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DE3683001D1 - Verwendung von benzylsulfinylbenzimidazolen als zytoprotektive arzneimittel fuer den magendarmkanal. - Google Patents

Verwendung von benzylsulfinylbenzimidazolen als zytoprotektive arzneimittel fuer den magendarmkanal.

Info

Publication number
DE3683001D1
DE3683001D1 DE8686306295T DE3683001T DE3683001D1 DE 3683001 D1 DE3683001 D1 DE 3683001D1 DE 8686306295 T DE8686306295 T DE 8686306295T DE 3683001 T DE3683001 T DE 3683001T DE 3683001 D1 DE3683001 D1 DE 3683001D1
Authority
DE
Germany
Prior art keywords
benzylsulfinylbenzimidazoles
gental
cytoprotective
canal
arm
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686306295T
Other languages
English (en)
Inventor
Shingoryouguchi-Cho Okabe
Masaru Satoh
Tomio Yamakawa
Yutaka Nomura
Masatoshi Hayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Chemiphar Co Ltd
Original Assignee
Nippon Chemiphar Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8226886A external-priority patent/JPH072636B2/ja
Application filed by Nippon Chemiphar Co Ltd filed Critical Nippon Chemiphar Co Ltd
Application granted granted Critical
Publication of DE3683001D1 publication Critical patent/DE3683001D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8686306295T 1985-08-14 1986-08-14 Verwendung von benzylsulfinylbenzimidazolen als zytoprotektive arzneimittel fuer den magendarmkanal. Expired - Fee Related DE3683001D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17895185 1985-08-14
JP8226886A JPH072636B2 (ja) 1985-08-14 1986-04-11 胃腸の細胞保護剤

Publications (1)

Publication Number Publication Date
DE3683001D1 true DE3683001D1 (de) 1992-01-30

Family

ID=26423292

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686306295T Expired - Fee Related DE3683001D1 (de) 1985-08-14 1986-08-14 Verwendung von benzylsulfinylbenzimidazolen als zytoprotektive arzneimittel fuer den magendarmkanal.

Country Status (4)

Country Link
US (1) US4824856A (de)
EP (1) EP0218336B1 (de)
AU (1) AU594074B2 (de)
DE (1) DE3683001D1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5433959A (en) * 1986-02-13 1995-07-18 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
CA1327010C (en) * 1986-02-13 1994-02-15 Tadashi Makino Stabilized solid pharmaceutical composition containing antiulcer benzimidazole compound and its production
US6749864B2 (en) 1986-02-13 2004-06-15 Takeda Chemical Industries, Ltd. Stabilized pharmaceutical composition
AU619444B2 (en) * 1986-06-02 1992-01-30 Nippon Chemiphar Co. Ltd. 2-(2-aminobenzylsulfinyl)- benzimidazole derivatives
EP0251536A1 (de) * 1986-06-24 1988-01-07 FISONS plc Benzimidazole, ihre Herstellung, Formulierung und Verwendung als Magensäuresekretionshemmer
EP0434999B1 (de) * 1989-11-29 1994-08-17 Toa Eiyo Ltd. Cycloheptenopyridinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Antiulkusmitteln
JP2002510293A (ja) * 1997-05-30 2002-04-02 ドクター・レディーズ・リサーチ・ファウンデーション 抗潰瘍剤として新規なベンゾイミダゾール誘導体、それらの製造方法、及びそれらを含有する薬学的組成物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
AU4640985A (en) * 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
EP0204215B1 (de) * 1985-05-24 1993-08-11 G.D. Searle & Co. 2-[(1H-Benzimidazol-2-ylsulfonyl)methyl]-benzenamine
WO1987000114A1 (en) * 1985-06-26 1987-01-15 Collin Stuart Camp Machine tool
EP0232399A1 (de) * 1985-08-21 1987-08-19 Byk Gulden Lomberg Chemische Fabrik GmbH Neue amine, verfahren zu ihrer herstellung, ihre anwendung und sie enthaltende arzneimittel
US4851419A (en) * 1985-10-16 1989-07-25 Fisons Plc Certain 2-pyridinyl-phenylsulfinyl-benzoxazoles, the corresponding benzothiazoles or benzimidazoles having anti-inflammatory or gastric acid secretion inhibition activity

Also Published As

Publication number Publication date
EP0218336B1 (de) 1991-12-18
US4824856A (en) 1989-04-25
AU6115686A (en) 1987-02-19
EP0218336A3 (en) 1989-11-02
EP0218336A2 (de) 1987-04-15
AU594074B2 (en) 1990-03-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee