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DE3773557D1 - Intravaginalartikel und verfahren zu seiner herstellung. - Google Patents

Intravaginalartikel und verfahren zu seiner herstellung.

Info

Publication number
DE3773557D1
DE3773557D1 DE8787107710T DE3773557T DE3773557D1 DE 3773557 D1 DE3773557 D1 DE 3773557D1 DE 8787107710 T DE8787107710 T DE 8787107710T DE 3773557 T DE3773557 T DE 3773557T DE 3773557 D1 DE3773557 D1 DE 3773557D1
Authority
DE
Germany
Prior art keywords
intravaginal
item
production
estradiol
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8787107710T
Other languages
English (en)
Inventor
Inga Marianne Lindskog
Bengt Christer Hans Sjoegren
Sven-Boerje Andersson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Leo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo AB filed Critical Leo AB
Application granted granted Critical
Publication of DE3773557D1 publication Critical patent/DE3773557D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Paper (AREA)
  • Medicinal Preparation (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • External Artificial Organs (AREA)
  • Seal Device For Vehicle (AREA)
  • Window Of Vehicle (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Nonmetallic Welding Materials (AREA)
  • Steroid Compounds (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
DE8787107710T 1986-06-16 1987-05-27 Intravaginalartikel und verfahren zu seiner herstellung. Expired - Lifetime DE3773557D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8602666A SE8602666D0 (sv) 1986-06-16 1986-06-16 Intravaginal devices

Publications (1)

Publication Number Publication Date
DE3773557D1 true DE3773557D1 (de) 1991-11-14

Family

ID=20364821

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787107710T Expired - Lifetime DE3773557D1 (de) 1986-06-16 1987-05-27 Intravaginalartikel und verfahren zu seiner herstellung.

Country Status (22)

Country Link
US (1) US4871543A (de)
EP (1) EP0253109B1 (de)
JP (1) JP2671953B2 (de)
KR (1) KR920005824B1 (de)
CN (1) CN1034391C (de)
AT (1) ATE68097T1 (de)
AU (1) AU599988B2 (de)
CA (1) CA1314482C (de)
DE (1) DE3773557D1 (de)
DK (1) DK175529B1 (de)
ES (1) ES2026481T3 (de)
FI (1) FI91709C (de)
GR (1) GR3003551T3 (de)
HU (1) HU205014B (de)
IE (1) IE60654B1 (de)
IL (1) IL82769A (de)
NO (2) NO172784C (de)
NZ (1) NZ220616A (de)
PH (1) PH26981A (de)
PT (1) PT85082B (de)
SE (1) SE8602666D0 (de)
ZA (1) ZA874174B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5188835A (en) * 1986-06-16 1993-02-23 Kabi Pharmacia Ab Intravaginal devices
US5084277A (en) * 1988-08-30 1992-01-28 Greco John C Vaginal progesterone tablet
FI93922C (fi) * 1993-06-17 1995-06-26 Leiras Oy Vaikuttavaa ainetta luovuttava laite
FI95768C (fi) * 1993-06-17 1996-03-25 Leiras Oy Emättimensisäinen antosysteemi
IL116433A (en) * 1994-12-19 2002-02-10 Galen Chemicals Ltd INTRAVAGINAL DRUG DELIVERY DEVICES FOR THE ADMINISTRATION OF 17β-OESTRADIOL PRECURSORS
US5861431A (en) * 1995-06-07 1999-01-19 Iotek, Inc. Incontinence treatment
US5816248A (en) * 1996-03-29 1998-10-06 Iotek, Inc. Channeled vaginal insert and method for treating urogenital disorders
US6030375A (en) * 1996-03-29 2000-02-29 Iotek, Inc. Compressible vaginal insert and method for treating urogenital disorders
US5988169A (en) * 1996-03-29 1999-11-23 Iotek, Inc. Vaginal insert and method for treating urogenital disorders
US5891868A (en) * 1997-11-21 1999-04-06 Kaiser Foundation Health Plan, Inc. Methods for treating postmenopausal women using ultra-low doses of estrogen
US20030219471A1 (en) * 2002-03-11 2003-11-27 Caubel Patrick Michel Extended cycle estrogen and sulfatase inhibiting progestogen contraceptive regimens
EP1482949A1 (de) * 2002-03-11 2004-12-08 Janssen Pharmaceutica N.V. Sulfatase-hemmendes progestogen als einziges kontrazeptivum enthaltende kontrazeptionsschemas
ES2269999T3 (es) * 2002-03-11 2007-04-01 Janssen Pharmaceutica N.V. Terapia hormonal sustitutiva que inhibe progestageno sulfatasa continua.
CA2523859C (en) * 2003-04-29 2011-08-02 The General Hospital Corporation Methods and devices for the sustained release of multiple drugs
US7816546B2 (en) * 2003-06-30 2010-10-19 Richter Gedeon Vegyeszeti Gyar Rt. Process for the synthesis of high purity d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime
CN102098991B (zh) * 2008-02-04 2014-10-22 特卫华妇女健康有限公司 包含孕酮的一体式阴道环以及其制备方法
WO2021111385A2 (en) 2019-12-06 2021-06-10 Prathima Chowdary Sustained release estrogen vaginal ring pessary for treatment of atrophy, cystitis and uterovaginal prolapse

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920805A (en) * 1971-12-09 1975-11-18 Upjohn Co Pharmaceutical devices and method
IN142428B (de) * 1974-07-05 1977-07-09 Schering Ag
DE2450107A1 (de) * 1974-10-18 1976-04-29 Schering Ag Vaginalring
US4155991A (en) * 1974-10-18 1979-05-22 Schering Aktiengesellschaft Vaginal ring
DE2611535A1 (de) * 1976-03-16 1977-09-29 Schering Ag 6alpha-hydroxy-8alpha-oestradiole
JPS5845440B2 (ja) * 1978-08-29 1983-10-08 呉羽化学工業株式会社 プロスタグランジン誘導体とその製造方法及び薬剤
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
US4250611A (en) * 1979-04-19 1981-02-17 Alza Corporation Process for making drug delivery device with reservoir
US4402695A (en) * 1980-01-21 1983-09-06 Alza Corporation Device for delivering agent in vagina
US4425339A (en) * 1981-04-09 1984-01-10 Syntex (U.S.A.) Inc. Treatment of menopausal symptoms
GB2135189B (en) * 1983-02-22 1986-07-09 Joachim Georg Liehr Estrogen deficiency conditioned with 2-fluoroestradiols
AU582540B2 (en) * 1983-08-05 1989-04-06 Pre Jay Holdings Ltd. A method of hormonal treatment of perimenopausal, menopausal and post-menopausal disorders and multi-preparation pack therefor
EP0180264A1 (de) * 1984-10-12 1986-05-07 Akzo N.V. Entladungssysteme für zwei oder mehrere aktive Substanzen

Also Published As

Publication number Publication date
IL82769A0 (en) 1987-12-20
ES2026481T3 (es) 1992-05-01
IE871377L (en) 1987-12-16
EP0253109B1 (de) 1991-10-09
PH26981A (en) 1992-12-28
NZ220616A (en) 1990-09-26
FI91709C (fi) 1994-08-10
NO872489L (no) 1987-12-17
FI872629A0 (fi) 1987-06-12
HU205014B (en) 1992-03-30
PT85082B (pt) 1990-03-08
NO872489D0 (no) 1987-06-15
KR880000114A (ko) 1988-03-23
IL82769A (en) 1991-07-18
US4871543A (en) 1989-10-03
JPS62298532A (ja) 1987-12-25
ATE68097T1 (de) 1991-10-15
IE60654B1 (en) 1994-08-10
CN87104229A (zh) 1987-12-30
PT85082A (en) 1987-07-01
EP0253109A1 (de) 1988-01-20
AU7422287A (en) 1987-12-17
GR3003551T3 (de) 1993-03-16
CA1314482C (en) 1993-03-16
AU599988B2 (en) 1990-08-02
SE8602666D0 (sv) 1986-06-16
NO1997001I1 (no) 1997-01-13
ZA874174B (en) 1987-12-11
NO172784B (no) 1993-06-01
CN1034391C (zh) 1997-04-02
NO172784C (no) 1993-09-08
DK303487A (da) 1987-12-17
JP2671953B2 (ja) 1997-11-05
HUT44931A (en) 1988-05-30
FI872629A (fi) 1987-12-17
FI91709B (fi) 1994-04-29
DK303487D0 (da) 1987-06-15
DK175529B1 (da) 2004-11-22
KR920005824B1 (ko) 1992-07-20

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Legal Events

Date Code Title Description
8380 Miscellaneous part iii

Free format text: DER PATENTINHABER LAUTET RICHTIG: KABI PHARMACIA AB, UPPSALA, SE

8364 No opposition during term of opposition
V448 Application of spc

Free format text: PRODUCT NAME: ESTRADIOL (ESTRING); REGISTRATION NO/DATE: 29279.00.00, 19960508

Spc suppl protection certif: 196 75 033

Filing date: 19961025

8327 Change in the person/name/address of the patent owner

Owner name: PHARMACIA & UPJOHN AB, STOCKHOLM, SE

V457 Spc granted

Free format text: PRODUCT NAME: ESTRADIOL (ESTRING); REGISTRATION NO/DATE: 29279.00.00, 19960508

Spc suppl protection certif: 196 75 033

Filing date: 19961025

V464 Spc expired

Free format text: PRODUCT NAME: ESTRADIOL (ESTRING); REGISTRATION NO/DATE: 29279.00.00, 19960508

Spc suppl protection certif: 196 75 033

Filing date: 19961025