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DE3765682D1 - Thiolactam-n-essigsaeure-derivate, ihre herstellung und verwendung. - Google Patents

Thiolactam-n-essigsaeure-derivate, ihre herstellung und verwendung.

Info

Publication number
DE3765682D1
DE3765682D1 DE8787302825T DE3765682T DE3765682D1 DE 3765682 D1 DE3765682 D1 DE 3765682D1 DE 8787302825 T DE8787302825 T DE 8787302825T DE 3765682 T DE3765682 T DE 3765682T DE 3765682 D1 DE3765682 D1 DE 3765682D1
Authority
DE
Germany
Prior art keywords
thiolactam
production
acetic acid
acid derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787302825T
Other languages
English (en)
Inventor
Kanji Meguro
Hitoshi Ikeda
Yujiro Yamamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Senju Pharmaceutical Co Ltd
Takeda Pharmaceutical Co Ltd
Original Assignee
Senju Pharmaceutical Co Ltd
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharmaceutical Co Ltd, Takeda Chemical Industries Ltd filed Critical Senju Pharmaceutical Co Ltd
Application granted granted Critical
Publication of DE3765682D1 publication Critical patent/DE3765682D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/16—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8787302825T 1986-04-17 1987-04-01 Thiolactam-n-essigsaeure-derivate, ihre herstellung und verwendung. Expired - Fee Related DE3765682D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8929586 1986-04-17
JP14594186 1986-06-20

Publications (1)

Publication Number Publication Date
DE3765682D1 true DE3765682D1 (de) 1990-11-29

Family

ID=26430721

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787302825T Expired - Fee Related DE3765682D1 (de) 1986-04-17 1987-04-01 Thiolactam-n-essigsaeure-derivate, ihre herstellung und verwendung.

Country Status (19)

Country Link
US (1) US4771050A (de)
EP (1) EP0243018B1 (de)
JP (1) JPS63107970A (de)
KR (1) KR870010024A (de)
CN (1) CN1020098C (de)
AR (1) AR244674A1 (de)
AU (1) AU602641B2 (de)
CA (1) CA1287629C (de)
DE (1) DE3765682D1 (de)
DK (1) DK184587A (de)
ES (1) ES2022889B3 (de)
FI (1) FI89711C (de)
GR (1) GR3001210T3 (de)
HK (1) HK108293A (de)
HU (1) HU198699B (de)
IE (1) IE60246B1 (de)
NO (1) NO167916C (de)
PT (1) PT84704B (de)
SU (1) SU1538895A3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2996475B2 (ja) * 1989-12-22 1999-12-27 サントリー株式会社 ベンズオキサジノン誘導体及びそれを有効成分として含有する除草剤
TW200402B (de) * 1990-08-13 1993-02-21 Senju Pharma Co
AU638154B2 (en) * 1990-10-04 1993-06-17 Suntory Limited Benzoxazine derivative and herbicide containing same as an active ingredient
IE914455A1 (en) * 1990-12-27 1992-07-01 Green Cross Corp 1,4-benzothiazine-2-acetic acid derivatives, processes for production thereof
DE69329618T2 (de) * 1992-08-31 2001-05-17 Santen Pharmaceutical Co., Ltd 3-oxo-1,4-benzothiazin-derivate
JP3126541B2 (ja) * 1993-03-26 2001-01-22 千寿製薬株式会社 ベンゾチアゾール誘導体、その製法及びその用途
WO1995013269A1 (fr) * 1993-11-12 1995-05-18 Santen Pharmaceutical Co., Ltd. Derive de 1,4-benzothiazine
CN100378118C (zh) * 1997-04-15 2008-04-02 Csir公司 具有食欲抑制剂活性的药物组合物
GB2355657B (en) * 1999-10-27 2004-07-28 Phytopharm Plc Inhibitors Of Gastric Acid Secretion
US6713477B1 (en) 2000-04-19 2004-03-30 Sumitomo Pharmaceuticals Company, Limited Hydroxamic acid derivatives
GB2363985B (en) 2000-06-30 2004-09-29 Phytopharm Plc Extracts,compounds & pharmaceutical compositions having anti-diabetic activity and their use
AU2002215160A1 (en) 2000-11-30 2002-06-11 Pfizer Products Inc. Combination of gaba agonists and aldose reductase inhibitors
WO2005082872A1 (ja) * 2004-03-02 2005-09-09 Dainippon Sumitomo Pharma Co., Ltd. ベンゾチアジン－３－オン化合物及びその製造中間体
US20110092566A1 (en) * 2004-11-19 2011-04-21 Srivastava Satish K Treatment of cancer with aldose reductase inhibitors
US20070197512A1 (en) * 2006-01-27 2007-08-23 Japan Tobacco Inc. Carboxylic Acid Compounds and Use Thereof
WO2007086504A1 (ja) * 2006-01-27 2007-08-02 Japan Tobacco Inc. カルボン酸化合物及びその用途
EP2368560A1 (de) 2007-03-12 2011-09-28 Zadec ApS Antidiabetes-Extrakt von Rooibos
EP2848252A3 (de) 2007-03-23 2015-06-17 The Board of Regents of the University of Texas System Aldose-Reduktase-Inhibitoren zur Behandlung von Uveitis
US20090270490A1 (en) * 2008-04-24 2009-10-29 The Board Of Regents Of The University Of Texas System Methods involving aldose reductase inhibition
AU2011348074B2 (en) 2010-12-23 2016-04-28 The Board Of Regents Of The University Of Texas System Methods for treating COPD
WO2019165195A1 (en) 2018-02-22 2019-08-29 Srivastava Satish Combination therapy for the treatment of cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1173942A (en) * 1967-06-06 1969-12-10 Bellon Labor Sa Roger New 2,3-Dihydro-1,4-Benzoxazines
US3923709A (en) * 1974-08-30 1975-12-02 Monsanto Co 3,4-Dihydro-3-oxo-2H-1,4-benzothiazines and benzoxazines
IE58312B1 (en) * 1984-05-18 1993-09-08 Union Pharma Scient Appl Heterocyclic derivatives, processes for their preparation and drugs in which they are present, which are useful especially as aldose reductase inhibitors

Also Published As

Publication number Publication date
NO871526L (no) 1987-10-19
EP0243018B1 (de) 1990-10-24
IE60246B1 (en) 1994-06-15
PT84704B (pt) 1989-11-30
HUT45515A (en) 1988-07-28
AU602641B2 (en) 1990-10-18
ES2022889B3 (es) 1991-12-16
HU198699B (en) 1989-11-28
JPS63107970A (ja) 1988-05-12
KR870010024A (ko) 1987-11-30
NO871526D0 (no) 1987-04-10
CN1020098C (zh) 1993-03-17
EP0243018A1 (de) 1987-10-28
NO167916C (no) 1991-12-27
GR3001210T3 (en) 1992-07-30
FI89711B (fi) 1993-07-30
HK108293A (en) 1993-10-22
US4771050A (en) 1988-09-13
JPH034550B2 (de) 1991-01-23
CN87102891A (zh) 1987-11-04
FI871719A (fi) 1987-10-18
IE871012L (en) 1987-10-17
FI89711C (fi) 1993-11-10
DK184587D0 (da) 1987-04-10
NO167916B (no) 1991-09-16
DK184587A (da) 1987-10-18
FI871719A0 (fi) 1987-04-16
CA1287629C (en) 1991-08-13
AR244674A1 (es) 1993-11-30
SU1538895A3 (ru) 1990-01-23
AU7073087A (en) 1987-10-22
PT84704A (en) 1987-05-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee