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DE3852037D1 - Verfahren zur trennung von teilchen nach grösse. - Google Patents

Verfahren zur trennung von teilchen nach grösse.

Info

Publication number
DE3852037D1
DE3852037D1 DE3852037T DE3852037T DE3852037D1 DE 3852037 D1 DE3852037 D1 DE 3852037D1 DE 3852037 T DE3852037 T DE 3852037T DE 3852037 T DE3852037 T DE 3852037T DE 3852037 D1 DE3852037 D1 DE 3852037D1
Authority
DE
Germany
Prior art keywords
particles
size
tangential flow
separating particles
liposomes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3852037T
Other languages
English (en)
Other versions
DE3852037T2 (de
Inventor
Robert Lenk
Anthony Durning
Robert Klimchak
Joel Portnoff
Michelle Tomsho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elan Pharmaceuticals LLC
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26761847&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3852037(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of DE3852037D1 publication Critical patent/DE3852037D1/de
Application granted granted Critical
Publication of DE3852037T2 publication Critical patent/DE3852037T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1277Processes for preparing; Proliposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1617Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • GPHYSICS
    • G03PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03BAPPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B2227/00Photographic printing apparatus
    • G03B2227/32Projection printing apparatus, e.g. enlarging apparatus, copying camera
    • G03B2227/325Microcapsule copiers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Devices And Processes Conducted In The Presence Of Fluids And Solid Particles (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE3852037T 1987-07-29 1988-07-28 Verfahren zur trennung von teilchen nach grösse. Expired - Lifetime DE3852037T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7930987A 1987-07-29 1987-07-29
US16458088A 1988-03-07 1988-03-07
PCT/US1988/002598 WO1989000846A1 (en) 1987-07-29 1988-07-28 Method for size separation of particles

Publications (2)

Publication Number Publication Date
DE3852037D1 true DE3852037D1 (de) 1994-12-08
DE3852037T2 DE3852037T2 (de) 1995-03-23

Family

ID=26761847

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3852037T Expired - Lifetime DE3852037T2 (de) 1987-07-29 1988-07-28 Verfahren zur trennung von teilchen nach grösse.

Country Status (5)

Country Link
EP (1) EP0394265B1 (de)
JP (1) JP2877160B2 (de)
AT (1) ATE113468T1 (de)
DE (1) DE3852037T2 (de)
WO (1) WO1989000846A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049392A (en) * 1989-01-18 1991-09-17 The Liposome Company, Inc. Osmotically dependent vesicles
US5958449A (en) 1992-12-02 1999-09-28 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for bacterial infections
AU3244393A (en) * 1992-12-02 1994-06-22 Vestar, Inc. Antibiotic formulation and process
US5759571A (en) * 1993-05-11 1998-06-02 Nexstar Pharmaceuticals, Inc. Antibiotic formulation and use for drug resistant infections
DE69426884T2 (de) 1993-07-08 2001-06-21 The Liposome Co.,Inc. Verfahren zum kontrollieren der liposomengrösse
IL115849A0 (en) * 1994-11-03 1996-01-31 Merz & Co Gmbh & Co Tangential filtration preparation of liposomal drugs and liposome product thereof
ATE535232T1 (de) 1997-09-18 2011-12-15 Pacira Pharmaceuticals Inc Retardierte freisetzung liposomaler anesthetischer zusammensetzungen
ATE554748T1 (de) * 1997-11-14 2012-05-15 Pacira Pharmaceuticals Inc Herstellung von multivesikulären liposomen
US6165997A (en) * 1997-11-20 2000-12-26 Statens Serum Institut Phospholipids having antimicrobial activity with or without the presence of antimicrobials
FR2788780B1 (fr) * 1999-01-27 2001-03-30 Ap Cells Inc Procede de preparation de vesicules membranaires
US20050271731A1 (en) * 2002-09-11 2005-12-08 Akira Suzuki Process for the production of microspheres and unit therefor
US8182590B2 (en) * 2005-04-29 2012-05-22 University Of Rochester Ultrathin porous nanoscale membranes, methods of making, and uses thereof
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
KR101706178B1 (ko) 2008-06-16 2017-02-15 화이자 인코포레이티드 약물 부하된 중합체성 나노입자, 및 이의 제조 및 사용 방법
ES2721850T3 (es) 2008-06-16 2019-08-05 Pfizer Nanopartículas poliméricas terapéuticas que comprenden alcaloides vinca y procedimientos de fabricación y uso de las mismas
WO2010005726A2 (en) 2008-06-16 2010-01-14 Bind Biosciences Inc. Therapeutic polymeric nanoparticles with mtor inhibitors and methods of making and using same
EA201100765A1 (ru) 2008-12-15 2012-04-30 Бинд Биосаиэнсис Наночастицы длительной циркуляции для замедленного высвобождения терапевтических средств
GB0917003D0 (en) * 2009-09-28 2009-11-11 Novartis Vaccines Inst For Global Health Srl Purification of bacterial vesicles
WO2011072218A2 (en) 2009-12-11 2011-06-16 Bind Biosciences Stable formulations for lyophilizing therapeutic particles
ES2780156T3 (es) 2009-12-15 2020-08-24 Pfizer Composiciones terapéuticas de nanopartículas poliméricas con alta temperatura de transición vítrea o copolímeros de alto peso molecular
EP2402075A1 (de) 2010-06-28 2012-01-04 Bühler AG Verfahren und Vorrichtung zur Herstellung von Vesikeln
ES2848025T3 (es) 2012-09-04 2021-08-05 Eleison Pharmaceuticals LLC Prevención de la recidiva pulmonar del cáncer con cisplatino complejado con lípidos
US9877923B2 (en) 2012-09-17 2018-01-30 Pfizer Inc. Process for preparing therapeutic nanoparticles
SI3116547T1 (sl) 2014-03-14 2019-08-30 Pfizer, Inc. Terapevtski nanodelci, ki obsegajo terapevtsko stredstvo, in postopek izdelave ter uporabe le-teh
SI3466432T1 (sl) 2014-05-15 2020-11-30 Insmed Incorporated Postopek zdravljenja pljučnih netuberkuloznih mikobakterijskih okužb
CA2953265C (en) * 2014-07-02 2023-09-26 Shire Human Genetic Therapies, Inc. Encapsulation of messenger rna
US11571386B2 (en) 2018-03-30 2023-02-07 Insmed Incorporated Methods for continuous manufacture of liposomal drug products
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0032578B1 (de) * 1980-01-16 1984-07-25 Hans Georg Prof. Dr. Weder Verfahren und Dialysiereinrichtung zur Herstellung von Bilayer-Vesikeln und Verwendung der Bilayer-Vesikel
US4420398A (en) * 1981-08-13 1983-12-13 American National Red Cross Filteration method for cell produced antiviral substances
US4888115A (en) * 1983-12-29 1989-12-19 Cuno, Incorporated Cross-flow filtration
DE3432718C1 (de) * 1984-09-06 1986-05-22 Biotest Pharma GmbH, 6000 Frankfurt Verfahren zur Herstellung einer Loesung von Milch- und/oder Kolostralimmunglobulinen
FR2576805B1 (fr) * 1985-02-01 1989-08-25 Lyonnaise Eaux Appareil de filtration tangentielle
GB2176715A (en) * 1985-06-27 1987-01-07 Apv Int Ltd Beer filtration
IL79985A0 (en) * 1985-09-13 1986-12-31 Ausimont Spa Purification of oils containing solid matter in suspension

Also Published As

Publication number Publication date
EP0394265B1 (de) 1994-11-02
JPH02504362A (ja) 1990-12-13
WO1989000846A1 (en) 1989-02-09
DE3852037T2 (de) 1995-03-23
JP2877160B2 (ja) 1999-03-31
EP0394265A4 (en) 1991-07-31
ATE113468T1 (de) 1994-11-15
EP0394265A1 (de) 1990-10-31

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8327 Change in the person/name/address of the patent owner

Owner name: ELAN PHARMACEUTICALS,INC.(N.D.GES.D.STAATES DE, US