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DE4244474A1 - HPLC micro-column for high-pressure liquid chromatography - Google Patents

HPLC micro-column for high-pressure liquid chromatography

Info

Publication number
DE4244474A1
DE4244474A1 DE19924244474 DE4244474A DE4244474A1 DE 4244474 A1 DE4244474 A1 DE 4244474A1 DE 19924244474 DE19924244474 DE 19924244474 DE 4244474 A DE4244474 A DE 4244474A DE 4244474 A1 DE4244474 A1 DE 4244474A1
Authority
DE
Germany
Prior art keywords
column
micro
hplc
pressure liquid
liquid chromatography
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19924244474
Other languages
German (de)
Inventor
Edgar Grom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to DE19924244474 priority Critical patent/DE4244474A1/en
Publication of DE4244474A1 publication Critical patent/DE4244474A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6004—Construction of the column end pieces
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6091—Cartridges

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)

Abstract

HPLC micro-column for high-pressure liquid chromatography has a micro-adapter and column head for columns of outside dia. 3-7 mm and inside dia. 3-0.5 mm.

Description

HPLC-Mikro Säule mit Mikro Adapter und SäulenkopfHPLC micro column with micro adapter and column head

HPLC-Säulen sind Teil eines Hochdruckflüssigkeitschromatographen und werden zur Auftrennung fast aller löslichen Substanzen verwendet. Mikro-HPLC-Säulen (ID kleiner als 3mm) haben den Vorteil größerer Empfindlichkeit bei der Detektion, sowie eines geringeren Lösungsmittelverbrauches.HPLC columns are part of a high pressure liquid chromatograph and are used to separate almost all soluble substances. Micro HPLC columns (ID less than 3mm) have the advantage of larger ones Sensitivity in detection, as well as less Solvent consumption.

Die zur Zeit eingesetzten Mikro-"Säulen" mit Edelstahlsieben mit einem Außendurchmesser von 6 mm und einem Innendurchmesser von 2,5 bis 1 mm können nur als Kartuschen mit speziellen Anschlüssen verwendet werden. Dies hat zur Folge, daß teilweise die Säulenanschlüsse der HPLC-Anlagen umgebaut werden müssen. Der Erfindung liegt die Aufgabe zugrunde Mikro-HPLC-Kartuschen mit Hilfe eines Mikroadapters in eine Säule so umzufunktionieren, so daß diese problemlos an jedes HPLC-System angeschlossen werden kann. Dies wird dadurch erreicht, daß mittels eines Mikroadapters und eines Säulenkopfes die Mikrosäule in jede HPLC-Anlage ohne Veränderung eingesetzt werden kann.The currently used micro "columns" with stainless steel sieves an outer diameter of 6 mm and an inner diameter of 2.5 Up to 1 mm can only be used as cartridges with special connections be used. This has the consequence that the Column connections of the HPLC systems must be converted. The invention has for its object micro-HPLC cartridges Using a micro adapter to convert it into a column so that it can be easily connected to any HPLC system. This is achieved by using a micro adapter and one column head the micro column in every HPLC system without Change can be used.

AusführungsbeispieleEmbodiments

Fig. 1 HPLC-Mikro Säule mit Mikro-Adapter und Säulenkopf. Fig. 1 HPLC micro column with micro adapter and column head.

Claims (1)

HPLC-Mikro Säule, dadurch gekennzeichnet, daß mittels Mikroadapter und Säulenkopf die Säule universell anschließbar ist. Dies betrifft HPLC-Säulen mit:
  • a) Außendurchmesser 3-7 mm
  • b) Innendurchmesser 3-0,5 mm
HPLC micro column, characterized in that the column can be connected universally by means of a micro adapter and column head. This applies to HPLC columns with:
  • a) Outside diameter 3-7 mm
  • b) Inner diameter 3-0.5 mm
DE19924244474 1992-12-30 1992-12-30 HPLC micro-column for high-pressure liquid chromatography Withdrawn DE4244474A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE19924244474 DE4244474A1 (en) 1992-12-30 1992-12-30 HPLC micro-column for high-pressure liquid chromatography

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19924244474 DE4244474A1 (en) 1992-12-30 1992-12-30 HPLC micro-column for high-pressure liquid chromatography

Publications (1)

Publication Number Publication Date
DE4244474A1 true DE4244474A1 (en) 1994-07-07

Family

ID=6476787

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19924244474 Withdrawn DE4244474A1 (en) 1992-12-30 1992-12-30 HPLC micro-column for high-pressure liquid chromatography

Country Status (1)

Country Link
DE (1) DE4244474A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009109037A1 (en) * 2008-03-07 2009-09-11 The University Of British Colu Self-contained capillary electrophoresis system for interfacing with mass spectrometry
US20120079874A1 (en) * 2008-12-10 2012-04-05 Anderson Jr James Chromatography Columns

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009109037A1 (en) * 2008-03-07 2009-09-11 The University Of British Colu Self-contained capillary electrophoresis system for interfacing with mass spectrometry
US8613845B2 (en) 2008-03-07 2013-12-24 The University Of British Columbia Self contained capillary electrophoresis system for interfacing with mass spectrometry
US20120079874A1 (en) * 2008-12-10 2012-04-05 Anderson Jr James Chromatography Columns

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee