DE3776269D1 - Labetalol tablette mit verzoegerter wirkstoffabgabe. - Google Patents
Labetalol tablette mit verzoegerter wirkstoffabgabe.Info
- Publication number
- DE3776269D1 DE3776269D1 DE8787116021T DE3776269T DE3776269D1 DE 3776269 D1 DE3776269 D1 DE 3776269D1 DE 8787116021 T DE8787116021 T DE 8787116021T DE 3776269 T DE3776269 T DE 3776269T DE 3776269 D1 DE3776269 D1 DE 3776269D1
- Authority
- DE
- Germany
- Prior art keywords
- labetalol
- tablet
- active substances
- delayed delivery
- delayed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- SGUAFYQXFOLMHL-UHFFFAOYSA-N 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide Chemical compound C=1C=C(O)C(C(N)=O)=CC=1C(O)CNC(C)CCC1=CC=CC=C1 SGUAFYQXFOLMHL-UHFFFAOYSA-N 0.000 title 1
- 206010012186 Delayed delivery Diseases 0.000 title 1
- 239000013543 active substance Substances 0.000 title 1
- 229960001632 labetalol Drugs 0.000 title 1
- WQVZLXWQESQGIF-UHFFFAOYSA-N Labetalol hydrochloride Chemical compound Cl.C=1C=C(O)C(C(N)=O)=CC=1C(O)CNC(C)CCC1=CC=CC=C1 WQVZLXWQESQGIF-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000002552 dosage form Substances 0.000 abstract 1
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 1
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 1
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 1
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 1
- 229960003091 labetalol hydrochloride Drugs 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 229920000036 polyvinylpyrrolidone Polymers 0.000 abstract 1
- 239000001267 polyvinylpyrrolidone Substances 0.000 abstract 1
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92630686A | 1986-11-03 | 1986-11-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3776269D1 true DE3776269D1 (de) | 1992-03-05 |
Family
ID=25453030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8787116021T Expired - Lifetime DE3776269D1 (de) | 1986-11-03 | 1987-10-31 | Labetalol tablette mit verzoegerter wirkstoffabgabe. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0266707B1 (de) |
JP (1) | JPS63126825A (de) |
AT (1) | ATE71833T1 (de) |
DE (1) | DE3776269D1 (de) |
GR (1) | GR3003745T3 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2723919B2 (ja) * | 1988-09-02 | 1998-03-09 | エーザイ株式会社 | 環状アミン誘導体を含有する経口用医薬品組成物 |
IT1229856B (it) * | 1989-04-20 | 1991-09-13 | Recordati Chem Pharm | Compresse a rilascio controllato contenenti flavossato. |
DE4001622A1 (de) * | 1990-01-20 | 1991-07-25 | Thomae Gmbh Dr K | Orale arzneimittelformen von pimobendan |
SK281042B6 (sk) | 1992-09-18 | 2000-11-07 | Yamanouchi Pharmaceutical Co., Ltd | Prípravok hydrogélového typu s ustáleným uvoľňovaním |
JP3598049B2 (ja) * | 1992-09-18 | 2004-12-08 | 山之内製薬株式会社 | ハイドロゲル徐放性製剤 |
GB9611328D0 (en) * | 1996-05-31 | 1996-08-07 | Zeneca Ltd | Pharmaceutical compositions |
CN117045610B (zh) * | 2023-08-24 | 2024-04-30 | 杭州沐源生物医药科技有限公司 | 一种溶出高稳定性的盐酸拉贝洛尔组合物及其制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4012444A (en) * | 1969-07-08 | 1977-03-15 | Allen & Hanburys Limited | 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof |
GB1555958A (en) * | 1976-02-27 | 1979-11-14 | Allen & Hanburys Ltd | Amino hydroxyethyl salicylamides processes for their preparation and compositions containing them |
GB2181053B (en) * | 1985-10-01 | 1990-05-23 | Sandoz Ltd | Pharmaceutical formulations with controlled release of the active substance |
FR2588188B1 (fr) * | 1985-10-04 | 1988-01-08 | Delalande Sa | Comprime de sel(s) hydrosoluble(s) de cinepazide a liberation programmee et son procede de preparation |
-
1987
- 1987-10-31 DE DE8787116021T patent/DE3776269D1/de not_active Expired - Lifetime
- 1987-10-31 AT AT87116021T patent/ATE71833T1/de not_active IP Right Cessation
- 1987-10-31 EP EP87116021A patent/EP0266707B1/de not_active Expired - Lifetime
- 1987-11-02 JP JP62278151A patent/JPS63126825A/ja active Pending
-
1992
- 1992-02-07 GR GR920400168T patent/GR3003745T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE71833T1 (de) | 1992-02-15 |
EP0266707A3 (en) | 1989-05-03 |
EP0266707A2 (de) | 1988-05-11 |
JPS63126825A (ja) | 1988-05-30 |
GR3003745T3 (de) | 1993-03-16 |
EP0266707B1 (de) | 1992-01-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |