DE3876877D1 - Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus. - Google Patents

Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus.

Info

Publication number: DE3876877D1
Authority: DE; Germany
Prior art keywords: treatment; indolon; parkinsonism; derivatives; production
Prior art date: 1987-05-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE8888304555T

Other languages

English (en)

Other versions

DE3876877T2 (de

Inventor

David Andrew Arlwydd Owen

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Smith Kline and French Laboratories Ltd

Original Assignee

Smith Kline and French Laboratories Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-05-21

Filing date

1988-05-19

Publication date

1993-02-04

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10617727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3876877(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1988-05-19 Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd

1993-02-04 Application granted granted Critical

1993-02-04 Publication of DE3876877D1 publication Critical patent/DE3876877D1/de

1993-04-29 Publication of DE3876877T2 publication Critical patent/DE3876877T2/de

2008-05-20 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Neurosurgery (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

DE8888304555T 1987-05-21 1988-05-19 Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus. Expired - Lifetime DE3876877T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB878712073A GB8712073D0 (en)	1987-05-21	1987-05-21	Medicament

Publications (2)

Publication Number	Publication Date
DE3876877D1 true DE3876877D1 (de)	1993-02-04
DE3876877T2 DE3876877T2 (de)	1993-04-29

Family

ID=10617727

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8888304555T Expired - Lifetime DE3876877T2 (de)	1987-05-21	1988-05-19	Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus.

Country Status (21)

Country	Link
US (2)	US4824860A (de)
EP (1)	EP0299602B1 (de)
JP (1)	JPH062672B2 (de)
AT (1)	ATE83659T1 (de)
AU (1)	AU599792B2 (de)
CA (1)	CA1305421C (de)
DE (1)	DE3876877T2 (de)
DK (1)	DK169609B1 (de)
ES (1)	ES2052717T3 (de)
GB (1)	GB8712073D0 (de)
GR (1)	GR3007251T3 (de)
HK (1)	HK1000913A1 (de)
HU (1)	HU201871B (de)
IE (1)	IE63511B1 (de)
LU (1)	LU90098I2 (de)
MX (1)	MX9203543A (de)
NL (1)	NL970006I2 (de)
NZ (1)	NZ224709A (de)
PH (1)	PH23867A (de)
PT (1)	PT87542B (de)
ZA (1)	ZA883602B (de)

Families Citing this family (41)

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GB9008605D0 (en) *	1990-04-17	1990-06-13	Smith Kline French Lab	Process
GB9015095D0 (en) *	1990-07-09	1990-08-29	Smith Kline French Lab	Therapeutic method
AU4312593A (en) *	1992-05-18	1993-12-13	Smithkline Beecham Plc	Use of indolone derivatives for the treatment of memory disorders, sexual dysfunction and Parkinson's disease
GB9300309D0 (en) *	1993-01-08	1993-03-03	Smithkline Beecham Plc	Process
GB9511366D0 (en) *	1995-06-06	1995-08-02	Smithkline Beecham Plc	Novel formulations
GB9517062D0 (en) *	1995-08-18	1995-10-25	Scherer Ltd R P	Pharmaceutical compositions
US5807570A (en) *	1995-09-29	1998-09-15	Cygnus, Inc.	Transdermal administration of ropinirole and analogs thereof
GB9612752D0 (en) *	1996-06-19	1996-08-21	Smithkline Beecham Plc	Novel treatment
AU4088897A (en) *	1996-08-27	1998-03-19	American Home Products Corporation	4-aminoethoxy indolone derivatives
AR014847A1 (es) *	1998-04-13	2001-03-28	American Home Prod	4-amino-(etilamino)-oxindoles agonistas del autoreceptor de dopamina y una composicion farmaceutica que los comprende
US6176242B1 (en)	1999-04-30	2001-01-23	Medtronic Inc	Method of treating manic depression by brain infusion
US6218421B1 (en) *	1999-07-01	2001-04-17	Smithkline Beecham P.L.C.	Method of promoting smoking cessation
AR030557A1 (es) *	2000-04-14	2003-08-27	Jagotec Ag	Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6277875B1 (en) *	2000-07-17	2001-08-21	Andrew J. Holman	Use of dopamine D2/D3 receptor agonists to treat fibromyalgia
DE10041478A1 (de) *	2000-08-24	2002-03-14	Sanol Arznei Schwarz Gmbh	Neue pharmazeutische Zusammensetzung
US7858602B2 (en) *	2000-10-16	2010-12-28	Rodriguez Victorio C	Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging disorders due to oxidative stress and as growth factors of stem cells
US6871098B2 (en) *	2000-10-30	2005-03-22	Medtronic, Inc.	Method for treating obsessive-compulsive disorder with electrical stimulation of the brain internal capsule
ATE358488T1 (de) *	2002-09-13	2007-04-15	Motac Neuroscience Ltd	Behandlung von dyskinesie mit 2,3-benzodiazepinen
PT1539135E (pt) *	2002-09-17	2007-07-12	Motac Neuroscience Ltd	Tratamento da discinesia.
DE10334187A1 (de) *	2003-07-26	2005-03-03	Schwarz Pharma Ag	Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) *	2003-07-26	2007-07-05	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung von Depressionen
US20050250803A1 (en) *	2003-11-26	2005-11-10	Pfizer Inc	Combination of dopamine agonists and monoamine reuptake inhibitors
DE10361258A1 (de) *	2003-12-24	2005-07-28	Schwarz Pharma Ag	Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
US7378439B2 (en) *	2004-01-20	2008-05-27	Usv, Ltd.	Process for the preparation of 4-(2-dipropylaminoethyl)-1,3-dihydro-2H-indol-2-one hydrochloride
US20050197385A1 (en) *	2004-02-20	2005-09-08	Schwarz Pharma Ag	Use of rotigotine for treatment or prevention of dopaminergic neuron loss
DE102004014841B4 (de) *	2004-03-24	2006-07-06	Schwarz Pharma Ag	Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
WO2007048034A2 (en) *	2005-10-21	2007-04-26	Caritas St. Elizabeth Medical Center Of Boston, Inc.	Use of androgens for the treatment of parkinson' s disease
US8475829B2 (en) *	2006-04-06	2013-07-02	Nupathe Inc.	Implants for the treatment of dopamine associated states
WO2008001204A2 (en) *	2006-06-29	2008-01-03	Antares Pharma Ipl Ag	Transdermal compositions of pramipexole having enhanced permeation properties
TW200815045A (en) *	2006-06-29	2008-04-01	Jazz Pharmaceuticals Inc	Pharmaceutical compositions of ropinirole and methods of use thereof
US20090247537A1 (en) *	2008-03-25	2009-10-01	William Dale Overfield	Methods for preventing or treating bruxism using dopaminergic agents
CN101574341B (zh) *	2008-05-05	2012-12-19	北京德众万全医药科技有限公司	一种罗匹尼罗的口服固体药物组合物
US20110195117A1 (en) *	2008-09-01	2011-08-11	Lupin Limited	Controlled release compositions of ropinirole
EP2346494A2 (de)	2008-09-29	2011-07-27	Wockhardt Limited	Dosierform von ropinirol mit verlängerter freisetzung
WO2010044108A2 (en)	2008-10-17	2010-04-22	Rubicon Research Private Limited	Controlled release formulations of ropinirole
US20100233259A1 (en) *	2008-12-12	2010-09-16	Pascal Grenier	Dosage form of ropinirole
CA2793571C (en)	2010-04-30	2015-10-13	Teikoku Pharma Usa, Inc.	Propynylaminoindan transdermal compositions
JP5906302B2 (ja)	2011-03-24	2016-04-20	テイコクファーマユーエスエーインコーポレーテッド	作用剤層および作用剤変換層を含む経皮組成物
US9913812B2 (en)	2011-11-09	2018-03-13	Teikoku Pharma Usa, Inc.	Methods for the treatment of skin neoplasms
US9205061B2 (en)	2012-11-02	2015-12-08	Teikoku Pharma Usa, Inc.	Propynylaminoindan transdermal compositions
US20150313891A1 (en) *	2014-05-02	2015-11-05	Abbvie Inc.	Neuronal nicotinic agonists and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4588740A (en) *	1982-12-07	1986-05-13	Smithkline Beckman Corporation	Pharmaceutical methods using 4-aminoalkyl-2(3H)-indolones
US4452808A (en) *	1982-12-07	1984-06-05	Smithkline Beckman Corporation	4-Aminoalkyl-2(3H)-indolones

