DE3481304D1 - Triazole als antifungale wirkstoffe. - Google Patents
Triazole als antifungale wirkstoffe.Info
- Publication number
- DE3481304D1 DE3481304D1 DE8484305708T DE3481304T DE3481304D1 DE 3481304 D1 DE3481304 D1 DE 3481304D1 DE 8484305708 T DE8484305708 T DE 8484305708T DE 3481304 T DE3481304 T DE 3481304T DE 3481304 D1 DE3481304 D1 DE 3481304D1
- Authority
- DE
- Germany
- Prior art keywords
- triazole
- optionally substituted
- active substances
- antifungal active
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 229940121375 antifungal agent Drugs 0.000 title abstract 3
- 150000003852 triazoles Chemical class 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 title 1
- 230000000843 anti-fungal effect Effects 0.000 title 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 2
- 239000003429 antifungal agent Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005553 heteroaryloxy group Chemical group 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
- 125000004193 piperazinyl group Chemical group 0.000 abstract 1
- -1 piperidino, morpholino Chemical group 0.000 abstract 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB838322983A GB8322983D0 (en) | 1983-08-26 | 1983-08-26 | Triazole antifungal agents |
Publications (1)
Publication Number | Publication Date |
---|---|
DE3481304D1 true DE3481304D1 (de) | 1990-03-15 |
Family
ID=10547916
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8484305708T Expired - Lifetime DE3481304D1 (de) | 1983-08-26 | 1984-08-22 | Triazole als antifungale wirkstoffe. |
Country Status (9)
Country | Link |
---|---|
US (2) | US4638007A (de) |
EP (1) | EP0136063B1 (de) |
JP (1) | JPS6072869A (de) |
AT (1) | ATE50250T1 (de) |
DE (1) | DE3481304D1 (de) |
DK (1) | DK164362C (de) |
GB (1) | GB8322983D0 (de) |
GR (1) | GR80203B (de) |
IE (1) | IE57755B1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1198240B (it) * | 1986-12-23 | 1988-12-21 | Agrimont Spa | Azolilderivati fungicidi |
JP3471831B2 (ja) * | 1991-12-09 | 2003-12-02 | 富山化学工業株式会社 | 新規なトリアゾール誘導体およびその塩 |
US6391903B1 (en) * | 1999-09-09 | 2002-05-21 | Sankyo Company, Limited | Triazole derivatives having antifungal activity |
US7039397B2 (en) * | 2003-07-30 | 2006-05-02 | Lear Corporation | User-assisted programmable appliance control |
CN112574038A (zh) * | 2021-01-07 | 2021-03-30 | 北京微量化学研究所 | 一种柠檬酸单酯的选择性合成方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2635663A1 (de) * | 1976-08-07 | 1978-02-09 | Bayer Ag | Azolyl-carbonsaeure-derivate, verfahren zu ihrer herstellung und ihre verwendung als fungizide |
US4235892A (en) * | 1979-02-05 | 1980-11-25 | Schering Corporation, Patent Dept. | 1-Aryl-2-acylamido-3-fluoro-1-propanols, methods for their use as antibacterial agents and compositions useful therefor |
ES8104203A1 (es) * | 1979-02-05 | 1981-04-16 | Schering Corp | Un procedimiento para la preparacion de un compuesto d-(treo-1-aril-2-acilamido-3-fluor-1-propanol |
DE2908378A1 (de) * | 1979-03-03 | 1980-09-11 | Hoechst Ag | Derivate des 1,2,4-triazols |
US4361557A (en) * | 1980-01-28 | 1982-11-30 | Schering Corporation | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor |
DE3018865A1 (de) * | 1980-05-16 | 1981-11-26 | Bayer Ag, 5090 Leverkusen | Antimikrobielle mittel |
JPS5758671A (en) * | 1980-09-25 | 1982-04-08 | Ishihara Sangyo Kaisha Ltd | Phenoxyalkylazole type compound and agricultural and gardening fungicide comprising it |
EP0061835B1 (de) * | 1981-03-18 | 1989-02-01 | Imperial Chemical Industries Plc | Triazolverbindungen, Verfahren zu deren Herstellung, deren Anwendung als Pflanzenfungizide und deren fungizide Zusammensetzungen |
DE3111238A1 (de) * | 1981-03-21 | 1982-10-07 | Bayer Ag, 5090 Leverkusen | Substituierte triazolylmethyl-oxirane, verfahren zu ihrer herstellung sowie ihre verwendung als zwischenprodukte |
GR78218B (de) * | 1981-07-02 | 1984-09-26 | Ciba Geigy Ag | |
DE3202602A1 (de) * | 1982-01-27 | 1983-08-04 | Bayer Ag, 5090 Leverkusen | Antimykotisches mittel |
DE3202604A1 (de) * | 1982-01-27 | 1983-08-04 | Bayer Ag, 5090 Leverkusen | Ether-derivate von substituierten 1-hydroxyalkyl-azolen, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide und pflanzenwachstumsregulatoren |
DE3202601A1 (de) * | 1982-01-27 | 1983-08-04 | Bayer Ag, 5090 Leverkusen | Substituierte 1 -hydroxyalkyl-azolyl-derivate, verfahren zu ihrer herstellung sowie ihrer verwendung als fungizide und pflanzenwachstumsregulatoren |
DE3202613A1 (de) * | 1982-01-27 | 1983-08-04 | Bayer Ag, 5090 Leverkusen | Antimykotische mittel |
DK161382C (da) * | 1982-04-01 | 1991-12-09 | Pfizer | Fremgangsmaade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf |
DK157135C (da) * | 1982-04-07 | 1990-04-02 | Pfizer | Analogifremgangsmaade til fremstilling af 1,2,4-triazol-forbindelser eller farmaceutisk acceptable syreadditionssalte deraf |
US4616027A (en) * | 1982-08-14 | 1986-10-07 | Pfizer Inc. | Antifungal 1-aryl-1-fluoroalkyl-2-(1H-1,2,4-triazol-1-yl)ethanols |
GB8312624D0 (en) * | 1983-05-07 | 1983-06-08 | Pfizer Ltd | Triazole antifungal agents |
DE3378764D1 (en) * | 1982-09-30 | 1989-02-02 | Pfizer Ltd | Triazole anti-fungal agents |
EP0113644A3 (de) * | 1983-01-06 | 1984-09-26 | Ciba-Geigy Ag | Halogenazolyl-propan-Derivate als mikrobizide und wuchsregulierende Mittel |
US4518604A (en) * | 1983-07-25 | 1985-05-21 | Pfizer Inc. | Antifungal 1-aryl-2-(1H-1,2,4-triazol-1yl)-1-perfluoroalkylethyl halides |
-
1983
- 1983-08-26 GB GB838322983A patent/GB8322983D0/en active Pending
-
1984
- 1984-08-20 US US06/642,301 patent/US4638007A/en not_active Expired - Lifetime
- 1984-08-22 DE DE8484305708T patent/DE3481304D1/de not_active Expired - Lifetime
- 1984-08-22 EP EP84305708A patent/EP0136063B1/de not_active Expired - Lifetime
- 1984-08-22 AT AT84305708T patent/ATE50250T1/de not_active IP Right Cessation
- 1984-08-24 DK DK404584A patent/DK164362C/da not_active IP Right Cessation
- 1984-08-24 IE IE2176/84A patent/IE57755B1/en not_active IP Right Cessation
- 1984-08-24 GR GR80203A patent/GR80203B/el unknown
- 1984-08-27 JP JP59178194A patent/JPS6072869A/ja active Granted
-
1986
- 1986-09-05 US US06/904,079 patent/US4727159A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DK164362B (da) | 1992-06-15 |
DK404584A (da) | 1985-02-27 |
JPH0425953B2 (de) | 1992-05-06 |
GR80203B (en) | 1985-01-02 |
IE57755B1 (en) | 1993-03-24 |
EP0136063A3 (en) | 1985-12-18 |
ATE50250T1 (de) | 1990-02-15 |
US4727159A (en) | 1988-02-23 |
EP0136063B1 (de) | 1990-02-07 |
DK404584D0 (da) | 1984-08-24 |
US4638007A (en) | 1987-01-20 |
DK164362C (da) | 1992-11-02 |
EP0136063A2 (de) | 1985-04-03 |
JPS6072869A (ja) | 1985-04-24 |
GB8322983D0 (en) | 1983-09-28 |
IE842176L (en) | 1985-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |