DE3782986D1 - Verfahren zur trennung von n-geschuetzten alpha-l-aspartyl-l-phenylalaninen. - Google Patents

Verfahren zur trennung von n-geschuetzten alpha-l-aspartyl-l-phenylalaninen.

Info

Publication number: DE3782986D1
Authority: DE; Germany
Prior art keywords: phenylalanines; aspartyl; separating; protected alpha; alpha
Prior art date: 1986-08-11
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE8787307027T

Other languages

English (en)

Other versions

DE3782986T2 (de

Inventor

Toyoto Central Research Hijiya

Tadashi Tokai Plant Takemoto

Toshihide Central Resea Yukaka

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Ajinomoto Co Inc

Original Assignee

Ajinomoto Co Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-08-11

Filing date

1987-08-07

Publication date

1993-01-21

1987-08-07 Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc

1993-01-21 Application granted granted Critical

1993-01-21 Publication of DE3782986D1 publication Critical patent/DE3782986D1/de

1993-04-08 Publication of DE3782986T2 publication Critical patent/DE3782986T2/de

2007-08-08 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/801—Peptide sweetners

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Life Sciences & Earth Sciences (AREA)
Analytical Chemistry (AREA)
Peptides Or Proteins (AREA)

DE8787307027T 1986-08-11 1987-08-07 Verfahren zur trennung von n-geschuetzten alpha-l-aspartyl-l-phenylalaninen. Expired - Fee Related DE3782986T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP61188341A JPS6344594A (ja)	1986-08-11	1986-08-11	Ｎ−保護−α−Ｌ−アスパルチル−Ｌ−フエニルアラニンの分離方法

Publications (2)

Publication Number	Publication Date
DE3782986D1 true DE3782986D1 (de)	1993-01-21
DE3782986T2 DE3782986T2 (de)	1993-04-08

Family

ID=16221920

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8787307027T Expired - Fee Related DE3782986T2 (de)	1986-08-11	1987-08-07	Verfahren zur trennung von n-geschuetzten alpha-l-aspartyl-l-phenylalaninen.

Country Status (6)

Country	Link
US (1)	US4803300A (de)
EP (1)	EP0256812B1 (de)
JP (1)	JPS6344594A (de)
KR (1)	KR900006572B1 (de)
CA (1)	CA1298432C (de)
DE (1)	DE3782986T2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5283357A (en) *	1988-03-14	1994-02-01	Mitsui Toatsu Chemicals, Incorporated	Separation method of α-l-aspartyl-l-phenylalanine methyl ester
JP3178092B2 (ja) *	1992-06-29	2001-06-18	味の素株式会社	α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステル塩酸塩の製造方法
ES2068763B1 (es) *	1993-07-23	1995-10-01	Univ Madrid Complutense	Procedimiento de purificacion del dipeptido *-l-aspartil-l-fenilalanina o de sus esteres alquilicos de bajo peso molecular.
JP3314515B2 (ja) *	1994-03-24	2002-08-12	味の素株式会社	Ｌ−フェニルアラニンの回収方法
JPH07278076A (ja) *	1994-04-12	1995-10-24	Ajinomoto Co Inc	Ｌ−フェニルアラニン・モノメチル硫酸塩の晶析方法
US6657073B1 (en)	1999-08-18	2003-12-02	Daesang Corporation	Crystallization of α-L-aspartyl-L-phenylalanine methyl ester

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3786039A (en) *	1969-04-30	1974-01-15	Ajinomoto Kk	Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters
US3933781A (en) *	1973-11-05	1976-01-20	Monsanto Company	Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
US4173562A (en) *	1976-12-27	1979-11-06	Monsanto Company	Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester
JPS5526133A (en) *	1978-08-11	1980-02-25	Hitachi Ltd	Gripper for tension reel drum
US4480112A (en) *	1983-06-20	1984-10-30	G. D. Searle & Co.	Method and intermediates for producing α-L-aspartyl-L-phenylalanine
IT1175926B (it) *	1984-01-13	1987-08-12	Debi Derivati Biologici	Procedimento per la preparazione dell'estere metilico di alfa-l-aspartil-l-fenilalanina
JPH07636B2 (ja) *	1984-12-17	1995-01-11	三井東圧化学株式会社	Ｎ−ホルミル−α−アスパルチルフエニルアラニンの製造法
US4680403A (en) *	1985-01-17	1987-07-14	Ajinomoto Co., Inc.	Process for producing N-protected-α-L-aspartyl-L-phenylalanine methyl ester
US4677220A (en) *	1985-10-31	1987-06-30	Monsanto Company	Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester

1986
- 1986-08-11 JP JP61188341A patent/JPS6344594A/ja active Pending
1987
- 1987-08-07 EP EP87307027A patent/EP0256812B1/de not_active Expired - Lifetime
- 1987-08-07 DE DE8787307027T patent/DE3782986T2/de not_active Expired - Fee Related
- 1987-08-11 CA CA000544249A patent/CA1298432C/en not_active Expired - Lifetime
- 1987-08-11 US US07/084,162 patent/US4803300A/en not_active Expired - Lifetime
- 1987-08-11 KR KR1019870008788A patent/KR900006572B1/ko not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0256812B1 (de)	1992-12-09
DE3782986T2 (de)	1993-04-08
KR900006572B1 (ko)	1990-09-13
US4803300A (en)	1989-02-07
KR880002895A (ko)	1988-05-12
EP0256812A3 (en)	1989-04-26
EP0256812A2 (de)	1988-02-24
CA1298432C (en)	1992-03-31
JPS6344594A (ja)	1988-02-25

Publication	Publication Date	Title
DE3585147D1 (de)	1992-02-20	Verfahren zur reinigung von proteinen.
DE3864904D1 (de)	1991-10-24	Verfahren zur trennung von folinsaeure.
DE3676392D1 (de)	1991-02-07	Verfahren zur trennung von rohoel.
DE58900407D1 (de)	1991-12-05	Verfahren zur reinigung von rohargon.
DE3769807D1 (de)	1991-06-13	Verfahren zur trennung von lipoproteinen.
DE3783079D1 (de)	1993-01-28	Verfahren zur pyrorekombination von abfallstoffe enthaltenden mischungen.
DE58900372D1 (de)	1991-11-21	Verfahren zur abtrennung von kohlenwasserstoffen.
DE3779671D1 (de)	1992-07-16	Verfahren zur gewinnung von gallium.
DE68900949D1 (de)	1992-04-16	Verfahren zur trennung von wasserstoffbehandlungs-ausfluessen.
DE3483344D1 (de)	1990-11-08	Verfahren zur reinigung von lpf-ha.
DE3678345D1 (de)	1991-05-02	Verfahren zur wegnahme von versteckten linien.
DE3888845D1 (de)	1994-05-05	Verfahren zur entmodulierung.
DE3763186D1 (de)	1990-07-19	Verfahren zur umstrukturierung von olefinen.
DE3780593D1 (de)	1992-08-27	Verfahren zur verhinderung von ablagerungen.
DE3761601D1 (de)	1990-03-08	Verfahren zur aufarbeitung von kleinbatterien.
DE58901598D1 (de)	1992-07-09	Verfahren zur gewinnung von rohargon.
ATE118498T1 (de)	1995-03-15	Verfahren zur reinigung von n- phosphonmethylglyzin.
DE3780364D1 (de)	1992-08-20	Verfahren zur abscheidung von kohlendioxyd.
DE3576148D1 (de)	1990-04-05	Verfahren zur trennung von racematen.
DE3482449D1 (de)	1990-07-19	Verfahren zur trennung von borisotopen.
DE3673060D1 (de)	1990-09-06	Verfahren zur rueckgewinnung von fluorwasserstoff.
DE3672247D1 (de)	1990-08-02	Verfahren zur trennung von toluendiaminen-isomeren.
DE3874510D1 (de)	1992-10-15	Verfahren zur stabilisierung von hydroisomeraten.
DE68902666D1 (de)	1992-10-08	Verfahren zur abtrennung von halogenierten benzolabkoemmlingen.
DE68918000D1 (de)	1994-10-13	Verfahren zur Entfernung von Rückständen.

Legal Events

Date	Code	Title	Description
1994-01-13	8364	No opposition during term of opposition
2003-06-12	8339	Ceased/non-payment of the annual fee