DE3861252D1 - Antihypercholesterinaemische verbindungen. - Google Patents

Antihypercholesterinaemische verbindungen.

Info

Publication number: DE3861252D1
Authority: DE; Germany
Prior art keywords: antihypercholesterinaemic; compounds; antihypercholesterinaemic compounds
Prior art date: 1987-03-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE8888302139T

Other languages

English (en)

Inventor

Gerald E Stokker

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Merck and Co Inc

Original Assignee

Merck and Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-03-17

Filing date

1988-03-11

Publication date

1991-01-24

1988-03-11 Application filed by Merck and Co Inc filed Critical Merck and Co Inc

1991-01-24 Application granted granted Critical

1991-01-24 Publication of DE3861252D1 publication Critical patent/DE3861252D1/de

2008-03-12 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

DE8888302139T 1987-03-17 1988-03-11 Antihypercholesterinaemische verbindungen. Expired - Fee Related DE3861252D1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/026,512 US4789682A (en)	1987-03-17	1987-03-17	Antihypercholesterolemic compounds

Publications (1)

Publication Number	Publication Date
DE3861252D1 true DE3861252D1 (de)	1991-01-24

Family

ID=21832262

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8888302139T Expired - Fee Related DE3861252D1 (de)	1987-03-17	1988-03-11	Antihypercholesterinaemische verbindungen.

Country Status (4)

Country	Link
US (1)	US4789682A (de)
EP (1)	EP0283217B1 (de)
JP (1)	JPS6463578A (de)
DE (1)	DE3861252D1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO881411L (no) *	1987-04-14	1988-10-17	Bayer Ag	Substituerte pyrroler.
US5522817A (en) *	1989-03-31	1996-06-04	United States Surgical Corporation	Absorbable surgical fastener with bone penetrating elements
US4970221A (en) *	1989-07-28	1990-11-13	E. R. Squibb & Sons, Inc.	3,5-dihydroxypentanoic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
US5106992A (en) *	1989-07-28	1992-04-21	E. R. Squibb & Sons, Inc.	3,5-dihydroxypentanoic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
DE3929913A1 (de) *	1989-09-08	1991-04-04	Hoechst Ag	4-hydroxytetrahydropyran-2-one sowie die entsprechenden dihydroxycarbonsaeurederivate, salze und ester, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate sowie vorprodukte
US5244887A (en) *	1992-02-14	1993-09-14	Straub Carl D	Stanols to reduce cholesterol absorption from foods and methods of preparation and use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4375475A (en) *	1979-08-17	1983-03-01	Merck & Co., Inc.	Substituted pyranone inhibitors of cholesterol synthesis
US4710513A (en) *	1979-08-17	1987-12-01	Merck & Co., Inc.	Substituted pyranone inhibitors of cholesterol synthesis
US4647576A (en) *	1984-09-24	1987-03-03	Warner-Lambert Company	Trans-6-[2-(substitutedpyrrol-1-yl)alkyl]-pyran-2-one inhibitors of cholesterol synthesis
US4668699A (en) *	1985-08-05	1987-05-26	Merck & Co., Inc.	Novel HMG-CoA reductase inhibitors
DE3669874D1 (de) *	1985-08-29	1990-05-03	Hoechst Ag	3-desmethyl-mevalonsaeurederivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen, ihre verwendung sowie zwischenprodukte.
US4654363A (en) *	1985-11-04	1987-03-31	Merck & Co., Inc.	Synthetic analogs of mevinolin
DE3615620A1 (de) *	1986-05-09	1987-11-12	Hoechst Ag	4(r)-substituierte 6(s)-phenoxymethyl-, 6(s)-(beta)-phenylaethyl-und 6(s)-(beta)-styryl-tetrahydropyran-2-one, ein hochstereoselektives verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung

1987
- 1987-03-17 US US07/026,512 patent/US4789682A/en not_active Expired - Fee Related
1988
- 1988-03-11 DE DE8888302139T patent/DE3861252D1/de not_active Expired - Fee Related
- 1988-03-11 EP EP88302139A patent/EP0283217B1/de not_active Expired - Lifetime
- 1988-03-17 JP JP63062075A patent/JPS6463578A/ja active Pending

Also Published As

Publication number	Publication date
EP0283217B1 (de)	1990-12-12
JPS6463578A (en)	1989-03-09
EP0283217A1 (de)	1988-09-21
US4789682A (en)	1988-12-06

Publication	Publication Date	Title
DE3881970D1 (de)	1993-07-29	Heterocyclische verbindungen.
DE3873936D1 (de)	1992-10-01	Lipoxygenasehemmende verbindungen.
DE3769049D1 (de)	1991-05-08	Heterocyclische verbindungen.
DE3675422D1 (de)	1990-12-13	Lipoxygenasehemmende verbindungen.
DE69005858D1 (de)	1994-02-24	Heterocyclische Verbindungen.
ES2019932B3 (es)	1991-07-16	Compuestos macrolidos.
DE3888821D1 (de)	1994-05-05	Tricyclische Verbindungen.
DE3675421D1 (de)	1990-12-13	Lypoxygenasehemmende verbindungen.
IT8821018A0 (it)	1988-06-17	Proietto.
NO880809D0 (no)	1988-02-24	Antihyperkloresterolemiske tetrazolforbindelser.
FI896364A0 (fi)	1989-12-29	Borrande skaerverktyg foer traeindustri.
DE68921298D1 (de)	1995-03-30	Herzschützende tocopherolähnliche Verbindungen.
ATE94537T1 (de)	1993-10-15	Arylpiperazinylalkylenphenylheterocyclische verbindungen.
NO166619C (no)	1991-08-21	Trinse for skistav.
DE3861252D1 (de)	1991-01-24	Antihypercholesterinaemische verbindungen.
DE68915928D1 (de)	1994-07-14	Benzoheterozyklische Verbindungen.
DE3578424D1 (de)	1990-08-02	Quino-benzothiazin-antibakterielle verbindungen.
ATE126217T1 (de)	1995-08-15	Phenoxyheterozyklische verbindungen.
ATE93512T1 (de)	1993-09-15	Oximino-aether-verbindungen.
ATE128711T1 (de)	1995-10-15	Pestizide verbindungen.
DE3784530D1 (de)	1993-04-15	Dicyanobenzanthronverbindungen.
DE3878192D1 (de)	1993-03-18	N-phenyltetrahydrophthalimidverbindungen.
FI880909A (fi)	1988-08-27	Heterocyklyl-2-propyn-1-aminer.
DE3768393D1 (de)	1991-04-11	Alicyclische verbindungen.
ATE123280T1 (de)	1995-06-15	Heterocyclische verbindungen.

Legal Events

Date	Code	Title	Description
1992-01-16	8364	No opposition during term of opposition
1995-03-09	8339	Ceased/non-payment of the annual fee