1987
- 1987-05-21 GB GB878712073A patent/GB8712073D0/en active Pending
1988
- 1988-05-16 PH PH36934A patent/PH23867A/en unknown
- 1988-05-16 IE IE146988A patent/IE63511B1/en not_active IP Right Cessation
- 1988-05-17 CA CA000566974A patent/CA1305421C/en not_active Expired - Lifetime
- 1988-05-19 AU AU16445/88A patent/AU599792B2/en not_active Expired
- 1988-05-19 NZ NZ224709A patent/NZ224709A/en unknown
- 1988-05-19 DE DE8888304555T patent/DE3876877T2/de not_active Expired - Lifetime
- 1988-05-19 DK DK275488A patent/DK169609B1/da not_active IP Right Cessation
- 1988-05-19 ES ES88304555T patent/ES2052717T3/es not_active Expired - Lifetime
- 1988-05-19 EP EP88304555A patent/EP0299602B1/de not_active Expired - Lifetime
- 1988-05-19 AT AT88304555T patent/ATE83659T1/de active
- 1988-05-19 US US07/196,653 patent/US4824860A/en not_active Expired - Lifetime
- 1988-05-20 HU HU882611A patent/HU201871B/hu unknown
- 1988-05-20 JP JP63124816A patent/JPH062672B2/ja not_active Expired - Lifetime
- 1988-05-20 ZA ZA883602A patent/ZA883602B/xx unknown
- 1988-05-20 PT PT87542A patent/PT87542B/pt not_active IP Right Cessation
1989
- 1989-03-13 US US07/322,386 patent/US4912126A/en not_active Expired - Lifetime
1992
- 1992-06-26 MX MX9203543A patent/MX9203543A/es unknown
1993
- 1993-03-05 GR GR930400472T patent/GR3007251T3/el unknown
1997
- 1997-02-05 NL NL970006C patent/NL970006I2/xx unknown
- 1997-07-16 LU LU90098C patent/LU90098I2/fr unknown
- 1997-12-19 HK HK97102520A patent/HK1000913A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT87542A (pt)	1989-05-31
ATE83659T1 (de)	1993-01-15
EP0299602A3 (en)	1990-06-06
IE881469L (en)	1988-11-21
CA1305421C (en)	1992-07-21
AU1644588A (en)	1988-11-24
DE3876877T2 (de)	1993-04-29
HK1000913A1 (en)	1998-05-08
DK275488D0 (da)	1988-05-19
HUT47217A (en)	1989-02-28
PT87542B (pt)	1992-09-30
GR3007251T3 (de)	1993-07-30
JPS63303966A (ja)	1988-12-12
DK169609B1 (da)	1994-12-27
MX9203543A (es)	1992-07-01
NZ224709A (en)	1997-02-24
GB8712073D0 (en)	1987-06-24
NL970006I2 (nl)	1997-10-01
LU90098I2 (fr)	1997-09-25
US4824860A (en)	1989-04-25
US4912126A (en)	1990-03-27
HU201871B (en)	1991-01-28
ZA883602B (en)	1989-04-26
EP0299602A2 (de)	1989-01-18
DK275488A (da)	1988-11-22
EP0299602B1 (de)	1992-12-23
AU599792B2 (en)	1990-07-26
NL970006I1 (nl)	1997-04-01
PH23867A (en)	1989-11-23
ES2052717T3 (es)	1994-07-16
IE63511B1 (en)	1995-05-03
JPH062672B2 (ja)	1994-01-12

Publication	Publication Date	Title
DE3876877D1 (de)	1993-02-04	Verwendung von indolon-derivaten zur herstellung von arzneimitteln zur behandlung des parkinsonismus.
ATE73331T1 (de)	1992-03-15	Verwendung von tetrahydrobiopterinen zur herstellung eines medikaments zur behandlung von kinderautismus.
NO166448C (no)	1991-07-24	Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazolidindioner.
DE69201948D1 (de)	1995-05-11	Verwendung von 1,3-oxathiolanalogen von nukleosiden zur herstellung eines arzneimittels zur behandlung von hepatitis-b.
GEP20002300B (en)	2000-11-25	Purified Forms of Dnase, Method for Its Production, Pharmaceutical Composition and Use Thereof
HUT43843A (en)	1987-12-28	Process for production of derivatives of benzimidasole and medical compounds containing thereof
ATE135577T1 (de)	1996-04-15	Verwendung von buspiron zur herstellung eines pharmazeutischen präparats zur behandlung der alkoholsucht
ATE123944T1 (de)	1995-07-15	Verwendung von trifluormethylphenyl- tetrahydropyridinen zur herstellung von arzneimitteln zur behandlung anxio-depressiver erkrankungen.
DE3873578D1 (de)	1992-09-17	Verwendung von tetrahydrobenz(c,d)indol-6-carboxamiden zur herstellung von arzneimitteln zur behandlung von angstzustaenden.
ATE107168T1 (de)	1994-07-15	Verwendung von gepiron zur herstellung eines pharmazeutischen präparats zur behandlung atypischer depression.
ATE162076T1 (de)	1998-01-15	Verwendung von nadh und nadph zur herstellung eines arzneimittels zur behandlung von morbus alzheimer
DE69501359D1 (de)	1998-02-12	Verwendung von Phosphatdiestern zur Behandlung von Erkrankungen der Retina
ATE159427T1 (de)	1997-11-15	Anwendung des n-n-butyl-derivates von desoxynojirimycin zur herstellung eines arzneimittels zur inhibierung von hiv-virus
DE69007065D1 (de)	1994-04-07	Verwendung von Diadenosin-5',5'''-p1,p4-tetraphosphat zur Herstellung eines Arzneimittels zur Behandlung von Herzkrankheiten.
ATE55250T1 (de)	1990-08-15	Ifosfamid-lyophilisat und verfahren zu dessen herstellung.
ATE53209T1 (de)	1990-06-15	Piperazinverbindungen, verfahren zu ihrer herstellung, pharmazeutische zusammensetzung und verwendung.
ATE192650T1 (de)	2000-05-15	Verwendung von efaroxan und dessen derivaten zur herstellung eines arzneimittels zur behandlung parkinsonscher krankheit
ATE121623T1 (de)	1995-05-15	Verwendung von quinazolinen zur herstellung eines arzneimittels zur behandlung und vorbeugung von arrhythmie.
ATE173921T1 (de)	1998-12-15	Verwendung von deoxyspergualin zur herstellung eines arzneimittels zur behandlung von entzündlich-hyperreaktiven erkrankungen
GB8608893D0 (en)	1986-05-14	D-nor-7-ergoline derivatives
HUT38920A (en)	1986-07-28	Process for producing anticonvulsive tetrahydro-1,2,4-oxadiazine-5-thion derivatives
ATE95174T1 (de)	1993-10-15	1,4-dihydropyridin-derivate, verfahren zu ihrer herstellung, pharmazeutische zusammensetzung und ihre verwendung.

Legal Events

Date	Code	Title	Description
1994-01-27	8364	No opposition during term of opposition
1997-02-06	V448	Application of spc	Free format text: PRODUCT NAME: ROPINIROL HCL; REGISTRATION NO/DATE: 38707.00.00, 38707.01.00, 38707.02.00, 38707.03.00, 38707.04.00; 19961218 Spc suppl protection certif: 197 75 006 Filing date: 19970206
1998-01-23	V457	Spc granted	Free format text: PRODUCT NAME: ROPINIROL HCL; REGISTRATION NO/DATE: 38707.00.00, 38707.01.00, 38707.02.00, 38707.03.00, 38707.04.00; 19961218 Spc suppl protection certif: 197 75 006 Filing date: 19970206
2013-01-31	R071	Expiry of right	Spc suppl protection certif: 19775006 Filing date: 19970206 Expiry date: 20080520 Extension date: 20110702 Effective date: 20110703