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DE3678805D1 - Indolderivate. - Google Patents

Indolderivate.

Info

Publication number
DE3678805D1
DE3678805D1 DE8686308712T DE3678805T DE3678805D1 DE 3678805 D1 DE3678805 D1 DE 3678805D1 DE 8686308712 T DE8686308712 T DE 8686308712T DE 3678805 T DE3678805 T DE 3678805T DE 3678805 D1 DE3678805 D1 DE 3678805D1
Authority
DE
Germany
Prior art keywords
indolder derivatives
indolder
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686308712T
Other languages
English (en)
Inventor
Michael Dennis Dowle
Brian Evans
Peter Clark
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858527620A external-priority patent/GB8527620D0/en
Priority claimed from GB858527619A external-priority patent/GB8527619D0/en
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE3678805D1 publication Critical patent/DE3678805D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16Tryptamines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE8686308712T 1985-11-08 1986-11-07 Indolderivate. Expired - Fee Related DE3678805D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858527620A GB8527620D0 (en) 1985-11-08 1985-11-08 Chemical compounds
GB858527619A GB8527619D0 (en) 1985-11-08 1985-11-08 Chemical compounds

Publications (1)

Publication Number Publication Date
DE3678805D1 true DE3678805D1 (de) 1991-05-23

Family

ID=26289987

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686308712T Expired - Fee Related DE3678805D1 (de) 1985-11-08 1986-11-07 Indolderivate.

Country Status (3)

Country Link
US (1) US4833153A (de)
EP (1) EP0225726B1 (de)
DE (1) DE3678805D1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
GB8724912D0 (en) 1987-10-23 1987-11-25 Wellcome Found Indole derivatives
IL96891A0 (en) * 1990-01-17 1992-03-29 Merck Sharp & Dohme Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
CA2042295A1 (fr) * 1990-05-15 1991-11-16 Jacques Chauveau Derives de mediateurs endogenes, leurs sels, procede de preparation, applications, et compositions les renfermant
AU646871B2 (en) * 1990-06-07 1994-03-10 Astrazeneca Uk Limited Therapeutic heterocyclic compounds
SK278998B6 (sk) * 1991-02-01 1998-05-06 Merck Sharp & Dohme Limited Deriváty imidazolu, triazolu a tetrazolu, spôsob i
TW263508B (de) * 1991-02-12 1995-11-21 Pfizer
US5639752A (en) * 1991-11-25 1997-06-17 Pfizer Inc Indole derivatives
US5409941A (en) * 1992-02-03 1995-04-25 Pfizer Inc. 5-heteroyl indole derivatives
GB9207396D0 (en) * 1992-04-03 1992-05-13 Merck Sharp & Dohme Therapeutic agents
GB9208463D0 (en) * 1992-04-16 1992-06-03 Merck Sharp & Dohme Therapeutic agents
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
GB9226537D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
ES2208955T3 (es) * 1996-11-26 2004-06-16 Nps Allelix Corp. Compuestos 5-ciclo-indolicos como ligandos del receptor 5-ht1d.
US5998438A (en) * 1996-11-26 1999-12-07 Allelix Biopharmaceuticals, Inc. 5-cyclo indole compounds
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
ATE360015T1 (de) 2002-07-31 2007-05-15 Critical Outcome Technologies Protein tyrosin kinase inhibitoren
DE60318089T2 (de) 2002-10-09 2008-12-04 Critical Outcome Technologies, Inc. Protein-tyrosine-kinase-inhibitoren
WO2008083491A1 (en) 2007-01-11 2008-07-17 Critical Outcome Technologies Inc. Compounds and method for treatment of cancer
CA2710039C (en) 2007-12-26 2018-07-03 Critical Outcome Technologies, Inc. Semicarbazones, thiosemicarbazones and related compounds and methods for treatment of cancer
EP3023426A1 (de) 2008-07-17 2016-05-25 Critical Outcome Technologies, Inc. Thiosemicarbazonhemmerverbindungen und krebsbehandlungsverfahren
EP3235818A3 (de) 2010-04-01 2018-03-14 Critical Outcome Technologies, Inc. Verbindungen zur behandlung von hiv

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472872A (en) * 1964-02-19 1969-10-14 Sterling Drug Inc Indolyl-lower-alkyl-amidoximes
DE1670497C3 (de) * 1967-06-06 1973-12-20 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt, Budapest Isochinohnderivate und Verfahren zu deren Herstellung
IL30281A (en) * 1967-07-11 1971-12-29 Chinoin Gyogyszer Es Vegyeszet Amidine history and process for their preparation
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
BE889929A (fr) * 1980-08-12 1982-02-11 Glaxo Group Ltd Derives de l'indole, leur preparation et leurs utilisations therapeutiques
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
GB8332434D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Production of chemical compounds

Also Published As

Publication number Publication date
US4833153A (en) 1989-05-23
EP0225726A1 (de) 1987-06-16
EP0225726B1 (de) 1991-04-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee