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DE3578862D1 - Verfahren zur herstellung von 5,6,7,8-tetrahydrofolsaeure. - Google Patents

Verfahren zur herstellung von 5,6,7,8-tetrahydrofolsaeure.

Info

Publication number
DE3578862D1
DE3578862D1 DE8585307636T DE3578862T DE3578862D1 DE 3578862 D1 DE3578862 D1 DE 3578862D1 DE 8585307636 T DE8585307636 T DE 8585307636T DE 3578862 T DE3578862 T DE 3578862T DE 3578862 D1 DE3578862 D1 DE 3578862D1
Authority
DE
Germany
Prior art keywords
producing
tetrahydrofolic acid
tetrahydrofolic
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8585307636T
Other languages
English (en)
Inventor
Yutaka Hirai
Masaaki Torisu
Eri Nagayoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP59221189A external-priority patent/JPS61100583A/ja
Priority claimed from JP12513085A external-priority patent/JPH0631237B2/ja
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Application granted granted Critical
Publication of DE3578862D1 publication Critical patent/DE3578862D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8585307636T 1984-10-23 1985-10-23 Verfahren zur herstellung von 5,6,7,8-tetrahydrofolsaeure. Expired - Fee Related DE3578862D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59221189A JPS61100583A (ja) 1984-10-23 1984-10-23 ５，６，７，８−テトラヒドロ葉酸の製造方法
JP12513085A JPH0631237B2 (ja) 1985-06-11 1985-06-11 ５，６，７，８−テトラヒドロ葉酸及びその誘導体の保存安定化方法

Publications (1)

Publication Number Publication Date
DE3578862D1 true DE3578862D1 (de) 1990-08-30

Family

ID=26461650

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585307636T Expired - Fee Related DE3578862D1 (de) 1984-10-23 1985-10-23 Verfahren zur herstellung von 5,6,7,8-tetrahydrofolsaeure.

Country Status (8)

Country Link
US (1) US4665176A (de)
EP (1) EP0179654B1 (de)
KR (2) KR870001648B1 (de)
AU (1) AU556498B2 (de)
CA (1) CA1234570A (de)
DE (1) DE3578862D1 (de)
DK (1) DK162997C (de)
MX (1) MX166400B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8621268D0 (en) * 1986-09-03 1986-10-08 Univ Strathclyde Separation of substances
CH673459A5 (de) * 1987-05-15 1990-03-15 Eprova Ag
CH681303A5 (de) * 1991-01-16 1993-02-26 Eprova Ag
US6162914A (en) * 1998-04-24 2000-12-19 Cerbios-Pharma S.A. Process for the reduction of pterins
US6552198B1 (en) 1998-10-14 2003-04-22 Kyowa Hakko Kogyo Co., Ltd. Method of stabilizing aqueous pyrazoloacridone derivative solution
CN114181210B (zh) * 2021-12-01 2024-04-26 深圳奥萨制药有限公司 一种四氢叶酸的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2717250A (en) * 1950-04-29 1955-09-06 American Cyanamid Co Formylation of tetrahydro-10-formylpteroic acid and amino acid amides
US2790802A (en) * 1954-05-06 1957-04-30 American Cyanamid Co Substituted tetrahydropteridines and method of preparing the same
US3870719A (en) * 1972-06-16 1975-03-11 Us Health Synthesis of n-5-methyltetrahydrohomofolic acid and related reduced derivatives of homofolic acid
JPS5883691A (ja) * 1981-11-13 1983-05-19 Kanegafuchi Chem Ind Co Ltd １′，２′−ジアシル−（６ｒ，ｓ）−５，６，７，８−テトラヒドロ−ｌ−ビオプテリンおよびその製法
JPS60178887A (ja) * 1984-02-23 1985-09-12 Kanegafuchi Chem Ind Co Ltd ５，６，７，８−テトラヒドロ−ｌ−ビオプテリンの製造法

Also Published As

Publication number Publication date
EP0179654A3 (en) 1987-08-05
KR860003253A (ko) 1986-05-21
KR880000092B1 (ko) 1988-02-23
EP0179654B1 (de) 1990-07-25
DK162997B (da) 1992-01-06
CA1234570A (en) 1988-03-29
DK486985A (da) 1986-04-24
AU556498B2 (en) 1986-11-06
US4665176A (en) 1987-05-12
DK486985D0 (da) 1985-10-23
KR870001648B1 (ko) 1987-09-18
AU4854685A (en) 1986-05-01
MX166400B (es) 1993-01-07
EP0179654A2 (de) 1986-04-30
DK162997C (da) 1992-06-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee