A1 (de) |
PL (1) | PL342876A1 (de) |
PT (1) | PT1088818E (de) |
SG (1) | SG164268A1 (de) |
TR (1) | TR200002831A2 (de) |
ZA (1) | ZA200005239B (de) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6831087B2 (en) * | 2001-11-09 | 2004-12-14 | Hoffmann-La Roche Inc. | Pyridine substituted isoquinoline derivatives |
ATE309988T1 (de) * | 2002-02-13 | 2005-12-15 | Hoffmann La Roche | Neue pyridin- und quinolin-derivate |
US7648984B2 (en) * | 2004-07-13 | 2010-01-19 | Glaxo Group Limited | Antibacterial agents |
US20100267712A1 (en) * | 2007-09-27 | 2010-10-21 | The United States of America, as represented by the Secretary, Department of Health and | Isoindoline compounds for the treatment of spinal muscular atrophy and other uses |
AU2015276537B2 (en) * | 2014-06-16 | 2019-03-14 | Fundacion Para La Investigacion Medica Aplicada | Novel compounds as dual inhibitors of histone methyltransferases and dna methyltransferases |
EP3206689B1 (de) * | 2014-10-14 | 2021-12-08 | La Jolla Institute of Allergy & Immunology | Inhibitoren von niedermolekularer protein-tyrosinphosphatase und verwendungen davon |
KR20170074178A (ko) * | 2015-12-21 | 2017-06-29 | 제이엔씨 주식회사 | 중합성 액정 화합물, 조성물, 그 액정 중합막류 및 이들의 용도 |
CN105646462B (zh) * | 2016-01-19 | 2019-04-05 | 河南大学 | 芸香宁碱衍生物、其制备方法及应用 |
EP3619210A4 (de) | 2017-05-01 | 2020-12-02 | Sanford Burnham Prebys Medical Discovery Institute | Inhibitoren von niedermolekularer protein-tyrosinphosphatase (lmptp) und verwendungen davon |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE440008C (de) | 1924-03-29 | 1927-05-04 | I G Farbenindustrie Akt Ges | Verfahren zur Darstellung von Chinolinderivaten |
US4560692A (en) | 1984-07-18 | 1985-12-24 | Hoffmann-La Roche Inc. | 4-Piperidino-2-phenylquinolines |
GB9125515D0 (en) | 1991-11-29 | 1992-01-29 | Merck Sharp & Dohme | Therapeutic agents |
US5441963A (en) | 1991-12-20 | 1995-08-15 | Merrell Dow Pharmaceuticals | Potentiation of NMDA antagonists |
-
2000
- 2000-09-11 US US09/658,934 patent/US6440995B1/en not_active Expired - Fee Related
- 2000-09-26 PT PT00120890T patent/PT1088818E/pt unknown
- 2000-09-26 MA MA26068A patent/MA26752A1/fr unknown
- 2000-09-26 DE DE60015471T patent/DE60015471T2/de not_active Expired - Fee Related
- 2000-09-26 ES ES00120890T patent/ES2230017T3/es not_active Expired - Lifetime
- 2000-09-26 AT AT00120890T patent/ATE281436T1/de not_active IP Right Cessation
- 2000-09-26 NZ NZ507141A patent/NZ507141A/en unknown
- 2000-09-27 SG SG200005551-7A patent/SG164268A1/en unknown
- 2000-09-27 CA CA002321324A patent/CA2321324A1/en not_active Abandoned
- 2000-09-27 CZ CZ20003575A patent/CZ20003575A3/cs unknown
- 2000-09-27 AU AU61324/00A patent/AU774363B2/en not_active Ceased
- 2000-09-27 CO CO00073351A patent/CO5200789A1/es not_active Application Discontinuation
- 2000-09-28 PE PE2000001024A patent/PE20010648A1/es not_active Application Discontinuation
- 2000-09-28 ZA ZA200005239A patent/ZA200005239B/xx unknown
- 2000-09-28 AR ARP000105102A patent/AR025882A1/es not_active Application Discontinuation
- 2000-09-28 CN CNB001292013A patent/CN1181059C/zh not_active Expired - Fee Related
- 2000-09-28 IL IL13877700A patent/IL138777A0/xx unknown
- 2000-09-28 HR HR20000639A patent/HRP20000639A2/hr not_active Application Discontinuation
- 2000-09-29 TR TR2000/02831A patent/TR200002831A2/xx unknown
- 2000-09-29 BR BR0004548-9A patent/BR0004548A/pt not_active IP Right Cessation
- 2000-09-29 NO NO20004892A patent/NO20004892L/no unknown
- 2000-09-29 PL PL00342876A patent/PL342876A1/xx not_active Application Discontinuation
- 2000-09-29 ID IDP20000849D patent/ID27525A/id unknown
- 2000-09-29 KR KR10-2000-0057259A patent/KR100398561B1/ko not_active IP Right Cessation
- 2000-09-29 JP JP2000298078A patent/JP3523174B2/ja not_active Expired - Fee Related
- 2000-09-29 HU HU0003861A patent/HUP0003861A3/hu unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200005239B (en) | 2001-04-16 |
JP3523174B2 (ja) | 2004-04-26 |
CO5200789A1 (es) | 2002-09-27 |
NO20004892D0 (no) | 2000-09-29 |
CZ20003575A3 (cs) | 2001-11-14 |
AR025882A1 (es) | 2002-12-18 |
PE20010648A1 (es) | 2001-06-13 |
TR200002831A3 (tr) | 2001-04-20 |
HUP0003861A3 (en) | 2002-09-30 |
AU774363B2 (en) | 2004-06-24 |
CN1290698A (zh) | 2001-04-11 |
PL342876A1 (en) | 2001-04-09 |
SG164268A1 (en) | 2010-09-29 |
ID27525A (id) | 2001-04-12 |
NO20004892L (no) | 2001-04-02 |
HUP0003861A2 (hu) | 2001-10-28 |
IL138777A0 (en) | 2001-10-31 |
ATE281436T1 (de) | 2004-11-15 |
MA26752A1 (fr) | 2004-12-20 |
AU6132400A (en) | 2001-04-05 |
ES2230017T3 (es) | 2005-05-01 |
US6440995B1 (en) | 2002-08-27 |
DE60015471T2 (de) | 2005-10-27 |
HRP20000639A2 (en) | 2001-06-30 |
KR100398561B1 (ko) | 2003-09-19 |
TR200002831A2 (tr) | 2001-04-20 |
CN1181059C (zh) | 2004-12-22 |
CA2321324A1 (en) | 2001-04-01 |
PT1088818E (pt) | 2005-03-31 |
NZ507141A (en) | 2002-05-31 |
KR20010050738A (ko) | 2001-06-15 |
BR0004548A (pt) | 2001-05-29 |
JP2001097952A (ja) | 2001-04-10 |
HU0003861D0 (en) | 2000-12-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |