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DE2634238A1 - Dialysis liquor substitution in blood dialysis - uses cells with flexible membranes to allow balanced replacement - Google Patents

Dialysis liquor substitution in blood dialysis - uses cells with flexible membranes to allow balanced replacement

Info

Publication number
DE2634238A1
DE2634238A1 DE19762634238 DE2634238A DE2634238A1 DE 2634238 A1 DE2634238 A1 DE 2634238A1 DE 19762634238 DE19762634238 DE 19762634238 DE 2634238 A DE2634238 A DE 2634238A DE 2634238 A1 DE2634238 A1 DE 2634238A1
Authority
DE
Germany
Prior art keywords
chamber
valves
fresh
dialysate
pump
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19762634238
Other languages
German (de)
Inventor
Erich Dr Med Streicher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BERGHOF FORSCHUNGSINST
Original Assignee
BERGHOF FORSCHUNGSINST
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by BERGHOF FORSCHUNGSINST filed Critical BERGHOF FORSCHUNGSINST
Priority to DE19762634238 priority Critical patent/DE2634238A1/en
Publication of DE2634238A1 publication Critical patent/DE2634238A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/342—Adding solutions to the blood, e.g. substitution solutions
    • A61M1/3441—Substitution rate control as a function of the ultrafiltration rate
    • A61M1/3444—Substitution rate control as a function of the ultrafiltration rate in which the collected ultra-filtrate expels an equal volume of substitution fluid from a reservoir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1635—Constructional aspects thereof with volume chamber balancing devices between used and fresh dialysis fluid
    • A61M1/1639—Constructional aspects thereof with volume chamber balancing devices between used and fresh dialysis fluid linked by membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/30—Accessories; Auxiliary operation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3413—Diafiltration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3331—Pressure; Flow

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Water Supply & Treatment (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • External Artificial Organs (AREA)

Abstract

Identical volumes of liquor are substituted during blood dialysis. One or two chambers are divided into two compartments by an elastic membrane. Liquid input and output to these is controlled by an 8 way valve. During the 1st. stage a pump removes spent dialysate into the first chamber, at which the flexible membrane pumps out an equal colume of fresh dialysate or fresh substitute soln. from the second compartment. A second pump feeds fresh dialysate into the second compartment of the second chamber. This causes the displacement of an equivalent amount spent liquor from the first compartment, due to the valve arrangement. When the first chamber is filled a pressure rise occurs switching off the second pump, allowing the cycle to continue by reversing the roles of the two chambers. Used in blood filtration and dialysis. The problem is that displaced liquid in the blood has to be deplaced and this is normally done by metering pumps. The system avoids this.

Description

Vorrichtung zur Substitution identischer Volumina bei DialyseDevice for the substitution of identical volumes in dialysis

und Blutdiafiltration Die Erfindung betrifft eine Vorrichtung zur volumenidentischen Substitution, insbesondere von DialysierflUssigkeit bzw. Infusionslösung, bei der Dialyse bzw. bei der Blutdiafiltration, Bei der Dialyse an hochpermeablen Membranen lässt sich bei Verwendung der Ublichen Dialysegeräte die Ultrafiltrationsrate im offenen Kreislauf nicht kontrollieren. Bei der Blutdiafiltration muß die anfallende Menge Plasmawasserfiltrat durch eine volumengleiche Menge isotoner Substitutionslösung ersetzt werden. In beiden Fällen ist demnach der volumenidentische Ersatz von gewissen flUssigkeitsmengen erforderlich.and blood diafiltration The invention relates to an apparatus for volume-identical substitution, especially of dialysis fluid or infusion solution, in dialysis or in blood diafiltration, in dialysis on highly permeable Membranes can be used to reduce the ultrafiltration rate using the usual dialysis machines do not control in open circuit. In the case of blood diafiltration, the accumulating Amount of plasma water filtrate through an equal volume of isotonic substitution solution be replaced. In both cases, therefore, the volume-identical replacement of certain amounts of liquid required.

Bei der Dialyse wurde dieses Problem durch Verwendung eines geschlossenen SpUlflUssigkeitsreservoirs gelöst.With dialysis, this problem was addressed by using a closed Flushing fluid reservoirs released.

(lit.: N.K. Man u.a "Proceedings of the European Dialysis and Traniplant issociation 10, 1973 236).(lit .: N.K. Man et al. "Proceedings of the European Dialysis and Traniplant issociation 10, 1973 236).

Bei der Blutdiafiltration wird eine Kolbenproportionierungspumpe verwendet0 (lit.: Trans. Am. Soc. Artif. Int. Organs. 16, 1/7, 1970).A piston proportioning pump is used in blood diafiltration0 (lit .: Trans. Am. Soc. Artif. Int. Organs. 16, 1/7, 1970).

Ausgehend von diesen Stand der Technik liegt der vorliegenden Erfindung die Aufgabe zugrunde, die aufwendige Konstruktion des geschlossenen Systems zu vereinfachen und die Möglichkeit zu schaffen, alle konventionellen Single-Pass-Dialysegeräte zur Dialyse an hochpermeablen Membranen zu adaptieren bzv. die kostspielige Kolbenproportionierungspumpe durch eine einfachere und genauer arbeitende Apparatur zu ersetzen.The present invention is based on this prior art the underlying task is to simplify the complex construction of the closed system and the ability to create all conventional single-pass dialysis machines to adapt to dialysis on highly permeable membranes or the expensive piston proportioning pump to be replaced by a simpler and more accurate apparatus.

Diese Aufgabe wird nach der Erfindung mittels einer Vorrichtung gelöst, die mit Hilfe einer elastischen Membran in einem Hohlkörper identische Flüssigkeitavolumina verschiebt0 Die Erfindung wird durch die folgende Beschreibung der Konstruktion und der Arbeitsweise der Vorrichtung an Hand von zwei schematischen Abbildungen 1 und 2 näher erläutert: Abb. 1 zeigt eine Vorrichtung zur kontinuierlichen Substitution identischer Volumina, bei der zwei durch Je eine elastische Membran M unterteilte Hohlkörper 1 und 2 parallel betrieben werden.This object is achieved according to the invention by means of a device, the identical liquid volumes in a hollow body with the help of an elastic membrane The invention is made clear by the following description of construction and the mode of operation of the device on the basis of two schematic illustrations 1 and 2 explained in more detail: Fig. 1 shows a device for continuous substitution identical volumes, with two subdivided by an elastic membrane M each Hollow bodies 1 and 2 are operated in parallel.

Während der eine Hohlkörper zur Volusensubstitution bereitsteht, wird der andere für diesen Arbeitsgang vorbereitet.While one of the hollow bodies is available for volume substitution, the other prepares for this operation.

Die Steuerung erfolgt Uber ein 8-Wegeventil. Im ersten Arbeitsgang pumpt die Pumpe 1 verbrauchtes Dialysat bzw. Diafiltrat in die Kammer Al des Hohlkörpers 1. Dabei verschiebt die elastische Membran M eine volumengleiche Menge frischen Dialysats bzw.It is controlled via an 8-way valve. In the first step the pump 1 pumps used dialysate or diafiltrate into the chamber A1 of the hollow body 1. The elastic membrane M moves an equal volume of fresh Dialysate or

frischer Substitutionslösung aus der Kammer B1 des Hohlkörpers 1 in den Dialysator bzw. die Diatiltrationseinheit, da die Ventile 1, 2 geöffnet, und die Ventile 5, 6 geschlossen sind.fresh substitution solution from the chamber B1 of the hollow body 1 in the dialyzer or the diatiltration unit, since the valves 1, 2 are open, and the valves 5, 6 are closed.

Gleichzeitig fordert die Pulpe 2 frisches Dialysat bzv. frische Snbstitutionslasung in die Keiner B2 des Hohlkörpers 2. Dabei verschiebt die elastische Membran eine volumengleiche Menge verbrauchten Dialysats bzw. Diafiltrats aus der Kammer A2 des Hohlkörpers 2 in den Abfluß, da die Ventile 3, 4 geschlossen und die Ventile 7, 8 geöffnet sind. Wenn der Hohlkörper B2 gefUllt ist, erfolgt ein Druckanstieg, der über den Druckmonitor P2 die Pumpe 2 abschaltet. Da die Pumpe 2 eine höhere Förderleistung hat, tritt dieser Schaltvorgang immer ein, bevor der Hohlkörper Al gefüllt ist, so daß frisches Dialysat bzw. frische Substitutionsiösung schon vor Beendigung des Arbeitsvorgangs zur Verfügung steht. Wenn auch die Kammer Al gefüllt ist, kommt es dort ebenfalls zu einem Druckanstieg, der über den Druckmonitor P1 die Pumpe 2 wieder einschaltet und gleichzeitig die Ventile 1 bis 8 umschaltet, so daß die Apparatur mit dem zweiten Arbeitsgang beginnen kann. Die Pumpe 1 fördert nun das verbrauchte Dialysat bzw. Diafiltrat in die Kammer A2 des Hohlkörpers 2, dessen Membran das frische Dialysat bzw. die frische Substitutionslösung aus der Kammer B2 in den Dialysator bzw. die Diafiltrationseinheit drUckt. Dabei sind die Ventile 3, 4 geöffnet und die Ventile 7, 8 geschlossen. Währenddessen fördert die Pumpe 2 frisches Dialysat bzw. frische Substitutionslösung in die Kammer B1 des Hohlkörpers 1, dessen Membran das verbrauchte Dialysat bzw.At the same time, the pulp 2 calls for fresh dialysate or. fresh substitution solution in the none B2 of the hollow body 2. Here shifts the elastic A volume of the same volume of used dialysate or diafiltrate from the membrane Chamber A2 of the hollow body 2 into the drain, since the valves 3, 4 are closed and the Valves 7, 8 are open. When the hollow body B2 is filled, there is an increase in pressure, which switches off pump 2 via pressure monitor P2. Since the pump 2 has a higher Has delivery capacity, this switching process always occurs before the hollow body Al is filled, so that fresh dialysate or fresh substitution solution is already available Completion of the work process is available. Even if the chamber Al is filled is, there is also a pressure increase there, which is monitored via the pressure monitor P1 the pump 2 switches on again and at the same time switches over valves 1 to 8, so that the apparatus can begin the second operation. Pump 1 delivers now the used dialysate or diafiltrate into the chamber A2 of the hollow body 2, whose membrane is the fresh dialysate or the fresh substitution solution from the Press chamber B2 into the dialyzer or the diafiltration unit. There are those Valves 3, 4 open and valves 7, 8 closed. Meanwhile, the promotes Pump 2 fresh dialysate or fresh substitution solution into chamber B1 of the Hollow body 1, the membrane of which contains the used dialysate or

Diafiltrat aus der Kammer Al herausdrUckt. Dabei sind die Ventile 1, 2 geschlossen und 5, 6 geöffnet. Der folgende Druckanstieg in Kammer B1 schaltet die Ventile 1 bis 8 erneut um, so daß die Apparatur wieder mit dem ersten Arbeitsgang beginnen kann.Diafiltrate is pressed out of the chamber Al. There are the valves 1, 2 closed and 5, 6 open. The following increase in pressure in chamber B1 switches the valves 1 to 8 again so that the apparatus can start again with the first operation can begin.

Xit der erfindungsgemäßen Vorrichtung kann auch durch eine diskontinuierliche Substitution eine annähernd gleichmäßige Substitution erreicht werden wenn die ZufUhrung des frischen Dialysats bzw.Xit of the device according to the invention can also be carried out by a discontinuous Substitution an approximately uniform substitution can be achieved when the supply of the fresh dialysate or

der frischen Substitutionslösung sehr rasch im Vergleich zur Förderung des verbrauchten Dialysats bzw. der verbrauchten Substitutionslösung erfolgt. In diesem Fall genUgt ein Hohlkörper mit zwei durch eine Membran getrennten Kammern und ein 4-Wegeventil (Abb. 2).the fresh substitution solution very quickly compared to the promotion the used dialysate or the used substitution solution he follows. In this case, a hollow body with two chambers separated by a membrane is sufficient and a 4-way valve (Fig. 2).

Im ersten Arbeitsgang fördert die Pumpe 1 verbrauchtes Dialysat bzw. Diafiltrat in die Kwnier A des Hohlkörpers. Dabei verschiebt die elastische Membran M eine volumengleiche Menge frischen Dialygats bzw. frischer Substitutionslösung aus der Kammer B in den Dialysator bzw. die Diafiltrationseinheit, da die Ventile 1, 2 geöffnet und die Ventile 3, 4 geschlossen sind. Wenn die Kammer A gefüllt ist, kommt es zu einem Druckanstieg, der über den Druckmonitor P1 die Pumpe 1 abschaltet, die Ventile 1 bis 4 wrochaltet und die Pumpe 2 einschaltet. Die sehr schnell laufende Pumpe 2 fUllt nun im zweiten Arbeitsgang die Kammer B mit frischem Dialysat bzw.In the first step, pump 1 delivers used dialysate or Diafiltrate into the cavity A of the hollow body. The elastic membrane moves M an equal volume of fresh dialygate or fresh substitution solution from chamber B into the dialyzer or the diafiltration unit, as the valves 1, 2 are open and the valves 3, 4 are closed. When chamber A is full, there is a pressure increase, which switches off pump 1 via pressure monitor P1, valves 1 to 4 wroch and pump 2 switches on. The very fast running one In the second step, pump 2 now fills chamber B with fresh dialysate or

frischer Substitutionslösung und drückt über die elastische Membran das verbrauchte Dialysat bzw. Diafiltrat aus der Kammer A heraus in den Abfluß. Dabei sind die Ventile 1, 2 geschlossen und die Ventile 3, 4 geöffnet. Wenn die Kammer B gefUllt ist, kommt es zu einem Druckanstieg, der über den Druckmonitor P2 die Pumpe abschaltet, die Ventile 1 bis 4 umschaltet und die Pumpe 1 wieder einschaltet, so daß die Apparatur wieder mit dem ersten Arbeitsgang beginnen kann.fresh substitution solution and presses over the elastic membrane the used dialysate or diafiltrate from chamber A out into the drain. The valves 1, 2 are closed and the valves 3, 4 are open. If the Chamber B is filled, there is a pressure increase that is monitored by the pressure monitor P2 switches off the pump, switches over valves 1 to 4 and switches on pump 1 again, so that the apparatus can start again with the first operation.

LeerseiteBlank page

Claims (3)

Patentansprüche 1. Vorrichtung zur Substitution identischer Volumina bei Dialyse und Blutdiafiltration, gekennzeichnet durch die Kombination der folgenden Merkmale: a) Es sind bis zu zwei durch je eine elastische Membran (M1 und M2) in Kammern (AI/31) und (A2/B2) unterteilte Hohlkörper 1 und 2 angeordnet, wobei die Steuerung des Fldssigkeitszu- und -ablaufs zu diesen Hohikörpern durch ein 8-Wegeventil in der Weise erfolgt, daß im ersten Arbeitsgang eine Pumpe (1) verbrauchtes Dialysat bzw. Diafiltrat in die Kammer (A1) des Hohlkörpers (1) pumpt, wodurch die elastische Membran (M1) eine volumengleiche Menge frischen Dialysats bzv. frischer Substitutionslösung aus der Kammer (B1) des Hohlkörpers (1) in den Dialysator bzw. die Diafiltrationseinheit verschiebt, da die Ventile (1,2) geöffnet und die Ventile (5,6) geschlossen sind, b) eine Pumpe (2) fördert frisches Dialysat bzw. frische Substitutionalösung in die Kammer (B2) des Hohlkörpers (2), wobei die elastische Membran (M2) eine volumengleiche Menge verbrauchten Dialysats bzw. Diafiltrats aus der Kammer (A2) des Hohlkb.rpers (2) in den Abfluß verschiebt, da die Ventile (3,4) geschlossen und die Ventile (7,8) geöffnet sind, wodurch, wenn der Hohlkörper (B2) gefUllt ist, ein Druckanstieg erfolgt, der Ueber einen Druckmonitor (P2) eine Pumpe (2) abschaltet, so daß frisches Dialysat bzw. frische Substitutionalösung zur VerfUgung steht, wobei, wenn auch die Kammer (Al) gefüllt ist, es dort ebenfalls zu einem Druckanstieg kommt, der über den Druckmonitor (P1) die Pumpe (2) wieder einschaltet und gleichzeitig die Ventile (1 bis 8) umschaltet, so daß die Vorrichtung mit einem zweiten Arbeitsgang beginnen kann, c) eine Pumpe (1) fördert das verbrauchte Dialysat bzw. Diafiltrat in die Kammer (A2) des Hohlkörpers (2), dessen Membran (M2) das frische Dialysat bzv. die frische Substitutionslösung aus der Kammer (B2) in den Dialysator bzw. die Diafiltrationseinheit drückt, Dabei sind die Ventile (3,4) geöffnet und die Ventile (7,8) geschlossen, d) die Pumpe (2) fördert frisches Dialysat bzw. frische Substitutionslösung in die Kammer (B1) des Hohlkörpers (1), dessen Membran das verbrauchte Dialysat bzw. Diafiltrat aus der Kammer (Al) fierausdrückt, wobei die Ventile (1,2) geschlossen und die Ventile (5,6) geöffnet sind, und der darauf folgende Druckanstieg in Kammer (B1) die Ventile (1 bis 8) erneut umschaltet.Claims 1. Device for substituting identical volumes in dialysis and blood diafiltration, characterized by the combination of the following Features: a) There are up to two through an elastic membrane each (M1 and M2) in Chambers (AI / 31) and (A2 / B2) subdivided hollow bodies 1 and 2 are arranged, the Control of the liquid inflow and outflow to these hollow bodies by an 8-way valve takes place in such a way that a pump (1) used dialysate in the first step or diafiltrate is pumped into the chamber (A1) of the hollow body (1), whereby the elastic Membrane (M1) an equal volume of fresh dialysate or. fresh substitution solution from the chamber (B1) of the hollow body (1) into the dialyzer or the diafiltration unit moves because the valves (1,2) are open and the valves (5,6) are closed, b) a pump (2) conveys fresh dialysate or fresh substitution solution in the chamber (B2) of the hollow body (2), the elastic membrane (M2) having the same volume Amount of dialysate or diafiltrate used from the chamber (A2) of the hollow body (2) moves into the drain, because the valves (3, 4) are closed and the valves (7, 8) are open, whereby, when the hollow body (B2) is filled, there is an increase in pressure, which switches off a pump (2) via a pressure monitor (P2), so that fresh dialysate or fresh substitution solution is available, although the chamber (Al) is filled, there is also a pressure increase there comes, which switches the pump (2) on again via the pressure monitor (P1) and at the same time the valves (1 to 8) switches over, so that the device with a second operation can begin, c) a pump (1) conveys the used dialysate or diafiltrate into the chamber (A2) of the hollow body (2), the membrane (M2) of which contains the fresh dialysate bzv. the fresh substitution solution from the chamber (B2) into the dialyzer or the diafiltration unit presses, the valves (3, 4) are open and the Valves (7, 8) closed, d) the pump (2) conveys fresh dialysate or fresh Substitution solution in the chamber (B1) of the hollow body (1) whose membrane used the Dialysate or diafiltrate from the chamber (Al) fierexpresses, the valves (1,2) closed and the valves (5,6) are open, and the subsequent pressure increase in chamber (B1) switches the valves (1 to 8) again. 2. Vorrichtung nach Anspruch 1, dadurch gekennzeichnet, daß die Vorrichtung zur Substitution identischer Volumina bei Dialyse und Blutdiafiltration nur aus einem Hohlkörper mit zwei durch eine Membran (M) getrennten Kammern (Abb. 2, A und B) besteht.2. Apparatus according to claim 1, characterized in that the device for the substitution of identical volumes in dialysis and blood diafiltration only off a hollow body with two chambers separated by a membrane (M) (Fig. 2, A and B) exists. 3. Vorrichtung nach den Ansprüchen 1 und 2, dadurch gekennzeichnet, daß die Steuerung der Ventile und Pumpen durch Druckmonitoren erfolgt.3. Device according to claims 1 and 2, characterized in that that the valves and pumps are controlled by pressure monitors.
DE19762634238 1976-07-30 1976-07-30 Dialysis liquor substitution in blood dialysis - uses cells with flexible membranes to allow balanced replacement Pending DE2634238A1 (en)

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Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2838414A1 (en) * 1978-09-02 1980-03-06 Fresenius Chem Pharm Ind DEVICE FOR ULTRAFILTRATION CONTROL IN HAEMODIALYSIS
DE2944136A1 (en) * 1978-11-06 1980-05-22 Cordis Dow Corp METHOD AND DEVICE FOR AUTOMATICALLY CONTROLLING THE HEMODIALYSIS AT A PRE-SELECTED ULTRAFILTRATION SPEED
FR2457694A1 (en) * 1979-06-01 1980-12-26 Nice Cote Azur Assoc Rgle Aide Purificn. of blood by ultrafiltration - incorporating controlling of necessary loss of patient by volumetric measurement of liq. injected and liq. ultrafiltered
DE3006718A1 (en) * 1980-02-21 1981-09-03 Toray Industries, Inc., Tokyo METHOD FOR PREPARING A LIQUID FROM ACCURATELY DOSED INGREDIENTS AND DEVICE FOR IMPLEMENTING THE METHOD
EP0115835A1 (en) * 1983-01-28 1984-08-15 Fresenius AG Apparatus for removal of water from blood
DE2858204C2 (en) 1978-09-02 1984-10-25 Fresenius AG, 6380 Bad Homburg Device for hemodialysis and for withdrawing ultrafiltrate
DE3428828A1 (en) * 1984-08-04 1986-02-13 Karl-Theo 6652 Bexbach Braun DEVICE FOR CONVEYING MECHANICAL STRESS HIGH-SENSITIVE LIQUIDS
EP0234001A2 (en) * 1985-11-20 1987-09-02 CD Medical Inc. Extracorporeal fluid treatment method and system
US4857199A (en) * 1986-10-20 1989-08-15 Hospal Industrie Method and system for pumping two liquids in equal quantities in an artificial kidney
EP0373455A1 (en) * 1988-12-13 1990-06-20 B. Braun Melsungen AG Device for continuous hemofiltration and hemodiafiltration
DE4116178C1 (en) * 1991-05-17 1992-11-12 Fresenius Ag, 6380 Bad Homburg, De
DE19728800C1 (en) * 1997-07-05 1999-02-18 Fresenius Medical Care De Gmbh Arrangement for delivering liquid for medical treatment equipment
DE10239598B3 (en) * 2002-08-28 2004-05-06 Fresenius Medical Care Deutschland Gmbh Device for conveying liquids for a medical treatment device
DE102010023635A1 (en) 2010-06-14 2011-12-15 Fresenius Medical Care Deutschland Gmbh Device and method for conveying liquids into the treatment unit of a medical treatment device, in particular into the dialyzer of a dialysis machine
WO2012139764A1 (en) 2011-04-13 2012-10-18 Fresenius Medical Care Deutschland Gmbh Method and device for conveying a liquid to a filter unit of a medical treatment device
DE102011016870A1 (en) * 2011-04-13 2012-10-18 Fresenius Medical Care Deutschland Gmbh Device for conveying a fluid to a filter unit of a medical treatment device and method for measuring the pressure ...
DE102013019356A1 (en) 2013-11-19 2015-06-03 Fresenius Medical Care Deutschland Gmbh Apparatus and method for balancing fluids for an extracorporeal blood treatment device
WO2015135989A1 (en) 2014-03-13 2015-09-17 Fresenius Medical Care Deutschland Gmbh Device and method for balancing between an inflow into and an outflow from a medical treatment device
DE102014006821A1 (en) 2014-05-08 2015-11-12 Fresenius Medical Care Deutschland Gmbh Method for filling a container
CN109641095A (en) * 2016-08-20 2019-04-16 费森尤斯医疗护理德国有限责任公司 For providing the device and method and dialysis machine of dialysis liquid

Cited By (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2838414A1 (en) * 1978-09-02 1980-03-06 Fresenius Chem Pharm Ind DEVICE FOR ULTRAFILTRATION CONTROL IN HAEMODIALYSIS
DE2858204C2 (en) 1978-09-02 1984-10-25 Fresenius AG, 6380 Bad Homburg Device for hemodialysis and for withdrawing ultrafiltrate
DE2944136A1 (en) * 1978-11-06 1980-05-22 Cordis Dow Corp METHOD AND DEVICE FOR AUTOMATICALLY CONTROLLING THE HEMODIALYSIS AT A PRE-SELECTED ULTRAFILTRATION SPEED
FR2457694A1 (en) * 1979-06-01 1980-12-26 Nice Cote Azur Assoc Rgle Aide Purificn. of blood by ultrafiltration - incorporating controlling of necessary loss of patient by volumetric measurement of liq. injected and liq. ultrafiltered
DE3006718A1 (en) * 1980-02-21 1981-09-03 Toray Industries, Inc., Tokyo METHOD FOR PREPARING A LIQUID FROM ACCURATELY DOSED INGREDIENTS AND DEVICE FOR IMPLEMENTING THE METHOD
EP0115835A1 (en) * 1983-01-28 1984-08-15 Fresenius AG Apparatus for removal of water from blood
DE3428828A1 (en) * 1984-08-04 1986-02-13 Karl-Theo 6652 Bexbach Braun DEVICE FOR CONVEYING MECHANICAL STRESS HIGH-SENSITIVE LIQUIDS
WO1986001115A1 (en) * 1984-08-04 1986-02-27 Braun Karl Theo Device for pumping liquids which are highly sensitive to mechanical strains
EP0234001A2 (en) * 1985-11-20 1987-09-02 CD Medical Inc. Extracorporeal fluid treatment method and system
EP0234001A3 (en) * 1985-11-20 1989-05-03 CD Medical Inc. Extracorporeal fluid treatment method and system
US4857199A (en) * 1986-10-20 1989-08-15 Hospal Industrie Method and system for pumping two liquids in equal quantities in an artificial kidney
EP0373455A1 (en) * 1988-12-13 1990-06-20 B. Braun Melsungen AG Device for continuous hemofiltration and hemodiafiltration
DE4116178C1 (en) * 1991-05-17 1992-11-12 Fresenius Ag, 6380 Bad Homburg, De
EP0513672A1 (en) * 1991-05-17 1992-11-19 Fresenius AG Blood treatment device with volume balanced flow
DE19728800C1 (en) * 1997-07-05 1999-02-18 Fresenius Medical Care De Gmbh Arrangement for delivering liquid for medical treatment equipment
DE10239598B3 (en) * 2002-08-28 2004-05-06 Fresenius Medical Care Deutschland Gmbh Device for conveying liquids for a medical treatment device
US7125393B2 (en) 2002-08-28 2006-10-24 Fresenius Medical Care Deutschland Gmbh Device for carrying fluids for a medical treatment device
DE102010023635A1 (en) 2010-06-14 2011-12-15 Fresenius Medical Care Deutschland Gmbh Device and method for conveying liquids into the treatment unit of a medical treatment device, in particular into the dialyzer of a dialysis machine
WO2011157396A1 (en) 2010-06-14 2011-12-22 Fresenius Medical Care Deutschland Gmbh Method and device for delivering liquids into the treatment unit of a medical treatment device, in particular into the dialyser of a dialysis device
WO2012139764A1 (en) 2011-04-13 2012-10-18 Fresenius Medical Care Deutschland Gmbh Method and device for conveying a liquid to a filter unit of a medical treatment device
DE102011016870A1 (en) * 2011-04-13 2012-10-18 Fresenius Medical Care Deutschland Gmbh Device for conveying a fluid to a filter unit of a medical treatment device and method for measuring the pressure ...
DE102011016869A1 (en) 2011-04-13 2012-10-18 Fresenius Medical Care Deutschland Gmbh Apparatus and method for conveying a liquid to a filter unit of a medical treatment device
DE102011016870B4 (en) * 2011-04-13 2013-06-20 Fresenius Medical Care Deutschland Gmbh Device for conveying a fluid to a filter unit of a medical treatment device and method for measuring the pressure in the fluid flow system of such a device
DE102013019356A1 (en) 2013-11-19 2015-06-03 Fresenius Medical Care Deutschland Gmbh Apparatus and method for balancing fluids for an extracorporeal blood treatment device
WO2015135989A1 (en) 2014-03-13 2015-09-17 Fresenius Medical Care Deutschland Gmbh Device and method for balancing between an inflow into and an outflow from a medical treatment device
DE102014003619A1 (en) 2014-03-13 2015-09-17 Fresenius Medical Care Deutschland Gmbh Apparatus and method for balancing an inflow and outflow from a medical treatment device
US10220130B2 (en) 2014-03-13 2019-03-05 Fresenius Medical Care Deutschland Gmbh Device and method for balancing between an inflow into and an outflow out of a medical treatment device
DE102014006821A1 (en) 2014-05-08 2015-11-12 Fresenius Medical Care Deutschland Gmbh Method for filling a container
US10507273B2 (en) 2014-05-08 2019-12-17 Fresenius Medical Care Deutschland Gmbh Method of filling a container
DE102014006821B4 (en) 2014-05-08 2021-08-26 Fresenius Medical Care Deutschland Gmbh Method for filling a container in the dialysis machine
CN109641095A (en) * 2016-08-20 2019-04-16 费森尤斯医疗护理德国有限责任公司 For providing the device and method and dialysis machine of dialysis liquid

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