DE202023102783U1 - Composition of an antibacterial lotion with lemongrass oil enriched with bioactive substances - Google Patents
Composition of an antibacterial lotion with lemongrass oil enriched with bioactive substances Download PDFInfo
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- DE202023102783U1 DE202023102783U1 DE202023102783.0U DE202023102783U DE202023102783U1 DE 202023102783 U1 DE202023102783 U1 DE 202023102783U1 DE 202023102783 U DE202023102783 U DE 202023102783U DE 202023102783 U1 DE202023102783 U1 DE 202023102783U1
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- lotion
- antibacterial
- composition
- lemongrass oil
- oil
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- 239000006210 lotion Substances 0.000 title claims abstract description 64
- 230000000844 anti-bacterial effect Effects 0.000 title claims abstract description 52
- 239000001941 cymbopogon citratus dc and cymbopogon flexuosus oil Substances 0.000 title claims abstract description 41
- 230000000975 bioactive effect Effects 0.000 title claims abstract description 19
- 239000000203 mixture Substances 0.000 title claims abstract description 17
- 239000000126 substance Substances 0.000 title claims description 9
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims abstract description 18
- RGZSQWQPBWRIAQ-CABCVRRESA-N (-)-alpha-Bisabolol Chemical compound CC(C)=CCC[C@](C)(O)[C@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-CABCVRRESA-N 0.000 claims abstract description 9
- 239000001500 (2R)-6-methyl-2-[(1R)-4-methyl-1-cyclohex-3-enyl]hept-5-en-2-ol Substances 0.000 claims abstract description 9
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 claims abstract description 9
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 claims abstract description 9
- RGZSQWQPBWRIAQ-LSDHHAIUSA-N alpha-Bisabolol Natural products CC(C)=CCC[C@@](C)(O)[C@@H]1CCC(C)=CC1 RGZSQWQPBWRIAQ-LSDHHAIUSA-N 0.000 claims abstract description 9
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000005875 quercetin Nutrition 0.000 claims abstract description 9
- 229960001285 quercetin Drugs 0.000 claims abstract description 9
- 241000894006 Bacteria Species 0.000 claims abstract description 8
- 235000018936 Vitellaria paradoxa Nutrition 0.000 claims abstract description 8
- 241001135917 Vitellaria paradoxa Species 0.000 claims abstract description 8
- 229940057910 shea butter Drugs 0.000 claims abstract description 8
- 244000144927 Aloe barbadensis Species 0.000 claims abstract description 7
- 235000002961 Aloe barbadensis Nutrition 0.000 claims abstract description 7
- 235000011399 aloe vera Nutrition 0.000 claims abstract description 7
- 150000001765 catechin Chemical class 0.000 claims abstract description 7
- 235000005487 catechin Nutrition 0.000 claims abstract description 7
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 claims abstract description 7
- 235000019864 coconut oil Nutrition 0.000 claims abstract description 7
- 239000003240 coconut oil Substances 0.000 claims abstract description 7
- 230000005923 long-lasting effect Effects 0.000 claims abstract description 6
- 230000003078 antioxidant effect Effects 0.000 claims description 15
- 230000001093 anti-cancer Effects 0.000 claims description 11
- 239000003963 antioxidant agent Substances 0.000 claims description 11
- 235000006708 antioxidants Nutrition 0.000 claims description 11
- 230000000843 anti-fungal effect Effects 0.000 claims description 9
- 229940121375 antifungal agent Drugs 0.000 claims description 9
- 201000010099 disease Diseases 0.000 claims description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 5
- 208000035143 Bacterial infection Diseases 0.000 claims description 4
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 4
- 238000002560 therapeutic procedure Methods 0.000 claims description 4
- 241000228245 Aspergillus niger Species 0.000 claims description 3
- 244000063299 Bacillus subtilis Species 0.000 claims description 3
- 235000014469 Bacillus subtilis Nutrition 0.000 claims description 3
- 241000222122 Candida albicans Species 0.000 claims description 3
- 241000588724 Escherichia coli Species 0.000 claims description 3
- 241000589516 Pseudomonas Species 0.000 claims description 3
- 241000191967 Staphylococcus aureus Species 0.000 claims description 3
- 229940095731 candida albicans Drugs 0.000 claims description 3
- 238000002290 gas chromatography-mass spectrometry Methods 0.000 claims description 3
- 230000036555 skin type Effects 0.000 claims description 3
- 206010017533 Fungal infection Diseases 0.000 claims description 2
- 208000031888 Mycoses Diseases 0.000 claims description 2
- 230000001580 bacterial effect Effects 0.000 claims description 2
- MGJZITXUQXWAKY-UHFFFAOYSA-N diphenyl-(2,4,6-trinitrophenyl)iminoazanium Chemical compound [O-][N+](=O)C1=CC([N+](=O)[O-])=CC([N+]([O-])=O)=C1N=[N+](C=1C=CC=CC=1)C1=CC=CC=C1 MGJZITXUQXWAKY-UHFFFAOYSA-N 0.000 claims description 2
- 230000002538 fungal effect Effects 0.000 claims description 2
- 230000005764 inhibitory process Effects 0.000 claims description 2
- 235000017807 phytochemicals Nutrition 0.000 claims description 2
- 229930000223 plant secondary metabolite Natural products 0.000 claims description 2
- 239000002516 radical scavenger Substances 0.000 claims description 2
- 239000013065 commercial product Substances 0.000 claims 1
- 231100000338 sulforhodamine B assay Toxicity 0.000 claims 1
- 238000003210 sulforhodamine B staining Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 description 11
- 230000018109 developmental process Effects 0.000 description 5
- 230000003020 moisturizing effect Effects 0.000 description 4
- 230000000144 pharmacologic effect Effects 0.000 description 4
- 240000004784 Cymbopogon citratus Species 0.000 description 3
- 235000017897 Cymbopogon citratus Nutrition 0.000 description 3
- 230000003110 anti-inflammatory effect Effects 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 230000007794 irritation Effects 0.000 description 3
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 2
- IOOMXAQUNPWDLL-UHFFFAOYSA-N 2-[6-(diethylamino)-3-(diethyliminiumyl)-3h-xanthen-9-yl]-5-sulfobenzene-1-sulfonate Chemical compound C=12C=CC(=[N+](CC)CC)C=C2OC2=CC(N(CC)CC)=CC=C2C=1C1=CC=C(S(O)(=O)=O)C=C1S([O-])(=O)=O IOOMXAQUNPWDLL-UHFFFAOYSA-N 0.000 description 2
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 241000233866 Fungi Species 0.000 description 2
- 208000003351 Melanosis Diseases 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 230000003389 potentiating effect Effects 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 206010008570 Chloasma Diseases 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 206010014970 Ephelides Diseases 0.000 description 1
- 206010016936 Folliculitis Diseases 0.000 description 1
- VWYIWOYBERNXLX-KTKRTIGZSA-N Glycidyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OCC1CO1 VWYIWOYBERNXLX-KTKRTIGZSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 229930003427 Vitamin E Natural products 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000001028 anti-proliverative effect Effects 0.000 description 1
- 235000013871 bee wax Nutrition 0.000 description 1
- 239000012166 beeswax Substances 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000003124 biologic agent Substances 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000010495 camellia oil Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 1
- 235000019441 ethanol Nutrition 0.000 description 1
- 125000004494 ethyl ester group Chemical group 0.000 description 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
- 230000005802 health problem Effects 0.000 description 1
- 239000008240 homogeneous mixture Substances 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- QYDYPVFESGNLHU-KHPPLWFESA-N methyl oleate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC QYDYPVFESGNLHU-KHPPLWFESA-N 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- DUWWHGPELOTTOE-UHFFFAOYSA-N n-(5-chloro-2,4-dimethoxyphenyl)-3-oxobutanamide Chemical compound COC1=CC(OC)=C(NC(=O)CC(C)=O)C=C1Cl DUWWHGPELOTTOE-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 238000011275 oncology therapy Methods 0.000 description 1
- KYVUJPJYTYQNGJ-UHFFFAOYSA-N oxiran-2-ylmethyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC1CO1 KYVUJPJYTYQNGJ-UHFFFAOYSA-N 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 230000009759 skin aging Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000036620 skin dryness Effects 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- WHOYVNZMAORLBI-UHFFFAOYSA-N trans-p-Menth-2-ene-1,4-diol Chemical compound CC(C)C1(O)CCC(C)(O)C=C1 WHOYVNZMAORLBI-UHFFFAOYSA-N 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 235000019165 vitamin E Nutrition 0.000 description 1
- 229940046009 vitamin E Drugs 0.000 description 1
- 239000011709 vitamin E Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
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- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
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- Microbiology (AREA)
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- Birds (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
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- Oil, Petroleum & Natural Gas (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
Zusammensetzung einer antibakteriellen Lotion, die Zitronengrasöl enthält, das mit folgenden Bioaktivstoffen angereichert ist:
a. Zitronengrasöl: 10-20%;
b. Alpha-Bisabolol: 2-5%;
c. Catechine: 2-5%;
d. Quercetin: 1-3%;
e. Aloe-Vera-Gel: 10-20%;
f. Sheabutter: 10-20%; und
g. Kokosnussöl: 10-20%; wobei die Lotion Bakterien wirksam abtötet und eine lang anhaltende antibakterielle Wirkung aufweist.Composition of an antibacterial lotion containing lemongrass oil enriched with the following bioactives:
a. Lemongrass Oil: 10-20%;
b. Alpha-Bisabolol: 2-5%;
c. catechins: 2-5%;
i.e. Quercetin: 1-3%;
e. aloe vera gel: 10-20%;
f. Shea butter: 10-20%; and
G. coconut oil: 10-20%; the lotion effectively kills bacteria and has a long-lasting antibacterial effect.
Description
Die vorliegende Erfindung bezieht sich auf die Entwicklung einer antibakteriellen Lotion, die als Hauptbestandteil Zitronengrasöl enthält, das mit leistungsstarken Bioaktivstoffen angereichert ist, und die potenzielle Anwendungen in der Hautpflegeindustrie hat, insbesondere bei der Behandlung verschiedener Hautkrankheiten.The present invention relates to the development of an antibacterial lotion containing as its main ingredient lemongrass oil enriched with powerful bioactive ingredients, which has potential applications in the skin care industry, particularly in the treatment of various skin diseases.
Bakterielle Infektionen sind ein weit verbreitetes Problem, das Millionen von Menschen weltweit betrifft. Bakterien können eine Vielzahl von Hautinfektionen verursachen, darunter Akne, Follikulitis und Zellulitis. Diese Infektionen können schmerzhaft und unansehnlich sein, und wenn sie unbehandelt bleiben, können sie zu ernsteren Gesundheitsproblemen führen. Es besteht ein Bedarf an wirksamen und sicheren antibakteriellen Produkten, die helfen können, bakterielle Infektionen zu verhindern und zu behandeln.Bacterial infections are a common problem affecting millions of people worldwide. Bacteria can cause a variety of skin infections, including acne, folliculitis, and cellulitis. These infections can be painful and unsightly, and if left untreated, can lead to more serious health problems. There is a need for effective and safe antibacterial products that can help prevent and treat bacterial infections.
Antibakterielle Lotionen werden verwendet, um Bakterien auf der Haut abzutöten und die Ausbreitung von Infektionen zu verhindern. Die meisten antibakteriellen Lotionen enthalten jedoch scharfe Chemikalien, die zu Trockenheit und Reizungen der Haut führen können. Es ist bekannt, dass Zitronengrasöl antimikrobielle Eigenschaften besitzt, was es zu einem geeigneten natürlichen Inhaltsstoff für die Verwendung in antibakteriellen Lotionen macht. Darüber hinaus haben die bioaktiven Verbindungen im Zitronengrasöl Berichten zufolge antioxidative, entzündungshemmende und wundheilende Eigenschaften. Es wurde festgestellt, dass Zitronengrasöl starke pharmakologische Aktivitäten besitzt, einschließlich antibakterieller, antimykotischer, antioxidativer und krebshemmender Eigenschaften. Die Erfindung stellt eine Zusammensetzung bereit, die Zitronengrasöl-Extrakt enthält, sowie ein Verfahren zur Verwendung der Zusammensetzung für verschiedene therapeutische Anwendungen.Antibacterial lotions are used to kill bacteria on the skin and prevent the spread of infection. However, most antibacterial lotions contain harsh chemicals that can cause skin dryness and irritation. Lemongrass oil is known to possess antimicrobial properties, making it a suitable natural ingredient for use in antibacterial lotions. Additionally, the bioactive compounds in lemongrass oil have been reported to have antioxidant, anti-inflammatory, and wound-healing properties. Lemongrass oil has been found to possess potent pharmacological activities including antibacterial, antifungal, antioxidant and anticancer properties. The invention provides a composition containing lemongrass oil extract and a method of using the composition for various therapeutic applications.
Die Erfindung offenbart eine Lotion, die Zitronengras-Essenz als Rohmaterial verwendet und zum Bereich der Hautpflegeprodukte gehört. Die Lotion wird aus Rohstoffen in folgenden Gewichtsanteilen hergestellt: 12-18 Teile der Zitronengras-Essenz, 2-8 Teile Polyethylenglykol, 4-12 Teile Teeöl, 2-4 Teile Ethylalkohol, 8-12 Teile Bienenwachs, 1-2 Teile Vitamin A, 0,5-1 Teil Vitamin B2, 1-1,4 Teile Vitamin C und 0,8-1 Teil Vitamin E. Die Lotion wirkt bakterientötend, antibakteriell, reguliert die Ölsekretion, fördert die Blutzirkulation, hellt und strafft die Haut, peelt die Haut, behandelt Akne, beugt Chloasma und Sommersprossen vor und behandelt sie und beugt der Hautalterung vor. Die vorliegende Erfindung unterscheidet sich hiervon, da sie die Entwicklung einer antibakteriellen Lotion betrifft, die als Hauptbestandteil Zitronengrasöl enthält, das mit leistungsstarken Bioaktivstoffen angereichert ist.The invention discloses a lotion using essence of lemongrass as a raw material and belonging to the field of skin care products. The lotion is made from raw materials in the following proportions by weight: 12-18 parts of lemongrass essence, 2-8 parts of polyethylene glycol, 4-12 parts of tea oil, 2-4 parts of ethyl alcohol, 8-12 parts of beeswax, 1-2 parts of vitamin A, 0.5-1 part of vitamin B2, 1-1.4 parts of vitamin C and 0.8-1 part of vitamin E. The lotion has bactericidal, antibacterial, regulates the Oil secretion, promote blood circulation, whiten and tighten the skin, exfoliate the skin, treat acne, prevent and treat chloasma and freckles, and prevent skin aging. The present invention differs therefrom as it relates to the development of an antibacterial lotion containing as a key ingredient lemongrass oil enriched with powerful bioactives.
Der Hauptnachteil des oben genannten Standes der Technik ist, dass antibakterielle Lotionen scharfe Chemikalien enthalten, die Trockenheit und Reizungen auf der Haut verursachen können.The main disadvantage of the above prior art is that antibacterial lotions contain harsh chemicals that can cause dryness and irritation on the skin.
Die Vorteile der vorliegenden Erfindung waren:
- Natürliche Inhaltsstoffe: Die Lotion enthält natürliche Inhaltsstoffe wie Zitronengrasöl, Alpha-Bisabolol, Catechine und Quercetin, die weniger schädlich für die Haut sein können als herkömmliche antibakterielle Lotionen, die schädliche Chemikalien enthalten.
- Natural Ingredients: The lotion contains natural ingredients such as lemongrass oil, alpha-bisabolol, catechins and quercetin, which may be less harmful to the skin than traditional antibacterial lotions that contain harmful chemicals.
Breites Wirkungsspektrum: Es wurde festgestellt, dass die Lotion antibakterielle, antimykotische, antioxidative und krebshemmende Eigenschaften aufweist, was sie für die Behandlung einer Vielzahl von Hautkrankheiten nützlich machen könnte.Broad Spectrum of Action: The lotion has been found to have antibacterial, antifungal, antioxidant and anti-cancer properties, which could make it useful for treating a variety of skin conditions.
Potenziell wirksam: Die Lotion hat sich als wirksam gegen eine Reihe von Bakterien und Pilzen erwiesen, darunter Staphylococcus aureus, Bacillus subtilis, Pseudomonas aureginosa, Escherichia coli, Candida albicans und Aspergillusniger.Potentially Effective: The lotion has been shown to be effective against a range of bacteria and fungi including Staphylococcus aureus, Bacillus subtilis, Pseudomonas aureginosa, Escherichia coli, Candida albicans and Aspergillus niger.
Potenziell sicher: Die natürlichen Inhaltsstoffe in der Lotion machen sie möglicherweise sicher für die Anwendung auf der Haut, mit weniger Nebenwirkungen oder unerwünschten Reaktionen als herkömmliche antibakterielle Lotionen.Potentially Safe: The natural ingredients in the lotion make it potentially safe for use on the skin, with fewer side effects or adverse reactions than traditional antibacterial lotions.
Feuchtigkeitsspendend: Der Zusatz von Inhaltsstoffen wie Aloe-Vera-Gel, Sheabutter und Kokosnussöl kann dazu beitragen, die Haut mit Feuchtigkeit zu versorgen und zu nähren, wodurch Trockenheit und Reizungen verringert werden.Moisturizing: The addition of ingredients like aloe vera gel, shea butter, and coconut oil can help hydrate and nourish skin, reducing dryness and irritation.
Insgesamt bietet die Erfindung eine potenziell wirksame, natürliche und sichere Option für Personen, die nach einer antibakteriellen Lotion suchen, die eine Vielzahl von Hautzuständen behandeln kann, ohne Trockenheit oder Reizungen zu verursachen.Overall, the invention offers a potentially effective, natural, and safe option for individuals looking for an antibacterial lotion that can treat a variety of skin conditions without causing dryness or irritation.
Ein Ziel der vorliegenden Offenbarung ist es, eine Zusammensetzung einer antibakteriellen Lotion bereitzustellen, die Zitronengrasöl enthält, das mit starken bioaktiven Substanzen angereichert ist.An object of the present disclosure is to provide an antibacterial lotion composition containing lemongrass oil enriched with potent bioactive substances.
Ein weiteres Ziel der vorliegenden Offenbarung ist die Bereitstellung einer antibakteriellen Lotion, die Zitronengrasöl enthält, das mit leistungsstarken biologischen Wirkstoffen angereichert ist, die Bakterien und Pilze auf der Haut wirksam abtöten können, während sie gleichzeitig Nährstoffe und Feuchtigkeit spenden.Another object of the present disclosure is to provide an antibacterial lotion containing lemongrass oil enriched with powerful biological agents that can effectively kill bacteria and fungi on the skin while nourishing and moisturizing.
Ein weiteres Ziel der vorliegenden Offenbarung ist die Bereitstellung einer natürlichen Therapie, die bei verschiedenen Krankheiten, einschließlich bakterieller und Pilzinfektionen, eingesetzt werden kann, indem die antibakteriellen, pilzhemmenden, antioxidativen und krebshemmenden Eigenschaften des Zitronengrasöls und der Bioaktivstoffe in der Lotion genutzt werden.Another object of the present disclosure is to provide a natural therapy that can be used for various diseases, including bacterial and fungal infections, by utilizing the antibacterial, antifungal, antioxidant and anticancer properties of lemongrass oil and the bioactives in the lotion.
Ein weiterer Gegenstand der vorliegenden Offenbarung ist, dass die Erfindung darauf abzielt, eine sichere, wirksame und erschwingliche Alternative zu antibakteriellen Lotionen auf chemischer Basis zu schaffen, die negative Nebenwirkungen haben oder zur Entwicklung von antibiotikaresistenten Bakterien beitragen können.Another object of the present disclosure is that the invention aims to provide a safe, effective, and affordable alternative to chemical-based antibacterial lotions that may have negative side effects or contribute to the development of antibiotic-resistant bacteria.
Andere Objekte und Vorteile der vorliegenden Offenbarung werden aus der folgenden Beschreibung, die nicht beabsichtigt ist, den Umfang der vorliegenden Offenbarung zu begrenzen, deutlicher werden.Other objects and advantages of the present disclosure will become more apparent from the following description, which is not intended to limit the scope of the present disclosure.
Die vorliegende Erfindung ist allgemein auf die Bereitstellung einer Zusammensetzung von antibakteriellen Lotion, die Zitronengrasöl mit leistungsstarken bioaktiven Substanzen angereichert. Die Lotion ist so formuliert, dass sie eine lang anhaltende antibakterielle Wirkung hat und gleichzeitig die Haut mit Feuchtigkeit versorgt und pflegt. Zu den der Lotion zugesetzten Bioaktivstoffen gehören Alpha-Bisabolol, Catechine und Quercetin, die die antibakteriellen, entzündungshemmenden und antioxidativen Eigenschaften der Lotion verstärken.The present invention is generally directed to providing an antibacterial lotion composition containing lemongrass oil enriched with powerful bioactive substances. The lotion is formulated to have a long-lasting antibacterial effect while moisturizing and nourishing the skin. Bioactives added to the lotion include alpha-bisabolol, catechins, and quercetin, which enhance the lotion's antibacterial, anti-inflammatory, and antioxidant properties.
Die vorliegende Erfindung bezieht sich allgemein auf eine antibakterielle Lotion, die Zitronengrasöl (LGO) enthält, das mit leistungsstarken Bioaktivstoffen wie Alpha-Bisabolol, Catechinen und Quercetin angereichert ist. LGO besitzt ein breites Spektrum an pharmakologischen Aktivitäten, darunter antibakterielle, antimykotische, antioxidative und krebshemmende Eigenschaften, die durch die Bioaktivstoffe in der Lotion verstärkt werden. Die Lotion enthält außerdem Aloe-Vera-Gel, Sheabutter und Kokosnussöl, die der Haut Feuchtigkeit spenden und sie nähren. Die Lotion ist für alle Hauttypen geeignet und bietet eine lang anhaltende antibakterielle Wirkung. Diese Erfindung hat das Potenzial, zu einer natürlichen Therapie für verschiedene Krankheiten entwickelt zu werden.The present invention relates generally to an antibacterial lotion containing lemongrass oil (LGO) enriched with powerful bioactives such as alpha-bisabolol, catechins and quercetin. LGO possesses a broad spectrum of pharmacological activities, including antibacterial, antifungal, antioxidant and anticancer properties, which are enhanced by the bioactive ingredients in the lotion. The lotion also contains aloe vera gel, shea butter and coconut oil to moisturize and nourish the skin. The lotion is suitable for all skin types and offers a long-lasting antibacterial effect. This invention has the potential to be developed into a natural therapy for various diseases.
Die vorliegende Erfindung ist eine antibakterielle Lotion, die Zitronengrasöl (LGO) enthält, das mit leistungsstarken Bioaktivstoffen angereichert ist. LGO besitzt nachweislich ein breites Spektrum an pharmakologischen Aktivitäten, einschließlich antibakterieller, antimykotischer, antioxidativer und krebshemmender Eigenschaften. In dieser Studie wurde ätherisches Öl aus Zitronengras mit n-Hexan extrahiert, und die phytochemischen Bestandteile wurden mit Gaschromatographie-Massenspektrometrie (GC-MS) untersucht. Die antibakteriellen, antimykotischen, antioxidativen und krebshemmenden Aktivitäten von LGO wurden ebenfalls bewertet.The present invention is an antibacterial lotion containing Lemongrass Oil (LGO) enriched with powerful bioactives. LGO has been shown to possess a broad spectrum of pharmacological activities, including antibacterial, antifungal, antioxidant and anticancer properties. In this study, lemongrass essential oil was extracted with n-hexane and the phytochemical components were analyzed by gas chromatography-mass spectrometry (GC-MS). LGO's antibacterial, antifungal, antioxidant and anticancer activities were also evaluated.
Die GC-MS-Analyse des LGO-Extrakts ergab das Vorhandensein von sieben wichtigen bioaktiven Verbindungen, darunter n-Hexadecansäure, 1,4-Dihydroxy-p-menth-2-en, 9-Octadecensäure(Z)-,Methylester, 9-Octadecensäure(Z)-, Oxiranylmethylester, Glycidylpalmitat, Propansäure und 2-Methyl-,1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethylester. Diese Verbindungen tragen zu den antibakteriellen, antimykotischen, antioxidativen und krebshemmenden Eigenschaften von LGO bei.GC-MS analysis of the LGO extract revealed the presence of seven important bioactive compounds including n-hexadecanoic acid, 1,4-dihydroxy-p-menth-2-ene, 9-octadecenoic acid(Z)-, methyl ester, 9-octadecenoic acid(Z)-, oxiranyl methyl ester, glycidyl palmitate, propanoic acid and 2-methyl-,1-methyl-1-(4-methyl-3-cyclo hexen-1-yl)ethyl ester. These compounds contribute to LGO's antibacterial, antifungal, antioxidant, and anticancer properties.
Die antibakterielle Aktivität von LGO wurde anhand der Hemmhofmethode gegen die Bakterien Staphylococcus aureus, Bacillus subtilis, Pseudomonas aureginosa, Escherichia coli und die Pilzstämme Candida albicans und Aspergillusniger untersucht. Die Ergebnisse zeigten, dass LGO das Wachstum all dieser Mikroorganismen wirksam hemmt, was auf sein Potenzial als natürliches antibakterielles Mittel hinweist.The antibacterial activity of LGO was evaluated using the zone of inhibition method against the bacteria Staphylococcus aureus, Bacillus subtilis, Pseudomonas aureginosa, Escherichia coli and the fungal strains Candida albicans and Aspergillus niger. The results showed that LGO effectively inhibited the growth of all these microorganisms, indicating its potential as a natural antibacterial agent.
Die antioxidative Aktivität von LGO wurde mit Hilfe der DPPH-Radikalfängermethode untersucht. Die Ergebnisse zeigten, dass LGO eine hohe antioxidative Kapazität besitzt und freie Radikale, die bekanntermaßen zu Alterung und Krankheit beitragen, wirksam abfangen kann. The antioxidant activity of LGO was studied using the DPPH radical scavenger method. The results showed that LGO has high antioxidant capacity and can effectively scavenge free radicals, which are known to contribute to aging and disease.
Das Anti-Krebs-Potenzial von LGO wurde mit dem Sulforhodamin B (SRB)-Test bewertet. Die Ergebnisse zeigten, dass LGO proliferationshemmende Eigenschaften gegen Krebszellen hat, was es zu einem potenziellen Kandidaten für die Entwicklung neuer Krebstherapien macht.LGO's anti-cancer potential was assessed using the Sulforhodamine B (SRB) test. The results showed that LGO has anti-proliferative properties against cancer cells, making it a potential candidate for the development of new cancer therapies.
Die antibakterielle Lotion der vorliegenden Erfindung enthält Zitronengrasöl, das mit starken Bioaktivstoffen angereichert ist. Die Lotion wird durch Mischen von 10-20% Zitronengrasöl mit 2-5% Alpha-Bisabolol, 2-5% Catechinen und 1-3% Quercetin hergestellt. Zu den übrigen Bestandteilen gehören Aloe-Vera-Gel, Sheabutter und Kokosnussöl, die jeweils zu 10-20 Gewichtsprozent enthalten sind. Zur Herstellung der Lotion werden die Inhaltsstoffe in einem geeigneten Behälter vermischt und vermengt, bis eine homogene Mischung entsteht. Die Lotion wird dann in einem geeigneten Behälter für den Gebrauch verpackt.The antibacterial lotion of the present invention contains lemongrass oil enriched with powerful bioactives. The lotion is made by blending 10-20% lemongrass oil with 2-5% alpha-bisabolol, 2-5% catechins, and 1-3% quercetin. The remaining ingredients include aloe vera gel, shea butter and coconut oil, each at 10-20% by weight. To prepare the lotion, the ingredients are mixed in a suitable container and blended until a homogeneous mixture is obtained. The lotion is then packaged in a suitable container for use.
Die Lotion der vorliegenden Erfindung ist für alle Hauttypen geeignet, auch für empfindliche Haut. Die Lotion bietet eine lang anhaltende antibakterielle Wirkung, während sie gleichzeitig die Haut mit Feuchtigkeit versorgt und nährt. Die der Lotion zugesetzten Bioaktivstoffe verstärken die antibakteriellen, entzündungshemmenden und antioxidativen Eigenschaften der Lotion. Die Lotion lässt sich leicht auftragen, zieht schnell in die Haut ein und hinterlässt keine fettigen Rückstände.The lotion of the present invention is suitable for all skin types, including sensitive skin. The lotion provides a long-lasting antibacterial effect while moisturizing and nourishing the skin. The lotion supplied These bioactive ingredients enhance the lotion's antibacterial, anti-inflammatory and antioxidant properties. The lotion is easy to apply, absorbs quickly into the skin and leaves no greasy residue.
Zusammenfassend lässt sich sagen, dass die vorliegende Erfindung eine antibakterielle Lotion bereitstellt, die LGO enthält, angereichert mit leistungsstarken Bioaktivstoffen, die ein breites Spektrum an pharmakologischen Aktivitäten aufweisen. Die Lotion hat antibakterielle, antimykotische, antioxidative und krebshemmende Eigenschaften, was sie zu einem potenziellen Kandidaten für die Entwicklung neuer natürlicher Therapien für verschiedene Krankheiten macht.In summary, the present invention provides an antibacterial lotion containing LGO enriched with powerful bioactives that exhibit a broad spectrum of pharmacological activities. The lotion has antibacterial, antifungal, antioxidant, and anticancer properties, making it a potential candidate for the development of new natural therapies for various diseases.
Beispieleexamples
- 1. Zusammensetzung einer antibakteriellen Lotion, die Zitronengrasöl enthält, das mit folgenden Bioaktivstoffen angereichert ist:
- a) Zitronengrasöl: 10-20%;
- b) Alpha-Bisabolol: 2-5%;
- c) Catechine: 2-5%;
- d) Quercetin: 1-3%;
- e) Aloe-Vera-Gel: 10-20%;
- f) Sheabutter: 10-20%; und
- g) Kokosnussöl: 10-20%;
- 1. Composition of an antibacterial lotion containing lemongrass oil enriched with the following bioactive substances:
- a) lemongrass oil: 10-20%;
- b) alpha-bisabolol: 2-5%;
- c) catechins: 2-5%;
- d) quercetin: 1-3%;
- e) aloe vera gel: 10-20%;
- f) shea butter: 10-20%; and
- g) coconut oil: 10-20%;
Claims (10)
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